Software for estimation of the inbreeding coefficient of individuals through use of a dense map of genetic markers and computation of genomically controlled homozygosity mapping lodscores.
If you use FEstim, please cite the following references:
- For homozygosity mapping: Leutenegger Al, Labalme A, Genin E, Toutain A, Steichen E, Clerget-Darpoux F, Edery P (2006) Using genomic inbreeding coefficient estimates for homozygosity mapping of rare recessive traits; Application to the Taybi-Linder syndrome. Am J Hum Genet. 79:62-6
- For inbreeding coefficient estimation: Leutenegger AL, Prum B, Genin E, Verny C, Lemainque A, Clerget-Darpoux F, Thompson EA. (2003) Estimation of the inbreeding coefficient through use of genomic data. Am J Hum Genet. 73:516-23
==Downloading FEstim==
FEstim version 1.3.2 is freely available under GNU GPL license.
==Contact us==
Contact us if you have any problems or suggestions with the software.