AMAURY BADON
CNRS researcher
email : amaury(dot)badon(at)cnrs(dot)fr
Optical imaging is crucial for life science to study, understand and reveal new structures or phenomena. Recently, multi-cellular aggregates that mimics in vitro and in 3D some functions of organs (organoids) emerged as new biological models. Even if remarkable efforts have been made to adapt existing tools to image developing multicellular aggregates, current solutions are insufficient to observe the spatiotemporal organization of such samples over days or weeks in non-invasive manner.
My objective is to develop new imaging techniques or modalities dedicated to the non-invaisve observation of organoids.
We recently developped a method that combines electrical and mechanical control of the fragmentation of a jet into droplets for producing monodisperse and tunable hydrogel capsules for 3D cell culture.
Light-field microscopy (LFM) offers instantaneous 3D imaging by capturing both spatial and angular information from a semi-transparent specimen. We aim to push back the current limits of LFM both in terms of depth and imaging volumes by combining innovative experimental and numerical approaches.
Postdoctoral scientists :
Charlie Kersuzan
PhD students :
Aymerick Bazin (100 %)
Anirban Jana (20 %)
Lucas Suire (50 %)
Théo Regny (50 %)
A Bazin, A Badon
Increasing the spatial bandwidth product in Light Field Microscopy with remote scanning., Biomedical Optics Express 16 (3), 1062-1070
A. Badon , S. Bensussen, H. J. Gritton, M. R. Awal, C. V. Gabel, X. Han and J. Mertz.
Video-rate large scale imaging with Multi-Z confocal microscopy, Optica 6 (4), 389-395
G. Recher, P. Nassoy, A. Badon ,
Remote scanning for ultra-large field of view in wide-field microscopy and full-field OCT , Biomedical Optics Express 11 (5), 2578-2590
A. Badon , V. Barolle, G. Lerosey, A. C. Boccara, M. Fink, A. Aubry.
Distortion matrix concept for deep imaging in scattering media, Science Advances 6 (30), eaay7170
A. Badon , L. Andrique, A. Mombereau, L. Rivet, A. Boyreau, P. Nassoy, G. Recher.
The Incubascope: a simple, compact and large field of view microscope for long-term imaging inside an incubator, Royal Society Open Science 9 (2)
A. Badon , G. Lerosey, A. C. Boccara, M. Fink, A. Aubry.
Retrieving time-dependent Green’s functions in optics with low-coherence interferometry, Physical Review Letters 114 (2), 023901 (IF 8.839)