Biopharmaceuticals are medicinal products derived from biological sources mainly macromolecules. The drugs especially are produced using biotechnology. They are used for therapeutics, especially cell and gene therapy, prophylactics and in vivo diagnostics including antibodies, peptides and nucleic acids (DNA and RNA). Biopharmaceuticals' production employs modern biotechnological tools like recombinant DNA and hybridoma technologies, which are carried out in engineered biological systems. Additionally, genetically modified transgenic organisms are also used potentially to produce biopharmaceuticals.
Recent advances in the field of biotechnology have facilitated the utilisation of such technologies to produce various biopharmaceuticals, which could exceed more than half of the total number of new pharmaceuticals produced. Since biopharmaceutical products have successfully entered the market, the U.S Food and Drug Administration had approved 18 new biopharmaceutical products in 2012. Among the approved, 18 were recombinant proteins, including two monoclonal antibodies.
This is a student-made platform for the subject FAR 247/2 Biopharmaceuticals II, Bachelor of Pharmacy, School of Pharmaceutical Sciences, Universiti Sains Malaysia which contains comprehensive information of top selling biopharmaceuticals. The information has also been depicted in the form of infographics.