Dissemination
Publications
L.-M. Daian, G. Tanko, A. Vacaru, E. Lamba, O.-M. Mardare, A.-M. Vacaru. Uncovering the secrets of beta cells: targeted ablation of cellular mass as a model of stress. Diabetologia, 2023, 66 (Suppl 1): S233. https://link.springer.com/article/10.1007/s00125-023-05969-6#Sec1
E.-M. Lamba, G. Tanko, O.-A. Mardare, L.M. Daian, A.M. Vacaru, A.-M. Vacaru. Assessing variation of beta cells heterogeneity during diabetes progression. Diabetologia, 2023, 66 (Suppl 1): S240. https://link.springer.com/article/10.1007/s00125-023-05969-6#Sec1
Daian LM, Tanko G, Vacaru AM, Ghila L, Chera S and Vacaru A-M. Modulation of Unfolded Protein Response Restores Survival and Function of β-Cells Exposed to the Endocrine Disruptor Bisphenol A. International Journal of Molecular Sciences, 2023, 24(3). https://doi.org/10.3390/ijms24032023
Vacaru AM, Mazilu A-M, Dumitrescu M, Fenyo IM, Gafencu AV and Vacaru A-M. Treatment with Mesenchymal Stromal Cells Overexpressing Fas-Ligand Ameliorates Acute Graft-versus-Host Disease in Mice. International Journal of Molecular Sciences, 2022, 23(1), 534. https://doi.org/10.3390/ijms23010534
Lenghel A, Gheorghita AM, Vacaru AM and Vacaru A-M. What Is the Sweetest UPR Flavor for the β-cell? That Is the Question. Frontiers in Endocrinology. 2021 Jan 19; 11:614123. https://doi.org/10.3389/fendo.2020.614123
Meetings
Oral presentations
23.11.2023 - Elena Mirela Lamba - "Impact of increased dietary glucose intake on β-cells functional heterogeneity" - FEBS - IUBMB - ENABLE 2nd International Molecular Biosciences PhD and Postdoc Conference, Cologne, Germany
23.11.2023 - Oana-Ana-Maria Mardare - "Changes induced in murine β-cells by pharmacological UPR activation" - FEBS - IUBMB - ENABLE 2nd International Molecular Biosciences PhD and Postdoc Conference, Cologne, Germany
23.11.2023 - Sabin Popa - "Dynamics of the physiological parameters during the prediabetic states of a murine model of diabetes" - FEBS - IUBMB - ENABLE 2nd International Molecular Biosciences PhD and Postdoc Conference, Cologne, Germany
16.11.2023 - Ana Vacaru - “Supportive therapy for diabetes by increasing the stress endurance and regenerative capacity of β-cells” - The 44th Annual Scientific Symposium of the Institute of Cellular Biology and Pathology "Nicolae Simionescu" held jointly with the 40th Annual Scientific Session of the Romanian Society for Cell Biology, Bucharest, Romania
04.10.2023 - Elena Lamba - "Assessing variation of beta cells heterogeneity during diabetes progression" - 59th Annual Meeting of the European Association for the Study of Diabetes, Hamburg, Germany
03.10.2023 - Laura Daian - "Uncovering the secrets of beta cells: targeted ablation of cellular mass as a model of stress" - 59th Annual Meeting of the European Association for the Study of Diabetes, Hamburg, Germany
09.12.2022 - Ana Vacaru - "Stress models to study the impact of UPR activation on β-cells fate" - Institute of Cellular Biology and Pathology "Nicolae Simionescu" Annual Scientific Symposium with international participation held under the aegis of the Romanian Academy, Bucharest, Romania
05.11.2021 - Laura Daian - "Living under stress - Evaluating changes in β cells homeostasis" - The 42nd Anniversary Symposium of the Institute of Cellular Biology and Pathology "Nicolae Simionescu" and the 38th Annual Scientific Session of the Romanian Society for Cell Biology, Bucharest, Romania
04.11.2021 - Ana Vacaru - BETAUPREG project presentation - The 42nd Anniversary Symposium of the Institute of Cellular Biology and Pathology "Nicolae Simionescu" and the 38th Annual Scientific Session of the Romanian Society for Cell Biology, Bucharest, Romania
Posters
Laura-Maria Daian, Andrei Mircea Vacaru, Elena Mirela Lamba, Oana Ana-Maria Mardare, Andrei-Sabin Popa, Luiza Ghila, Simona Chera, Ana Maria Vacaru. "From plate to pancreas: High fat diets and their impact on stressed β-cells" - FEBS - IUBMB - ENABLE 2nd International Molecular Biosciences PhD and Postdoc Conference, 23-25 November 2023, Cologne, Germany
Oana-Ana-Maria Mardare, Elena Mirela Lamba, Laura-Maria Daian, Andrei Mircea Vacaru, Luiza Ghila, Simona Chera, Ana Maria Vacaru. “Induction of Insulin Dysfunction in Murine β-Cells Through Pharmacological Activation of UPR” - The 44th Annual Scientific Symposium of the Institute of Cellular Biology and Pathology "Nicolae Simionescu" held jointly with the 40th Annual Scientific Session of the Romanian Society for Cell Biology, 16-17 November 2023, Bucharest, Romania
Elena Mirela Lamba, Gabriela Tanko, Oana-Ana-Maria Mardare, Laura-Maria Daian, Andrei Mircea Vacaru, Ana Maria Vacaru. “Assessing variation of β-cells heterogeneity during diabetes progression” - The 44th Annual Scientific Symposium of the Institute of Cellular Biology and Pathology "Nicolae Simionescu" held jointly with the 40th Annual Scientific Session of the Romanian Society for Cell Biology, 16-17 November 2023, Bucharest, Romania
Laura-Maria Daian, Andrei Mircea Vacaru, Elena Mirela Lamba, Oana-Ana-Maria Mardare, Andrei-Sabin Popa, Ana Maria Vacaru. “Exploring the stress response in pancreatic β-cells by selective ablation of cellular mass: a model analysis” - The 44th Annual Scientific Symposium of the Institute of Cellular Biology and Pathology "Nicolae Simionescu" held jointly with the 40th Annual Scientific Session of the Romanian Society for Cell Biology, 16-17 November 2023, Bucharest, Romania
Laura Maria Daian, Gabriela Tanko, Andrei Mircea Vacaru, Ana Maria Vacaru. "Endocrine disruptor bisphenol A impairs β-cells viability and function by activating a pro-apoptotic UPR". INSTITUTE OF CELLULAR BIOLOGY AND PATHOLOGY “NICOLAE SIMIONESCU” ANNUAL SCIENTIFIC SYMPOSIUM with international participation held under the aegis of the ROMANIAN ACADEMY, 8-9 December 2022, Bucharest, Romania
Alina Lenghel, Ana Maria Vacaru. “Hero or villain? The effect of pharmacological UPR activation on a murine β-cell line”. European Islet Study Group Workshop, 13-15th June 2022, Strasbourg, France
Laura Maria Daian, Andrei Mircea Vacaru, Ana Maria Vacaru. “Restoring unfolded protein response homeostasis preserves survival and function of β-cells exposed to the endocrine disruptor bisphenol A”. European Islet Study Group Workshop, 13-15th June 2022, Strasbourg, France
Luiza Ghila, Thomas Aga Legøy, Shadab Abadpour, Paolo Joao, Hanne Scholz, Simona Chera, “Exploring the unfolded protein response signature in human islet proteome”. European Islet Study Group Workshop, 13-15th June 2022, Strasbourg, France
Laura Maria Daian, Gabriela Tanko, Andrei Mircea Vacaru, Ana Maria Vacaru. "Endocrine disruptor bisphenol A impairs β-cells viability and function by activating a pro-apoptotic UPR". INSTITUTE OF CELLULAR BIOLOGY AND PATHOLOGY “NICOLAE SIMIONESCU” ANNUAL SCIENTIFIC SYMPOSIUM with international participation held under the aegis of the ROMANIAN ACADEMY, 8-9 December 2022, Bucharest, Romania