Andresen Nature Center's indoor hive has provided guests with an up close look at the internal operations of a real working honeybee colony. Throughout the year, you can observe the queen laying eggs, the pollen harvest and the drone's demise.
This is an excellent overview on what the experts think is happening to the honey bee colony die-offs: It isn't one issue but a combination of four or more factors, as discussed in the video. I've read a few articles that argue that neonics are probably not a major issue for our bees, as the concentration level in the pollen and nectar is pretty low. Diseases - typically brought in by mites - are usually identified to be the primary cause of a colony die-off, but the fact that the diseases cannot be overcome by the bee colony - due to other factors - needs to be taken into consideration. The speaker's main point is not to eliminate insecticides and herbicides (we cannot afford to do that anyway, as the 8 billion humans on this earth would probably go to war over the reduced food availability), but to give bees alternative food sources that are healthy for them, and not contaminated. Plant some pollinators!