* co-first authors
# co-corresponding authors
2025
63. Distinct roles between eotaxin 1 and eotaxin 2 in asthmatic airways
Sim S, Yang EM, Shin YS, Kim SB, Choi Y#, Park HS#
Clin Transl Allergy, 15(7):e70077
62. Differential response of SNU-1826 colon cells on the autophagy, ER stress, and inflammation during the regulation of microplastic internalization
Seol A, Kim JE, Song HJ, Kim TR, Park ES, Park KH, Lim SJ, Wang SH, Park SC, Choi Y, Kim H, Seo S, Hwang DY
J Toxicol Sci, 50(7):361-378
61. Therapeutic potential of arginine-loaded red blood cell nanovesicles targeting obese asthma
Quoc QL*, Kim T*, Cao TBT, Choi I, Yang SY, An BS, Hwang DY, Choi Y#, Park HS#
Mediators Inflamm, 2025:8248722
60. Antioxidant and laxative effects of methanol extracts of green pine cones (Pinus densiflora) in SD rats with loperamide-induced constipation
Song HJ, Seol A, Park J, Kim JE, Kim TR, Park KH, Park ES, Lim SJ, Wang SH, Sung JE, Choi Y, Lee H, Hwang DY
Antioxidants, 14(1):37
2024
59. Ionic Character and Alkyl Chain Length of Surfactants Affect Titanium Dioxide Dispersion and Its UV-Blocking Efficacy
Mun J, Jeon Y, Jeong S, Lim JM, Kim Y, Myeong H, Han J, Choi Y, Jo SM, Yang SY, An BS , Hwang DY, Seo S
Appl Sci, 14(23):11035
58. Update on Inflammatory Biomarkers for Defining Asthma Phenotype
Sim S*, Choi Y*, Park HS
Allergy Asthma Immunol Res, 16(5):462-472
57. Novel therapeutic effects of Euphorbia heterophylla L. methanol extracts in blue light-induced macular degeneration in A2E-laden ARPE-19 cells and retina of BALB/c mice
Seol A, Kim JE, Jin YJ, Song HJ, Roh YJ, Kim TR, Park ES, Park KH, Park SH, Uddin S, Lee SW, Choi Y, Hwang DY
Pharmaceuticals, 17(9): 1193
56. Downregulation of otulin induces inflammasome activation in neutrophilic asthma
Quoc QL*, Kim Y*, Park G*, Cao TBT, Choi Y, Park YH#, Park HS#
J Allergy Clin Immunol, 154(3):557-570
55. Serum Galectin-10: A biomarker for persistent airflow limitation in adult asthmatics
Cao TBT*, Quoc LQ*, Jang JH, Yang EM, Ryu MS, Choi Y, Park HS
World Allergy Organ J, 17(9):100955
54. Association between cytokeratin 19-specific IgG and neutrophil activation in asthma
Quoc QL, Cao TBT, Seo S, An BS, Hwang DY, Choi Y#, Park HS#
Allergy Asthma Immunol Res, 16(4):353-371
53. Association between specific IgE to staphylococcal enterotoxin B and the eosinophilic phenotype of asthma
Sim S, Choi Y, Yang EM, Park HS
Korean J Intern Med, 39(4):659-667
52. Lactobacillus paracasei-derived extracellular vesicles alleviate neutrophilic asthma by inhibiting the JNK pathway in airway epithelium
Sim S, Park HJ, Kim YK, Choi Y#, Park HS#
Allergol Int, 73(2):302-312
51. Cannabinoid receptor 2 as a regulator of inflammation induced by oleoylethanolamide in eosinophilic asthma
Kwon EK*, Choi Y*, Sim S*, Ye YM, Shin YS, Park HS, Ban GY
J Allergy Clin Immunol, 153(4):998-1009
50. New targets for type 2-low asthma
Quoc QL*, Choi Y*, Hur GY, Park HS
Korean J Intern Med, 39(2):215-227
49. ST2-Mediated Neutrophilic Airway Inflammation: A Therapeutic Target for Patients With Uncontrolled Asthma
Quoc QL, Cao TBT, Jang JH, Shin YS, Choi Y#, Park HS#
Allergy Asthma Immunol Res, 16(1):22-41
48. Contribution of monocyte and macrophage extracellular traps to neutrophilic airway inflammation in severe asthma
Quoc QL, Cao TBT, Moon JY, Jang JH, Shin YS, Choi Y, Ryu MS, Park HS
Allergol Int, 73(1):81-93
2023
47. Calcium ionophore-activated platelets induce eosinophil extracellular trap formation
Sim MS, Kim HJ, Bae I, Kim C, Chang HS, Choi Y, Lee DH, Park HS, Chung IY
Allergol Int, 72(3):466-476
46. Tissue inhibitor of metalloproteinase-1 enhances eosinophilic airway inflammation in severe asthma
Cao TBT, Quoc QL, Yang EM, Moon JY, Shin YS, Ryu MS, Choi Y, Park HS
Allergy Asthma Immunol Res, 15(4):451-472
45. Bacterial Extracellular Vesicles: A Candidate Molecule for the Diagnosis and Treatment of Allergic Diseases
Choi Y, Park HS#, Kim YK#
Allergy Asthma Immunol Res, 15:279-89
44. Endocrine-disrupting chemical exposure augments neutrophilic inflammation in severe asthma through the autophagy pathway
Quoc QL, Cao TBT, Kim SH, Choi Y, Ryu MS, Choi Y, Park HS, Shin YS
Food Chem Toxicol, 175:113699
43. Micrococcus luteus-derived extracellular vesicles attenuate neutrophilic asthma by regulating miRNAs in airway epithelial cells
Sim S, Lee DH, Kim KS, Park HJ, Kim YK, Choi Y#, Park HS#
Exp Mol Med, 55(1):196–204
2022
42. Immunologic Basis of Type 2 Biologics for Severe Asthma
Sim S*, Choi Y*, Park HS
Immune Netw, 22(6):e45
41. Epithelial autoantigen-specific IgG antibody enhances eosinophil extracellular trap formation in severe asthma
Lee DH, Sim S, Jang, J, Choi Y#, Park HS#
Allergy Asthma Immunol Res, 14(5):479-493
40. Extracellular Traps: A Novel Therapeutic Target for Severe Asthma
Choi Y, Luu QQ, Park HS
J Asthma Allergy, 15:803-810
39. Immunoregulatory effects of Lactococcus lactis-derived extracellular vesicles in allergic asthma
Lee DH, Park HK, Lee HR, Sohn H, Sim S, Park HJ, Shin YS, Kim YK, Choi Y#, Park HS#
Clin Transl Allergy, 12(3):e12138
38. Serum Amyloid A1: A Biomarker for Neutrophilic Airway Inflammation in Adult Asthmatic Patients
Cao TBT, Quoc QL, Choi Y, Yang EM, Trinh HKT, Shin YS, Park HS
Allergy Asthma Immunol Res, 14(1):40-58
37. Contribution of dipeptidyl peptidase 10 to airway dysfunction in patients with NSAID-exacerbated respiratory disease
Sim S, Choi Y, Lee DH, Lee HR, Shin YS, Park HS
Clin Exp Allergy, 52(1):115-126
2021
36. Effect of TGF-β1 on eosinophils to induce cysteinyl leukotriene E4 production in aspirin-exacerbated respiratory disease
Choi Y, Sim S, Lee DH, Lee HR, Ban GY, Shin YS, Kim YK, Park HS
PLoS One, 16(8):e0256237
35. S100A9 in adult asthmatic patients: a biomarker for neutrophilic asthma
Quoc QL, Choi Y, Thi Bich TC, Yang EM, Shin YS, Park HS
Exp Mol Med, 53(7):1170-1179
34. Potential Metabolic Biomarkers in Adult Asthmatics
Sim S, Choi Y, Park HS
Metabolites, 11(7): 430
33. Oleoylethanolamide induces eosinophilic airway inflammation in bronchial asthma
Kwon EK, Choi Y, Yoon IH, Won HK, Sim S, Lee HR, Kim HS, Ye YM, Shin YS, Park HS, Ban GY
Exp Mol Med, 53(6):1036-1045
32. Engineering of humanized antibodies against human interleukin 5 receptor alpha subunit that cause potent antibody-dependent cell-mediated cytotoxicity
Kim JE, Lee DH, Jung K, Kim EJ, Choi Y, Park HS, Kim YS
Front Immunol, 11:593748
31. Urine Microbial Extracellular Vesicles Can Be Potential and Novel Biomarkers for Allergic Diseases
Choi Y, Park HS, Jee YK
Allergy Asthma Immunol Res, 13(1):5-7
2020
30. Lysophosphatidylserine induces eosinophil extracellular trap formation and degranulation: Implications in severe asthma
Kim HJ, Sim MS, Lee DH, Kim C, Choi Y, Park HS#, Chung IY#
Allergy, 75(12):3159-3170
29. Metabolic shift favoring C18:0 ceramide accumulation in obese asthma
Choi Y, Kim M, Kim SJ, Yoo HJ, Kim SH#, Park HS#
Allergy, 75(11):2858-2866
28. Pulmonary surfactants: A new therapeutic target in asthma
Choi Y, Jang J, Park HS
Curr Allergy Asthma Rep, 20(11):70
27. Diagnostic Models for Atopic Dermatitis Based on Serum Microbial Extracellular Vesicle Metagenomic Analysis: A Pilot Study
Yang J, McDowell A, Seo H, Kim S, Min TK, Jee YK, Choi Y, Park HS, Pyun BY#, Kim YK#
Allergy Asthma Immunol Res, 12(5):792-805
26. Distinct functions of eosinophils in severe asthma with type 2 phenotype: Clinical implications
Choi Y, Sim S, Park HS
Korean J Intern Med, 35(4):823-833
25. Is TLR4 Critical for Neutrophil Apoptosis in Occupational Asthma?
Choi Y, Sim S, Park HS
Allergy Asthma Immunol Res, 12(4):560-562
24. Lung Disease Diagnostic Model Through IgG Sensitization to Microbial Extracellular Vesicles
Yang J, Hong G, Kim YS, Seo H, Kim S, McDowell A, Lee WH, Kim YS, Oh YM, Cho YS, Choi Y, Kim YY, Jee YK#, Kim YK#
Allergy Asthma Immunol Res, 12(4):669-683
23. Altered gut microbiota by azithromycin attenuates airway inflammation in allergic asthma
Park HK*, Choi Y*, Lee DH, Kim S, Lee JM, Choi SW, Lee HR, Rho M, Park HS
J Allergy Clin Immunol, 145(5):1466-1469 e1468
22. Airway G-CSF identifies neutrophilic inflammation and contributes to asthma progression
Kim YM, Kim H, Lee S, Kim S, Lee JU, Choi Y, Park HW, You G, Kang H, Lee S, Park JS, Park Y, Park HS, Park CS, Lee SW
Eur Respir J, 55(2):1900827
21. Eosinophil extracellular traps activate type 2 innate lymphoid cells through stimulating airway epithelium in severe asthma
Choi Y, Kim YM, Lee HR, Mun J, Sim S, Lee DH, Duy PL, Kim SH, Shin YS, Lee SW, Park HS
Allergy, 75(1):95-103
2019
20. Serum Levels of Eosinophil-Derived Neurotoxin: A Biomarker for Asthma Severity in Adult Asthmatics
Lee Y, Lee JH, Yang EM, Kwon E, Jung CG, Kim SC, Choi Y, Cho YS, Kim CK, Park HS
Allergy Asthma Immunol Res, 11(3):394-405
19. Which Factors Associated with Activated Eosinophils Contribute to the Pathogenesis of Aspirin-exacerbated Respiratory Disease?
Choi Y, Lee Y, Park HS
Allergy Asthma Immunol Res, 11(3):320-329
18. The Synergistic Effects of Clopidogrel with Montelukast may be Beneficial for Asthma Treatment
Trinh HKT, Nguyen TVT, Choi Y, Park HS, Shin YS
J Cell Mol Med, 23(5):3441-3450
17. Neutrophil activation in occupational asthma
Choi Y, Lee Y, Park HS
Curr Opin Allergy Clin Immunol, 19(2):81-85
16. Characterization of cysteinyl leukotriene-related receptors and their interactions in a mouse model of asthma
Trinh HKT, Suh DH, Nguyen TVT, Choi Y, Park HS, Shin YS
Prostaglandins Leukot Essent Fatty Acids, 141:17-23
15. Immunomodulatory function of surfactant protein D in eosinophilic asthma
Choi Y, Lee DH, Lee JH, Shin YS, Kim SH, Park HS
Allergy, 74(1):192-195
14. Surfactant protein D alleviates eosinophil-mediated airway inflammation and remodeling in patients with aspirin-exacerbated respiratory disease
Choi Y, Lee DH, Trinh HKT, Ban GY, Park HK, Shin YS, Kim SH, Park HS
Allergy, 74(1):78-88
2018
13. Serum Periostin Levels: A Potential Serologic Marker for Toluene Diisocyanate-Induced Occupational Asthma
Lee JH, Kim SH, Choi Y, Trinh HKT, Yang EM, Ban GY, Shin YS, Ye YM, Izuhara K, Park HS
Yonsei Med J, 59(10):1214-1221
12. Epithelial folliculin enhances airway inflammation in aspirin-exacerbated respiratory disease
Trinh HKT, Pham DL, Choi Y, Kim HM, Kim SH, Park HS
Clin Exp Allergy, 48(11):1464-1473
11. Biological function of eosinophil extracellular traps in patients with severe eosinophilic asthma
Choi Y*, Pham LD*, Lee DH, Lee SH, Kim SH, Park HS
Exp Mol Med, 50(8):104
10. DW2008S and its major constituents from Justicia procumbens exert anti-asthmatic effect via multitargeting activity
Youm J, Lee H, Choi Y, Yoon J
J Cell Mol Med, 22(5):2680-2691
9. Akkermansia muciniphila-derived extracellular vesicles influence gut permeability through the regulation of tight junctions
Chelakkot C*, Choi Y*, Kim DK, Park HT, Ghim J, Kwon Y, Jeon J, Kim MS, Jee YK, Gho YS, Park HS, Kim YK#, Ryu SH#
Exp Mol Med, 50(2):e450
2017
8. Potential Biomarkers for NSAID-Exacerbated Respiratory Disease
Park H, Choi Y, Jung CG, Park HS
Mediators Inflamm, 2017:8160148
7. Neutrophil Extracellular DNA Traps Induce Autoantigen Production by Airway Epithelial Cells
Choi Y*, Pham LD*, Lee DH, Ban GY, Lee JH, Kim SH, Park HS
Mediators Inflamm, 2017:5675029
6. Gut-Specific Delivery of T-Helper 17 Cells Reduces Obesity and Insulin Resistance in Mice
Hong CP, Park A, Yang BG, Yun CH, Kwak MJ, Lee GW, Kim JH, Jang MS, Lee EJ, Jeun EJ, You G, Kim KS, Choi Y, Park JH, Hwang D, Im SH, Kim JF, Kim YK, Seoh JY, Surh CD, Kim YM#, Jang MH#
Gastroenterology, 152(8):1998-2010
5. Extracellular Vesicles, a Key Mediator to Link Environmental Microbiota to Airway Immunity
Choi Y, Park H, Park HS#, Kim YK#
Allergy Asthma Immunol Res, 9(2):101-106
4. Proteomic analysis of extracellular vesicles derived from Propionibacterium acnes
Jeon J, Mok HJ, Choi Y, Park SC, Jo H, Her J, Han JK, Kim YK, Kim KP, Ban C
Proteomics Clin Appl, 11(1-2)
2015
3. Gut microbe-derived extracellular vesicles induce insulin resistance, thereby impairing glucose metabolism in skeletal muscle
Choi Y, Kwon Y, Kim DK, Jeon J, Jang SC, Wang T, Ban M, Kim MH, Jeon SG, Kim MS, Choi CS, Jee YK, Gho YS, Ryu SH, Kim YK
Sci Rep, 5:15878
2. Active Immunization with Extracellular Vesicles Derived from Staphylococcus aureus Effectively Protects against Staphylococcal Lung Infections, Mainly via Th1 Cell-Mediated Immunity
Choi SJ, Kim MH, Jeon J, Kim OY, Choi Y, Seo J, Hong SW, Lee WH, Jeon SG#, Gho YS, Jee YK, Kim YK#
PLoS One, 10(9):e0136021
1. Phospholipase D2 drives mortality in sepsis by inhibiting neutrophil extracellular trap formation and down-regulating CXCR2
Lee SK, Kim SD, Kook M, Lee HY, Ghim J, Choi Y, Zabel BA, Ryu SH, Bae YS
J Exp Med, 212(9):1381-90