Biosensors and devices lab

2026

1. Jain, K., Kumar, S., Bhat, M. K., Khatoon, Z., Singh, N. K.* A non-invasive nanoengineered CA19.9-based aptasensor for early detection of pancreatic cancer using a smart automated urine analysis system. Biosensors and Bioelectronics: X, 31, 100807 (2026).

 2024

1. Singh, N. K., Wang, Y., Wen, C., Devis, B., Lee, K., Wang, Y. One-step Aptamer Selection in a Three-dimensional Non-fouling Porous Hydrogel. Nature Biotechnology, 42, 1224–1231 (2024). (Impact Factor: 68.16)

2. Bachhu, V., Kuri, P. R., Singh, N. K., Goswami, P. Improving synthesis and binding affinity of nucleic acid aptamers and their therapeutic and diagnostic applications. Biophysical Chemistry, 309 (2024).

2023

1. Singh, N. K., Chung, S., Chang, A.-Y., Wang, J., Hall, D. A. A non-invasive wearable stress patch for real-time cortisol monitoring using a pseudoknot-assisted aptamer. Biosensors and Bioelectronics, 227, 115097 (2023).

 2022

1. Chung, S., Singh, N. K., Hall, D. A. Detection of low therapeutic index carbamazepine drug from undiluted serum and whole blood with a novel conformation-switching aptasensor. ACS Omega, 7(43), 39097–39106 (2022).

2. Das, S., Gogoi, S., Singh, N. K., Goswami, P. Analytical Application of H₂O₂-induced chiroptical graphitic carbon dots. Nano Express (2022).

3. Singh, N. K., Sidhu, G. K., Gupta, K. Current and Future Prospective of Devices and Diagnostics for OIRD. Biomedicines, 10(4), 743 (2022).

4. Ying, D., Rosenberg, J., Singh, N. K., Hall, D. A. A 26.5 pArms Neurotransmitter Front-End with Class-AB Background Subtraction. IEEE Transactions on Biomedical Circuits and Systems (2022).

 2021

1. Singh, N. K., Ray, P., Carlin, A. F., Magallanes, C., Morgan, S., Laurent, L. C., Aronoff-Spencer, E., Hall, D. A. Hitting the diagnostic sweet spot: Point-of-care SARS-CoV-2 salivary antigen testing with an off-the-shelf glucometer. Biosensors and Bioelectronics (2021).

2. Singh, N. K., Ray, P., Carlin, A. F., Magallanes, C., Morgan, S., Laurent, L. C., Aronoff-Spencer, E., Hall, D. A. Dataset on optimization and development of a point-of-care glucometer-based SARS-CoV-2 detection assay using aptamers. Data in Brief, 38, 107278 (2021).

3. Singh, N. K., Sveiven, M., Hall, D. A. A sensitive electrochemical structure-switching aptasensor over an antifouling nanocomposite layer for cortisol detection from undiluted human serum. ACS Omega, 6(42), 27888–27897 (2021).

2020

1. Singh, N. K., Mahato, K. The Contemporaneous and Impending Developments for Combatting COVID-19. Journal of Infectious Diseases and Travel Medicine, 4(1) (2020).

2. Sanjay, M., Singh, N. K., Ngashangva, L., Goswami, P. A smartphone-based fiber-optic aptasensor for label-free detection of Plasmodium falciparum glutamate dehydrogenase. Analytical Methods, 12, 1333–1341 (2020).

 2019

1. Singh, N. K., Jain, P., Das, S., Goswami, P. Dye-coupled aptamer-captured enzyme-catalysed reaction for detection of pan malaria and P. falciparum species in laboratory settings and an instrument-free paper-based platform. Analytical Chemistry (2019).

2. Bhuvanasundar, R., Naresh Kumar, R. N., Singh, N. K., Coral, K., Deepa, P. R., Sulochana, K. N. Expression, purification and characterization of a biologically active and thermally stable human lysyl oxidase. Indian Journal of Biochemistry and Biophysics, 56, 105–116 (2019).

 2018

1. Singh, N. K., Arya, S. K., Estrela, P., Goswami, P. Capacitive malaria aptasensor using Plasmodium falciparum glutamate dehydrogenase as target antigen in undiluted human serum. Biosensors and Bioelectronics, 117, 246–252 (2018).

2. Singh, N. K., Chakma, B., Jain, P., Goswami, P. Protein-induced fluorescence enhancement based detection of P. falciparum glutamate dehydrogenase using carbon dot-coupled specific aptamer. ACS Combinatorial Science, 20(6), 350–357 (2018).

3. Singh, N. K., Thungoan, P. D., Estrela, P., Goswami, P. Development of an aptamer-based BioFET sensor for quantitative detection of Plasmodium falciparum glutamate dehydrogenase in serum samples. Biosensors and Bioelectronics, 123, 30–35 (2018).

4. Chakma, B., Jain, P., Singh, N. K., Goswami, P. Development of Electrochemical Impedance Spectroscopy Based Malaria Aptasensor Using HRP-II as Target Biomarker. Electroanalysis (2018).

 2017

1. Jain, P., Chakma, B., Singh, N. K., Patra, S., Goswami, P. Metal-DNA interactions improve signal in high-resolution melting of DNA for species differentiation of Plasmodium parasite. Molecular Biotechnology, 59(6), 179–191 (2017).

2016

1. Gupta, K., Dhawan, R., Kajla, M., Jnanasiddhy, B., Singh, N. K., Gupta, L. Molecular Identification and Colonization of Yellow Fever Mosquito Aedes aegypti Isolated from Rajasthan Region, India. Journal of Vector Borne Diseases, 53(2), 149–155 (2016).

2. Santhosh, M., Chinnadayyala, S. R., Singh, N. K., Goswami, P. Human serum stabilized gold nanoclusters act as electron transfer bridges supporting specific electrocatalysis of bilirubin useful for biosensing application. Bioelectrochemistry, 111, 7–14 (2016).

3. Jain, P., Chakma, B., Singh, N. K., Goswami, P. Aromatic Surfactant as Aggregating Agent for Aptamer-Gold Nanoparticle-Based Detection of Plasmodium Lactate Dehydrogenase. Molecular Biotechnology, 58(7), 497–508 (2016).

4. Chakma, B., Jain, P., Singh, N. K., Goswami, P. Development of Indicator Displacement Based Detection of Malaria Targeting HRP-II as Biomarker for Point-of-Care and Analytical Applications. Analytical Chemistry, 88(20), 10316–10321 (2016).

 2015

1. Chinnadayyala, S. R., Santhosh, M., Singh, N. K., Goswami, P. Alcohol oxidase protein-mediated in-situ synthesized and stabilized gold nanoparticles for developing an amperometric alcohol biosensor. Biosensors and Bioelectronics, 69, 155–161 (2015).

 Database

1. Bachu, V., Deware, L., Kumar, A., Kuri, P. R., Mili, M., Singh, N. K., Goswami, P. APTABASE: Database for Global Aptamers.

​

Patents

1. DNA aptamers specifically binding to Plasmodium falciparum glutamate dehydrogenase (PfGDHa) [Patent Application No.201631025722].

2. A novel syringe design to facilitate instrument free Detection of NADP/NAD+ based enzymatic reactions in paper platform following optical signal [Patent Application No. 201831030902 Dated 17.08.2018].

3. Optisense - A Smartphone-based multi-channel, static LSPR system using U-bent plastic optic fibre probes for point-of-care diagnosis or telediagnosis. [Patent Application No. 201931039853 Dated 03.10.2019]

4. An aptamer based point of care test for COVID-19 using a glucometer [US Patent- Application submitted,   UCSD Docket/Case No. SD2021-018].

5. One-step Aptamer Selection in a Three-dimensional Non-fouling Porous Hydrogel [U. S. Serial No. 63/428,466, Docket No. PSU 2022-5492]

6. FLUID DISPENSING DEVICE AND ASSEMBLY, Urosmart, application number 202611003292. IIT Delhi

7. TOHFA_GM: A Tear-Oriented Metal Hybrid Framework-Based Analyser for Non-Invasive, Non-Enzymatic Point-of-Care Glucose Monitoring Application number- FT/IDF/9/2025/137). 

Book chapter

1. Carbon based nanomaterial and carbon dots  for sensing application, Advance Materials and Techniques for Biosensors and Bio analytical Applications, CRC Press; 1 edition (15 Nov. 2020)

2.  Enzymatic biosensor platforms for non-infectious diseases: Diagnostics of metabolic disorders, Enzyme-based biosensors: Recent advance and application in healthcare. Springer publishing house, (Under Editing)

3. Recent trends in clinical diagnosis for viral disease detection based on miniaturized biosensors, Elsevier publishing house, Naveen K Singh, Himali horo, Vikky Rajulpati