I am a fourth-year Ph.D. Candidate in the lab of Dr. Evan Worden (Worden Laboratory), Department of Structural Biology at Van Andel Institute, Michigan, USA. Currently, I am developing a novel in vitro biochemical tool to study the histone modifications crosstalk mediated by chromatin-modifying complexes that regulate gene transcription, underpinning cancer development. I will employ biochemical assays and state-of-the-art Cryo-Electron Microscopy (Cryo-EM) to validate the effectiveness of this tool and unravel the underlying crosstalk mechanism associated with it.
Before joining Van Andel Institute Graduate School, I earned my Bachelor of Technology (B.Tech) in Biotechnology from Adamas University in Kolkata, West Bengal, India. During my bachelor’s degree, I was an undergraduate student researcher in Dr. Kuntal Pal's lab, where I worked on several computer-aided drug design projects. These projects involved exploring the pharmacological roles of small-molecule inhibitors and phytochemicals targeting human GPCRs and viral proteins of SARS-CoV-2, Nipah Virus, Dengue Virus, and Marburg Virus, using high-throughput virtual screening, homology modeling, molecular docking, and molecular dynamics simulation. Some of my undergraduate work has been published in peer-reviewed international journals. During this lab experience, I became intrigued to pursue a Ph.D. focused on Structural Biology.
My overall expertise includes protein biochemistry, cancer epigenetics, computer-aided drug design, de novo protein and ligand design, histone modifications, immunoinformatics, structural bioinformatics, and structural biology (cryo-EM).
Outside of my research and academics, I enjoy cooking, traveling, photography, and illustrations. I also love spending time with myself and my family.