Chittabrata Mal, Ph.D

chittabrata[dot]mal[at]makautwb[dot]ac[dot]in

Professional Experience:

November 2023 to Present: Associate Professor, Department of Bioinformatics, MAKAUT, WB

July 2021 to October 2023: Assistant Professor, Department of Bioinformatics, MAKAUT, WB

August 2015 to July 2021: Assistant Professor, Institute of Biotechnology, Amity University Kolkata

April 2015 to August 2015: Intern, National Institute of Biomedical Genomics, India.

Education:

2009 - 2015: PhD in Genetics, Molecular Biology and Bioinformatics from University of Calcutta.

2006 - 2008 : MSc in Biotechnology from University of Burdwan.

2003 - 2006 : BSc(H) in Biotechnology from University of Burdwan.

Awards:

Advanced Internship in Computational Biology, National Institute of Biomedical Genomics, India in 2015.
Senior Research Fellowship, DST-PURSE, Department of Science and Technology, Govt. of India in 2014.
Senior Research Fellowship, University Grant Commission, Research Fellowship for Meritorious Students in Science (RFSMS), Govt. of India in 2011.
Junior Research Fellowship, University Grant Commission, Research Fellowship for Meritorious Students in Science (RFSMS), Govt. of India in 2009.
National Merit Scholarship for 42th rank in Madhyamik examination, National Merit Scholarship, Govt. of West Bengal, India in 2001.

Research Interests:

Computational Biology; Gene Expression; Small RNAs; Functional Genomics; Microbiome; Biomarker; Machine learning

Lab Members:

Present:

Ankit Pal, Prashikha from Department of Bioinformatics, MAKAUT, WB

Past:

Debangana Chakrabarti, Madhura Das, Sagnik Nag, Ayoshi Mitra, Shrayan Ghosh, Sayam Porey, Rajeswari Shil, Rajdeep Ghosh, Ayushman Kumar Banerjee from Amity University Kolkata (Project Trainee)
Arunava Banerjee, Arnab Mondal, Navonil Mal from University of Calcutta (Project Trainee)
Srijoni Sen from BIT, MESRA (Project Trainee)
Sayani Nandi, Aritra Palodhi, Ayushman Kumar Banerjee, Subhadip Das, Debarghya, Ananya from Department of Bioinformatics, MAKAUT, WB
Shruti Hazra, Joyeta Dey, Suchismita Mukherjee, Sucheta Mondal, Shankhadeep Bar, Disha Roy from Department of Biotechnology, MAKAUT, WB

Publications: Google scholar link

Publications (Peer reviewed Articles):

Sanyal, D., AlShahrani, A. M., Kar, S., Ahmad, S. R., Chittabrata Mal, & Mondal, S. K. (2025). Decoding molecular signatures and identifying therapeutic targets in triple-negative breast cancer subtypes using omics and network analysis. Scientific Reports, 15(1), 44469.
Ghosh, J., Alshahrani, A. M., Palodhi, A., Bhattacharyya, D., Das, S., Mondal, S. K., ... & Chittabrata Mal (2025). Identification and therapeutic investigation of biomarker genes underpinning hepatocellular carcinoma: an in silico study utilising molecular docking and dynamics simulation. Frontiers in Bioinformatics, 5, 1567748.
Bera, P., Debnath, S., Chittabrata Mal, & Mondal, S. K. (2025). Integrating relieff-based feature selection and ensemble machine learning for robust biomarker identification in colorectal cancer. Network Modeling Analysis in Health Informatics and Bioinformatics, 14(1), 40.
Chatterjee, A., Palodhi, A., Basnet, H., Agarwal, P., Das, B. K., Chittabrata Mal, & Pal, H. (2025). Understanding the Therapeutic Potential of Smilax perfoliata and Elsholtzia griffithii Through GC-MS Analysis, Antimicrobial Assay and Molecular Docking. Plant Foods for Human Nutrition, 80(2), 1-8.
Kordkatouli, M., Cho, W. C., Janlou, M. A. M., Sateei, A., Heidari, M., Mal, C., ... & Urbonas, V. (2025). A review on the role of microRNA-340 and curcumin in apoptosis and metastasis in colorectal cancer. Journal of HerbMed Pharmacology., 14(3), 277-291.
Das, S., Bhattacharyya, D., Arshad, M., & Chittabrata Mal (2024). The potential of the NLRC4 Inflammasome as a Cancer biomarker: A Pan-cancer investigation. Human Gene, 201351.
A Mitra, S Ghosh, S Porey, Chittabrata Mal (2023) GBP5 and ACSS3: two potential biomarkers of high-grade ovarian cancer identified through downstream analysis of microarray data. Journal of Biomolecular Structure and Dynamics, 1-13
Chittabrata Mal, Banerjee, A. K., & Mal, J. (2022, December). Genome Scale Pathway-Pathway Co-functional Synergistic Network (PcFSN) in Oryza Sativa. In conference BioSangam 2022: Emerging trends in Biotechnology (BIOSANGAM 2022) (pp. 47-57). Atlantis Press.
R Shil, R Ghosh, AK Banerjee, Chittabrata Mal (2022) LncRNA, miRNA and transcriptional co-regulatory network of breast and ovarian cancer reveals hub molecules. Meta Gene, 101024
Z Ahmed, Chittabrata Mal (2021) Functional role of hub molecules in miRNA and transcription factor mediated gene regulatory network of colorectal and lung cancer. Gene Reports 23, 101129
A Biswas, B Sen, S Bandyopadhyay, Chittabrata Mal (2021) Co-regulatory functions of miRNA and lncRNA in adapting biotic and abiotic stress in economically important dicot plants. Plant Gene 26, 100275
AK Banerjee , Chittabrata Mal (2020) Underpinning miRNA-miRNA co-functional interaction patterns in metabolism of Oryza sativa by genome-scale network analysis . Heliyon 6 (11), e05496
S Das, N Jahan, Chittabrata Mal (2020) In-silico Identification of lncRNA Functionality in Cancers Related to Obesity. International Journal of BioSciences & Technology 13 (3)
AK Banerjee , R Bhattacharya , Chittabrata Mal (2020) HMG2D: A tool to identify miRNAs/drugs/genes associated with diseases like cancers. Meta Gene, 100699
S Bhattacharya , A Banerjee , PP Sah, Chittabrata Mal, S Ray (2018) Mutations and functional analysis of 14-3-3 stress response protein from Triticum aestivum: An evolutionary analysis through in silico structural biochemistry approach. Computational Biology and Chemistry, 77:343-353
Chittabrata Mal, Md. Aftabuddin, & Sudip Kundu (2018). Inter and Intra Kingdom miRNA Target Analyzer (IIKmTA). Interdisciplinary Sciences: Computational Life Sciences, doi: 10.1007/s12539-018-0291-6
Chittabrata Mal, & Sudip Kundu (2018). Comparative study on Sequence Characteristics of Mature and Precursor miRNAs of Monocot and Dicot plants. Indian Journal of Biotechnology. Indian Journal of Biotechnology. 17(3):520-526
Chittabrata Mal and Ayan Raichaudhuri (2017). Role of Rice miRNAs in Pathogen Response. EC Microbiology 13.2: 67-75.
Chittabrata Mal, Arindam Deb, Md. Aftabuddin, & Sudip Kundu (2015). A network analysis of miRNA mediated gene regulation of rice: crosstalk among biological processes. Mol. BioSyst., 11(8):2273-80
Chittabrata Mal, Md. Aftabuddin, & Sudip Kundu (2014). No3CoGP: non-conserved and conserved coexpressed gene pairs. BMC research notes 7(1) , 886.
Md. Aftabuddin, Chittabrata Mal, Arindam Deb, & Sudip Kundu (2014). C2Analyzer: Co-target Co-function Analyzer. Genomics, Proteomics & Bioinformatics 12(3): 133-136.
Chittabrata Mal, Arindam Deb, Md. Aftabuddin, & Sudip Kundu (2013). miRNA Mediated Regulation of Rice (Oryza sativa) Genome ∗ appeared in 12th IFAC Symposium on Computer Applications in Biotechnology.

Publications (Book Chapters):

Mahata, K., Sengupta, S., Biswas, M., Ghosh, S., Banerjee, A. K., Pati, S. K., & Chittabrata Mal (2025). Application of Machine Learning in Bioinformatics: Capture and Interpret Biological Data. In Machine Learning in Biomedical and Health Informatics (pp. 239-262). Apple Academic Press.
Chakraborty, D., Roy, P. K., Das, R., & Chittabrata Mal (2025). Personalized management of Parkinson's disease. Progress in Brain Research, 297, 277-318.
Sen, A., Roy, S., Choudhury, P., Ghosh, S., Chittabrata Mal, & Bhattacharya, S. (2024). Exploring the potential of nanozyme-assisted abiotic stress resilience in crop plants as an emerging technique for sustainable agriculture. In Nanotechnology for Abiotic Stress Tolerance and Management in Crop Plants (pp. 203-214). Academic Press.
Banerjee, A. K., Ghosh, S., & Chittabrata Mal (2023). Identification of Culprit Genes for Different Diseases by Analyzing Microarray Data. In Reverse Engineering of Regulatory Networks (pp. 167-180). New York, NY: Springer US.
Hazra, S., Dey, J., Mukherjee, S., Kalam, A., & Chittabrata Mal (2023). Identification of Novel Microbial Strains for Reduced Pesticide Use in Millets. In Millet Rhizosphere (pp. 97-120). Singapore: Springer Nature Singapore.
Mondal, S., Bar, S., Roy, D., Hazra, S., Mal, J., Bilal, M., & Chittabrata Mal (2022). Genetic Engineering Strategies and Degradation of Pollutants Using Genetically Engineered Microorganisms (GEMs). In Biotechnology for Environmental Protection (pp. 209-232). Singapore: Springer Nature Singapore.
Dhar, S., Selvasembian, R., Sharma, R., Singh, P., Chittabrata Mal, Mishra, A. K., & Mal, J. (2022). Biogenic Synthesis of Nanoparticles and Its Application in Wastewater Treatment. In Biotechnology for Environmental Protection (pp. 233-255). Singapore: Springer Nature Singapore.
Navonil Mal and Chittabrata Mal (2022) Abiotic stress tolerant small millet plant growth regulation by long noncoding RNAs: an omics perspective, Omics of Climate Resilient Small Millets, Springer Nature
Chittabrata Mal (2021) Understanding Explainable AI: Role in IoT-Based Disease Prediction and Diagnosis, Medical Internet of Things: Techniques, Practices and Applications, CRC Press 205

Publications (Conference Presentations):

1. International Conference on Translational Research: Applications in Human Health and Agriculture, Amity University Kolkata, from 23rd- 25th September, 2017.

Presented poster: MPIA-MicroRNA and Pathway Integrated Analyzer.

2. National Symposium on "Exploring Biological Systems: Cell to Organism" , University of Calcutta, from March 1-3, 2016.

Presented poster: SNBA - Synergistic Network Builder and Analyzer.

3. Annual Conference of Indian Biophysical Society entitled “Molecular Architecture, Dynamics and Assembly in Living Systems (MADALS 2014)”, SINP, Kolkata, India from 7-10 February, 2014.

Presented poster: Conserved and Non-conserved Gene Pairs in Different Tomato.

4. International conference on “Plant and Animal Genome Asia (PAG ASIA2013)”, Singapore from 17 -19 March, 2013.

Presented poster: Impingement of miRNAs During Biotic and Abiotic Stress on Metabolic Pathways of Rice.

5. International Symposium on “Plant Biotechnology Towards Tolerance to Stresses and Enhancing Crop Yield”, BIT, Jharkhand, India from Sept 28 - Oct 1, 2011.

Presented poster: Analyzing miRNA co-targeting network in rice.

6. Silver Jubilee Symposium on Bioinformatics - BTISNET in India (1986-2011), Pondicherry University, Pondicherry, India on February 2, 2011.

Presented poster: Potential impact of miR co-targeting network and miR-Loci-TF interaction in rice.

Research Areas in brief

Dr. Chittabrata Mal’s research centers on computational and systems-level analysis of complex biological data, with a strong emphasis on cancer bioinformatics and regulatory genomics. His recent work focuses on the integrative analysis of transcriptomic and microarray datasets to identify diagnostic and prognostic biomarkers, investigate inflammasome signaling and immune-related genes across multiple cancer types, and elucidate miRNA–lncRNA–mRNA regulatory networks involved in disease progression. The lab is particularly interested in applying network biology, functional genomics, machine learning and pan-cancer analyses to uncover molecular mechanisms underlying cancer and other complex diseases, with the broader goal of supporting precision medicine and translational research.

Page updated

Google Sites

Report abuse