VIPA-based Brillouin spectrometer

We have implemented two Brillouin spectrometers based on a virtually imaged phased array (VIPA) that relies on the analysis of a beam focused onto a fixed etalon, resulting in the angular dispersion of the spectrum that can then be recorded by a CCD array. This solution enables acquisition times shorter than 0.1 ms, making it particularly attractive for high-throughput applications. We have a commercial setup from Light Machinery (Hyperfine HF-8999-660) and a home-made device.

Life Science microscope

We have developed a confocal life science microscope that allows maintaining temperature and CO2 levels to investigate the dynamics of cells and tissues over several days. We have coupled it with the Brillouin spectrometers to probe the role of mechanics in the resistance of tumors to therapy, and to analyze mineralized tissues.

Transient Grating Spectroscopy

Transient Grating Spectroscopy (TGS) is a time-resolved optical technique in which ultrashort laser pulses are crossed in the sample, forming a periodic optical interference pattern whose dynamics can be monitored via diffraction of a cw probe laser. We use TGS to characterize and measure the acoustic, mechanical, and thermal transport properties of a variety of materials systems, including microstructured, anisotropic, biological, thin films, and glass composite systems.

Laser Ultrasonics characterization

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We utilize pulsed and continuous laser sources, combined with a variety of optical setups to generate and detect various types of ultrasonic waves in solids, liquids, and biological media. This includes longitudinal and shear Bulk Acoustic Waves (BAWs) as well as Guided and Surface Acoustic Waves (GAWs and SAWs) over a broadband MHz frequency range spanning three decades (from 1 MHz to 1 GHz). We utilize versatile optical interferometers and photo-deflection-based schemes, coupled with optical and fluorescence microscopes, to probe this high frequency wave-matter interaction with microscale resolution, in a non-contact and non-invasive manner.

Shared Access

Image analysis by deep learning or machine learning
Potts models
Microfluidics
4D Traction Force Microscopy
In-situ immostaining and imaging of spheroids
Molecular biology
Micro- and Nanofabrication platform at Institut des Nanotechnologies de Lyon (INL)
learn more about our shared equipment here

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