Amytal Sodium is a medication that contains amobarbital sodium as its active ingredient. It is administered as a lyophilized powder for injection, typically in vials containing 500 mg of amobarbital sodium. The medication is used as a sedative and hypnotic to promote relaxation and sleepiness.

It works by suppressing the activity of the central nervous system, which includes the brain and spinal cord, and promoting the effects of the neurotransmitter gamma-Aminobutyric acid (GABA), which serves to slow down nerve impulses in the brain. Amytal Sodium is a non-selective central nervous system (CNS) depressant belonging to the class of drugs known as barbiturates.

It is essential to consult with a licensed healthcare professional before using the medication to get accurate prescription and usage information as it has several potential risks and side effects, including respiratory depression, hypotension, and habit forming.



Amytal sodium, also known as Amobarbital is a drug that is a barbiturate derivative. It has sedative-hypnotic properties. It is a white crystalline powder with no odor and a slightly bitter taste. It was first synthesized in Germany in 1923. It is considered a short to intermediate acting barbiturate. Wikipedia

Metabolism: Hepatic

Routes of administration: Oral, IM, IV, Rectal

AHFS/Drugs.com: Micromedex Detailed Consumer Information

ChemSpider: 2079

Elimination half-life: 8–42 hours

Excretion: Renal

PubChem CID: 2164

Amytal Sodium injectable powder for injection 500 mg