公開論文（最新のものから）

Ando M, Yamaguchi H, Iwashita N, Takagi Y, Yoshinari T, Fukuyama T (corresponding author). Oral Exposure to Low Concentration of Fumonisin B2, but Not Fumonisin B1, Significantly Exacerbates the Pathophysiology of Imiquimod-Induced Psoriasis in Mice. Int J Mol Sci. 2024 Jul 18;25(14):7852. doi: 10.3390/ijms25147852. PMID: 39063102 

Shirahata S, Katayama Y, Kaneki M, Uchiyama J, Fukuyama T (corresponding author). The Effect of Subacute Oral Folic Acid Treatment on Growth of Porphyromonas gulae in Dogs. J Vet Dent. 2024 Jul;41(4):281-287. doi: 10.1177/08987564231189650. Epub 2023 Jul 27. PMID: 37499183

Matsuzaka R, Yamaguchi H, Ohira C, Kurita T, Iwashita N, Takagi Y, Nishino T, Noda K, Sugita K, Kushiro M, Miyake S, Fukuyama T (corresponding author). Sub-acute oral exposure to lowest observed adverse effect level of nivalenol exacerbates atopic dermatitis in mice via direct activation of mitogen-activated protein kinase signal in antigen-presenting cells. Arch Toxicol. 2024 Jul;98(7):2173-2183. doi: 10.1007/s00204-024-03740-3. Epub 2024 Apr 14. PMID: 38616237 

Yasuda J, Yasuda H, Nomura R, Matayoshi S, Inaba H, Gongora E, Iwashita N, Shirahata S, Kaji N, Akitomo T, Mitsuhata C, Uchiyama J, Fukuyama T, Matsumoto-Nakano M, Nakano K, Murakami M. Investigation of periodontal disease development and Porphyromonas gulae FimA genotype distribution in small dogs. Sci Rep. 2024 Mar 4;14(1):5360. doi: 10.1038/s41598-024-55842-8. PMID: 38438471 

Ohira C, Tomita K, Kaneki M, Iwashita N, Takagi Y, Kurihara T, Nagane M, Kamiie J, Fukuyama T (corresponding author). Effects of low concentrations of ozone gas exposure on percutaneous oxygen saturation and inflammatory responses in a mouse model of Dermatophagoides farinae-induced asthma. Arch Toxicol. 2023 Dec;97(12):3151-3162. doi: 10.1007/s00204-023-03593-2. Epub 2023 Sep 21. PMID: 37733069  

Kaneki M, Ohira C, Takahashi M, Iwashita N, Takagi Y, Nagane M, Uchiyama J, Fukuyama T (corresponding author). Therapeutic potential of ozone water treatment in alleviating atopic dermatitis symptoms in mouse models: Exploring its bactericidal and direct anti-inflammatory properties. Int Immunopharmacol. 2023 Nov;124(Pt A):110920. doi: 10.1016/j.intimp.2023.110920. Epub 2023 Sep 14. PMID: 37716162 

Ando M, Yamaguchi H, Morimoto A, Iwashita N, Takagi Y, Nagane M, Yoshinari T, Fukuyama T (corresponding author). Chronic oral exposure to low-concentration fumonisin B2 significantly exacerbates the inflammatory responses of allergies in mice via inhibition of IL-10 release by regulatory T cells in gut-associated lymphoid tissue. Arch Toxicol. 2023 Oct;97(10):2707-2719. doi: 10.1007/s00204-023-03579-0. Epub 2023 Aug 17. PMID: 37589943 

Komuro M, Mizugaki H, Nagane M, Morimoto M, Fukuyama T, Ogihara K, Naya Y, Yokomori E, Kaneshima K, Kawakami Y, Kamiie J, Shibata Y, Suzuki M, Shimizu T, Kawashima N, Okamoto M, Ikeda T, Yamashita T. Ganglioside GM3 deficiency enhances mast cell sensitivity. FEBS J. 2023 Sep;290(17):4268-4280. doi: 10.1111/febs.16806. Epub 2023 May 5. PMID: 37098812 

Yamaguchi H, Ando M, Iwashita N, Takagi Y, Kushiro M, Fukuyama T (corresponding author). Oral exposure to citrinin significantly exacerbates the pathophysiology of a mouse model of imiquimod-induced psoriasis via direct activation of dendritic cell. J Appl Toxicol. 2023 Sep;43(9):1284-1292. doi: 10.1002/jat.4462. Epub 2023 Mar 20. PMID: 36908085

Shirahata S, Iwashita N, Sasaki R, Nomura R, Murakami M, Yasuda J, Yasuda H, Nakajima K, Inaba H, Matsumoto-Nakano M, Nakano K, Uchiyama J, Fukuyama T (corresponding author). Possible association of fimA genotype of Porphyromonas gulae with the severity of periodontal disease and the number of permanent teeth in dogs. Front Vet Sci. 2023 Feb 6;10:1022838. doi: 10.3389/fvets.2023.1022838. eCollection 2023. PMID: 36814464 

Suzuki R, Mishima M, Nagane M, Mizugaki H, Suzuki T, Komuro M, Shimizu T, Fukuyama T, Takeda S, Ogata M, Miyamoto T, Aihara N, Kamiie J, Kamisuki S, Yokaryo H, Yamashita T, Satoh T. The novel sustained 3-hydroxybutyrate donor poly-D-3-hydroxybutyric acid prevents inflammatory bowel disease through upregulation of regulatory T-cells. FASEB J. 2023 Jan;37(1):e22708. doi: 10.1096/fj.202200919R. PMID: 36562544

Uchiyama J, Takemura-Uchiyama I, Gotoh K, Kato SI, Sakaguchi Y, Murakami H, Fukuyama T, Kaneki M, Matsushita O, Matsuzaki S. Phylogenic analysis of new viral cluster of large phages with unusual DNA genomes containing uracil in place of thymine in gene-sharing network, using phages S6 and PBS1 and relevant uncultured phages derived from sewage metagenomics. Virus Res. 2022 Oct 2;319:198881. doi: 10.1016/j.virusres.2022.198881. Epub 2022 Aug 4. PMID: 35934259  

Komuro M, Nagane M, Fukuyama T, Luo X, Hiraki S, Miyanabe M, Ishikawa M, Niwa C, Murakami H, Okamoto M, Yamashita T. Sphingomyelin maintains the cutaneous barrier via regulation of the STAT3 pathway. FASEB J. 2022 Apr;36(4):e22111. doi: 10.1096/fj.202100721RR. PMID: 35230716 

Takemura-Uchiyama I, Tsurui H, Shimakura H, Nasukawa T, Imanishi I, Uchiyama J, Fukuyama T, Sakamoto S, Morisawa K, Fujimura M, Murakami H, Kanamaru S, Kurokawa K, Kawamoto K, Iyori K, Sakaguchi M. Heterogeneous IgE reactivities to Staphylococcus pseudintermedius strains in dogs with atopic dermatitis, and the identification of DM13-domain-containing protein as a bacterial IgE-reactive molecule. FEMS Microbiol Lett. 2022 Feb 26;369(1):fnac019. doi: 10.1093/femsle/fnac019. PMID: 35191469

Komuro M, Nagane M, Endo R, Nakamura T, Miyamoto T, Niwa C, Fukuyama T, Harashima H, Aihara N, Kamiie J, Suzuki R, Yamashita T. Glucosylceramide in T cells regulates the pathology of inflammatory bowel disease. Biochem Biophys Res Commun. 2022 Apr 9;599:24-30. doi: 10.1016/j.bbrc.2022.02.004. Epub 2022 Feb 3. PMID: 35168060

Tomita K, Okawara T, Ohira C, Morimoto A, Aihara R, Kurihara T, Fukuyama T (corresponding author). An Acceptable Concentration (0.1 ppm) of Ozone Exposure Exacerbates Lung Injury in a Mouse Model. Am J Respir Cell Mol Biol. 2021 Dec;65(6):674-676. doi: 10.1165/rcmb.2021-0302LE. PMID: 34554898   

Kishimoto R, Kato N, Koike M, Iwashita N, Takagi Y, Fukuyama T (corresponding author). Topical treatment with mastic (resin from Pistacia lentiscus) elicits anti-inflammatory and anti-pruritic responses by modulating keratinocyte activation in a mouse model of allergic dermatitis. Phytomedicine. 2021 Oct;91:153679. doi: 10.1016/j.phymed.2021.153679. Epub 2021 Jul 19. PMID: 34332283

Ookawara T, Aihara R, Morimoto A, Iwashita N, Kurata K, Takagi Y, Miyasaka A, Kushiro M, Miyake S, Fukuyama T (corresponding author). Acute and Subacute Oral Toxicity of Deoxynivalenol Exposure in a Dermatophagoides farinae-Induced Murine Asthma Model. Toxicol Sci. 2021 Jan 28;179(2):229-240. doi: 10.1093/toxsci/kfaa168. PMID: 33170220

Aihara R, Ookawara T, Morimoto A, Iwashita N, Takagi Y, Miyasaka A, Kushiro M, Miyake S, Fukuyama T (corresponding author). Acute and subacute oral administration of mycotoxin deoxynivalenol exacerbates the pro-inflammatory and pro-pruritic responses in a mouse model of allergic dermatitis. Arch Toxicol. 2020 Dec;94(12):4197-4207. doi: 10.1007/s00204-020-02875-3. Epub 2020 Aug 19. PMID: 32813090   

Tajima H, Tajiki-Nishino R, Watanabe Y, Kurata K, Fukuyama T (corresponding author). Activation of aryl hydrocarbon receptor by benzo[a]pyrene increases interleukin 33 expression and eosinophil infiltration in a mouse model of allergic airway inflammation. J Appl Toxicol. 2020 Nov;40(11):1545-1553. doi: 10.1002/jat.4017. Epub 2020 Jun 18. PMID: 32557721

Iwano R, Iwashita N, Takagi Y, Fukuyama T (corresponding author). Estrogen receptor α activation aggravates imiquimod-induced psoriasis-like dermatitis in mice by enhancing dendritic cell interleukin-23 secretion. J Appl Toxicol. 2020 Oct;40(10):1353-1361. doi: 10.1002/jat.3988. Epub 2020 May 5. PMID: 32368827

Ishimota M, Tajiki-Nishino R, Fukuyama T, Tomiyama N. Rapid adaptation of Chironomus yoshimatsui to acetylcholinesterase inhibitors (pyraclofos and pirimicarb) in a multi-generation study. J Environ Sci Health B. 2020;55(5):429-437. doi: 10.1080/03601234.2019.1708165. Epub 2020 Feb 17. PMID: 32065017

Ganchingco JRC, Fukuyama T, Yoder JA, Bäumer W. Calcium imaging of primary canine sensory neurons: Small-diameter neurons responsive to pruritogens and algogens. Brain Behav. 2019 Dec;9(12):e01428. doi: 10.1002/brb3.1428. Epub 2019 Sep 30. PMID: 31571393    

Makino E, Fukuyama T (corresponding author), Watanabe Y, Tajiki-Nishino R, Tajima H, Ohnuma-Koyama A, Takahashi N, Ohtsuka R, Okazaki Y. Subacute oral administration of folic acid elicits anti-inflammatory response in a mouse model of allergic dermatitis. J Nutr Biochem. 2019 May;67:14-19. doi: 10.1016/j.jnutbio.2019.01.009. Epub 2019 Jan 26. PMID: 30831459

Tajiki-Nishino R, Watanabe Y, Fukuyama T (corresponding author). Effect of prenatal exposure to combined immunosuppressive agrochemicals in a mouse model of allergic airway inflammation. J Vet Med Sci. 2019 Apr 16;81(4):541-544. doi: 10.1292/jvms.18-0641. Epub 2019 Feb 15. PMID: 30773519

Tajima H, Tajiki-Nishino R, Watanabe Y, Fukuyama T (corresponding author). Direct activation of aryl hydrocarbon receptor by benzo[a]pyrene elicits T-helper 2-driven proinflammatory responses in a mouse model of allergic dermatitis. J Appl Toxicol. 2019 Jul;39(7):936-944. doi: 10.1002/jat.3782. Epub 2019 Feb 12. PMID: 30748024

Watanabe Y, Tajiki-Nishino R, Tajima H, Fukuyama T (corresponding author). Role of estrogen receptors α and β in the development of allergic airway inflammation in mice: A possible involvement of interleukin 33 and eosinophils. Toxicology. 2019 Jan 1;411:93-100. doi: 10.1016/j.tox.2018.11.002. Epub 2018 Nov 13. PMID: 30445053