PUBLICATIONS

PEER-REVIEWED JOURNAL ARTICLES/BOOK CHAPTERS

dagger sign(+) represents equal contribution; asterisk (*) represents corresponding author; my name is underlined.

Submitted/In Preparation

2025

Comparative stabilization mechanism of self-assembling fattigated gelatin, micellar polyethylene glycol hexadecyl ether, and electrostatic interactive xanthan gum for aqueous labile decitabine

SM Lee, H Van Ngo, HD Nguyen, MC Gil, JB Park, C Park, Van Hong Nguyen, Gang Jin, Beom-Jin Lee

Enhanced and Prolonged Immunogenicity in Mice of Thermally Stabilized Fatty Acid-Conjugated Vaccine Antigen

BM Kim, YH Kim, HV Ngo, HD Nguyen, C Park, BJ Lee

Release-modulating mechanism and comparative pharmacokinetics in beagle dogs of bethanechol-loaded oral dosage forms

HM Jeong, H Kim, T Jang, A Choi, JB Park, C Park, BJ Lee

Current advances and future perspectives of fattigation technology in pharmaceutical sciences and drug delivery

HV Ngo, HD Nguyen, C Park, VH Nguyen, BJ Lee

2024

Novel First-Generation Dissolution Models to Investigate the Release and Uptake of Oral Lymphotropic Drug Products

M Yousef, C Park, NB Chacra, NM Davies, R Löbenberg

Current advances and future perspectives of fattigation technology in pharmaceutical sciences and drug delivery

HV Ngo, HD Nguyen, C Park, VH Nguyen, BJ Lee

Journal of Pharmaceutical Investigation, 1-18

Advancements of hot-melt extrusion technology to address unmet patient needs and pharmaceutical quality aspects

C Park, VS Renuka, BJ Lee, I de la Peña, JB Park

Journal of Pharmaceutical Investigation, 1-18

Self-assembled nanonization of fatty acid-conjugated vaccine antigen for enhanced thermal stability

YH Kim, C Park, HD Nguyen, HV Ngo, BJ Lee

International Journal of Pharmaceutics 658, 124176

In Vitro Predictive Model for Intestinal Lymphatic Uptake: Exploration of Additional Enhancers and Inhibitors

M Yousef, C O’Croinin, TS Le, C Park, J Zuo, N Bou Chacra, NM Davies, ...

Pharmaceutics 16 (6), 768

Improved Transdermal Delivery of Novel Cannabinoid-Loaded Patches Using Eudragit Matrix

E Wongwad, K Ingkaninan, N Waranuch, C Park, V Somayaji, N Na-Ek, ...

Journal of Drug Delivery Science and Technology, 105697

Nanonization and Deformable Behavior of Fattigated Peptide Drug in Mucoadhesive Buccal Films

W Kim, HV Ngo, HD Nguyen, JM Park, KW Lee, C Park, JB Park, BJ Lee

Pharmaceutics 16 (4), 468

2023

Polyelectrolyte-based solid dispersions for enhanced dissolution and pH-Independent controlled release of sildenafil citrate

JH Woo, HV Ngo, HD Nguyen, MC Gil, C Park, JB Park, JH Cui, QR Cao, ...

Heliyon 9 (12)

Investigation of Cannabinoid Acid/Cyclodextrin Inclusion Complex for Improving Physicochemical and Biological Performance

C Park, J Zuo, MC Gil, R Löbenberg, BJ Lee

Pharmaceutics 15 (11), 2533

Development of a Novel In Vitro Model to Study Lymphatic Uptake of Drugs via Artificial Chylomicrons

M Yousef, C Park, M Henostroza, N Bou Chacra, NM Davies, ...

Pharmaceutics 15 (11), 2532

Cellular Efficacy of Fattigated Nanoparticles and Real-Time ROS Occurrence Using Microfluidic Hepatocarcinoma Chip System: Effect of Anticancer Drug Solubility and Shear Stress

H Kim, EJ Kim, HV Ngo, HD Nguyen, C Park, KH Choi, JB Park, BJ Lee

Pharmaceuticals 16 (9), 1330

Development of fixed-dose combination with dual-release properties using double-melt extrusion technology

HK Seo, C Park, HS Oh, IH Park, CY Kang, BJ Lee, I de la Peña, KY Weon, ...

Journal of Drug Delivery Science and Technology 87, 104809

Physicochemical and Biopharmaceutical Controllability of New Self-Assembled Fatty Acid Conjugated Leuprolide for the Enhanced Anticancer Activity

HV Ngo, HE Bak, HD Nguyen, KW Lee, C Park, BJ Lee

International Journal of Nanomedicine, 2325-2344

Mucoadhesive buccal tablet of leuprolide and its fatty acid conjugate: Design, in vitro evaluation and formulation strategies

H Jin, HV Ngo, C Park, BJ Lee

International Journal of Pharmaceutics 639, 122963

Dual thermal stabilizing effects of xanthan gums via glycosylation and hydrogen bonding and in vivo human bioavailability of desmopressin in orodispersible film

MC Gil, SJ Park, BS Lee, C Park, BJ Lee

International Journal of Pharmaceutics 637, 122879

Biphasic dissolution combined with modified cylinder method—A new promising method for dissolution test in drug-loaded nanoemulsions

MN Yukuyama, J Zuo, C Park, M Yousef, MAB Henostroza, GLB de Araujo, ...

International Journal of Pharmaceutics 632, 122554

Sub-cellular sequestration of alkaline drugs in lysosomes: new insights for pharmaceutical development of lysosomal fluid

M Yousef, TS Le, J Zuo, C Park, NB Chacra, NM Davies, R Löbenberg

Research in Pharmaceutical Sciences 18 (1), 1

2022

Investigation of patient-centric 3D-printed orodispersible films containing amorphous aripiprazole

JH Lee, C Park, IOK Song, BJ Lee, CY Kang, JB Park

Pharmaceuticals 15 (7), 895

Release kinetics of hydroxypropyl methylcellulose governing drug release and hydrodynamic changes of matrix tablet

C Park, JH Lee, G Jin, HV Ngo, JB Park, TTD Tran, PHL Tran, BJ Lee

Current Drug Delivery 19 (5), 520-533

Design and evaluation of in vivo bioavailability in beagle dogs of bilayer tablet consisting of immediate release nanosuspension and sustained release layers of rebamipide

G Jin, HV Ngo, J Wang, JH Cui, QR Cao, C Park, M Jung, BJ Lee

International Journal of Pharmaceutics 619, 121718

Electrostatic molecular effect of differently charged surfactants on the solubilization capacity and physicochemical properties of salt-caged nanosuspensions containing pH …

G Jin, HV Ngo, J Wang, JH Cui, QR Cao, C Park, BJ Lee

International Journal of Pharmaceutics 619, 121686

Simulated Lymphatic Fluid for In-Vitro Assessment in Pharmaceutical Development

M Yousef, C Park, TS Le, NB Chacra, NM Davies, R Löbenberg

DISSOLUTION TECHNOLOGIES 29 (2), 86-93

In Vitro Evaluation of a Foamable Microemulsion Towards an Improved Topical Delivery of Diclofenac Sodium

B Hajjar, J Zuo, C Park, S Azarmi, DA Silva, NA Bou-Chacra, ...

AAPS PharmSciTech 23 (4), 102

2021

Improved bioavailability of poorly water-soluble drug by targeting increased absorption through solubility enhancement and precipitation inhibition

JH Lee, C Park, KY Weon, CY Kang, BJ Lee, JB Park

Pharmaceuticals 14 (12), 1255

Modulation of the clinically accessible gelation time using glucono-d-lactone and pyridoxal 5′-phosphate for long-acting alginate in situ forming gel injectable

H Kim, D Song, HV Ngo, G Jin, C Park, JB Park, BJ Lee

Carbohydrate Polymers 272, 118453

Evaluation of the impact of abuse deterring agents on the physicochemical factors of tramadol-loaded tablet and the definition of new abuse deterrent index

DG Won, G Park, HV Ngo, G Jin, C Park, BJ Lee

International Journal of Pharmaceutics 605, 120726

Development of a novel cannabinoid-loaded microemulsion towards an improved stability and transdermal delivery

C Park, J Zuo, V Somayaji, BJ Lee, R Löbenberg

International Journal of Pharmaceutics 604, 120766

Effect of pH adjustment and ratio of oppositely charged polymers on the mechanistic performance and sustained release of volatile perfume in interpolyelectrolyte complex …

J Lee, HV Ngo, G Jin, C Park, JB Park, PHL Tran, TTD Tran, VH Nguyen, ...

International Journal of Pharmaceutics 604, 120672

Role of surfactant micellization for enhanced dissolution of poorly water-soluble cilostazol using poloxamer 407-based solid dispersion via the anti-solvent method

G Jin, HV Ngo, JH Cui, J Wang, C Park, BJ Lee

Pharmaceutics 13 (5), 662

Double-controlled release of poorly water-soluble paliperidone palmitate from self-assembled albumin-oleic acid nanoparticles in PLGA in situ forming implant

Y Yu, HV Ngo, G Jin, PHL Tran, TTD Tran, VH Nguyen, C Park, BJ Lee

International Journal of Nanomedicine, 2819-2831

Traditional Chinese medicine “pill”, an ancient dosage form with surprising modern pharmaceutical characteristics

J Zuo, C Park, JYC Kung, NA Bou-Chacra, M Doschak, R Löbenberg

Pharmaceutical Research 38, 199-211

2020

Mechanistic understanding of salt-induced drug encapsulation in nanosuspension via acid-base neutralization as a nanonization platform technology to enhance dissolution rate of …

H Van Ngo, C Park, TTD Tran, BJ Lee

European Journal of Pharmaceutics and Biopharmaceutics 154, 8-17

Importance of the fatty acid chain length on in vitro and in vivo anticancer activity of fattigation-platform albumin nanoparticles in human colorectal cancer xenograft mice model

C Park, N Baek, R Loebenberg, BJ Lee

Journal of Controlled Release 324, 55-68

Fatty acid chain length impacts nanonizing capacity of albumin-fatty acid nanomicelles: Enhanced physicochemical property and cellular delivery of poorly water-soluble drug

C Park, N Meghani, R Loebenberg, JH Cui, QR Cao, BJ Lee

European Journal of Pharmaceutics and Biopharmaceutics 152, 257-269

Preparation and evaluation of identifiable quick response (QR)-coded orodispersible films using 3D printer with directly feeding nozzle

BC Oh, G Jin, C Park, JB Park, BJ Lee

International Journal of Pharmaceutics 584, 119405

Shear stress-dependent targeting efficiency using self-assembled gelatin–oleic nanoparticles in a biomimetic microfluidic system

T Kang, C Park, N Meghani, TTD Tran, PHL Tran, BJ Lee

Pharmaceutics 12 (6), 555

Combinatory interpretation of protein corona and shear stress for active cancer targeting of bioorthogonally clickable gelatin-oleic nanoparticles

NM Meghani, H Amin, C Park, JH Cui, QR Cao, KH Choi, BJ Lee

Materials Science and Engineering: C 111, 110760

Utilization of a fattigation platform gelatin-oleic acid sodium salt conjugate as a novel solubilizing adjuvant for poorly water-soluble drugs via self-assembly and nanonization

D Kim, C Park, NM Meghani, TTD Tran, PHL Tran, JB Park, BJ Lee

International journal of pharmaceutics 575, 118892

2019

The roles of short and long chain fatty acids on physicochemical properties and improved cancer targeting of albumin-based fattigation-platform nanoparticles containing doxorubicin

C Park, N Meghani, H Amin, PHL Tran, TTD Tran, VH Nguyen, BJ Lee

International journal of pharmaceutics 564, 124-135

Double controlled release of highly insoluble cilostazol using surfactant-driven pH dependent and pH-independent polymeric blends and in vivo bioavailability in beagle dogs

KY Nam, SM Cho, YW Choi, C Park, NM Meghani, JB Park, BJ Lee

International Journal of Pharmaceutics 558, 284-290

Investigation of crystallization and salt formation of poorly water-soluble telmisartan for enhanced solubility

C Park, NM Meghani, Y Shin, E Oh, JB Park, JH Cui, QR Cao, TTD Tran, ...

Pharmaceutics 11 (3), 102

2018

Modulation of serum albumin protein corona for exploring cellular behaviors of fattigation-platform nanoparticles

NM Meghani, HH Amin, TTD Tran, PHL Tran, C Park, BJ Lee

Colloids and Surfaces B: Biointerfaces 170, 179-186

pH-independent controlled release tablets containing nanonizing valsartan solid dispersions for less variable bioavailability in humans

JB Park, C Park, ZZ Piao, HH Amin, NM Meghani, PHL Tran, TTD Tran, ...

Journal of Drug Delivery Science and Technology 46, 365-377

Design and evaluation of clickable gelatin-oleic nanoparticles using fattigation-platform for cancer therapy

NM Meghani, HH Amin, C Park, JB Park, JH Cui, QR Cao, BJ Lee

International Journal of Pharmaceutics 545 (1-2), 101-112

New blends of hydroxypropylmethylcellulose and Gelucire 44/14: physical property and controlled release of drugs with different solubility

KH Lee, C Park, G Oh, JB Park, BJ Lee

Journal of Pharmaceutical Investigation 48, 313-321

Reprecipitation of poorly water-soluble cilostazol crystals using adsorbing carriers for enhanced dissolution and physicochemical modification

N Baek, GH Oh, C Park, TTT Tran, YJ Park, E Oh, H Le, TTD Tran, JB Park, ...

Journal of drug delivery science and technology 43, 477-486

2017

Fattigation-platform nanoparticles using apo-transferrin stearic acid as a core for receptor-oriented cancer targeting

HH Amin, NM Meghani, C Park, TTD Tran, PHL Tran, BJ Lee

Colloids and Surfaces B: Biointerfaces 159, 571-579

Patient-centered drug delivery and its potential applications for unmet medical needs

C Park, NM Meghani, HH Amin, VH Nguyen, BJ Lee

Therapeutic delivery 8 (9), 775-790

Design of fixed dose combination and physicochemical characterization of enteric-coated bilayer tablet with circadian rhythmic variations containing telmisartan and pravastatin …

D Luo, JH Kim, C Park, E Oh, JB Park, JH Cui, QR Cao, BJ Lee

International Journal of Pharmaceutics 523 (1), 343-356

Modulation of microenvironmental pH for dual release and reduced in vivo gastrointestinal bleeding of aceclofenac using hydroxypropyl methylcellulose-based …

WH Kang, H Van Nguyen, C Park, YW Choi, BJ Lee

European Journal of Pharmaceutical Sciences 102, 85-93

Biomimetic shear stress and nanoparticulate drug delivery

T Kang, TTT Tran, C Park, BJ Lee

Journal of Pharmaceutical Investigation 47, 133-139

2016

Investigation of biomimetic shear stress on cellular uptake and mechanism of polystyrene nanoparticles in various cancer cell lines

T Kang, C Park, BJ Lee

Archives of pharmacal research 39, 1663-1670

Improving the dissolution rate of a poorly water-soluble drug via adsorption onto pharmaceutical diluents

H Van Nguyen, C Park, E Oh, BJ Lee

Journal of Drug Delivery Science and Technology 35, 146-154

Effect of biomimetic shear stress on intracellular uptake and cell-killing efficiency of doxorubicin in a free and liposomal formulation

T Kang, Y Cho, C Park, SD Kim, E Oh, JH Cui, QR Cao, BJ Lee

International journal of pharmaceutics 510 (1), 42-47

Effects of shear stress on the cellular distribution of polystyrene nanoparticles in a biomimetic microfluidic system

T Kang, C Park, JS Choi, JH Cui, BJ Lee

Journal of Drug Delivery Science and Technology 31, 130-136

2015

Micromeritic properties and instrumental analysis of physical mixtures and solid dispersions with adsorbent containing losartan: Comparison of dissolution-differentiating factors

TH Tran, C Park, T Kang, YJ Park, E Oh, BJ Lee

Powder Technology 272, 269-275

New method and characterization of self-assembled gelatin–oleic nanoparticles using a desolvation method via carbodiimide/N-hydroxysuccinimide (EDC/NHS) reaction

C Park, CLN Vo, T Kang, E Oh, BJ Lee

European Journal of Pharmaceutics and Biopharmaceutics 89, 365-373

2013

Current trends and future perspectives of solid dispersions containing poorly water-soluble drugs

CLN Vo, C Park, BJ Lee

European journal of pharmaceutics and biopharmaceutics 85 (3), 799-813

Development of Fixed-Dose Combination with Dual-Release Properties Using Double-Melt Extrusion Technology

HK Seo, C Park, IH Park, CY Kang, BJ Lee, I de la Peña, KY Weon, ...

Available at SSRN 4446912