Ortega‐Villa AM, Grieco MC, Rubenstein K, Wang J, Proschan MA. Futility Monitoring in Clinical Trials. Statistics in Medicine. 2025 Jun;44(13-14):e70157.
Manthiram K, Ortega-Villa AM, Lapidus S, Bowes M, Romeo T, Garguilo K, Failla L, Srinivasalu H, Mudd P, Ombrello A, Barron K. Features Associated with Response to Tonsillectomy in Periodic Fever, Aphthous Stomatitis, Pharyngitis, and Cervical Adenitis Syndrome in Children. The Journal of Pediatrics. 2025 Mar 21:114559.
Ortega-Villa AM, Nason MC, Fay MP, Follmann DA. Regression approaches to assess effect of treatments that arrest progression of symptoms. Statistics in Medicine. 2024.
Casazza JP, Hofstetter AR, Costner PJM, Holman LA, Hendel CS, Widge AT, Wu RL, Whalen WR, Cunningham J, Arthur A, Wang X, Ola A, Saunders J, Mendoza F, Novik L, Burgos Florez MC, Ortega-Villa AM, Apte PJ, Strom L, Dropulic LK, The VRC 323 study team. Phase 1 dose-escalation trial evaluating a group 2 influenza hemagglutinin stabilized stem nanoparticle vaccine. npj Vaccines. 2024;9:171.
Galindo-Fraga A, del Carmen Guerra-de-Blas P, Ortiz-Hernández AA, Rubenstein K, Ortega-Villa AM, Ramírez-Venegas A, Valdez-Vázquez R, Moreno-Espinosa S, Llamosas-Gallardo B, Pérez-Patrigeon S, Noyola DE. Prospective cohort study of patient demographics, viral agents, seasonality, and outcomes of influenza-like illness in Mexico in the late H1N1-pandemic and post-pandemic years (2010-2014). IJID regions. 2024 Sep 1;12:100394.
Gonzales-Wartz KK, Sá JM, Lee K, Gebremicale Y, Deng B, Long CA, Pascini TV, Laughinghouse A, Moretz SE, Ortega-Villa AM, Fay MP. Infectivity of Plasmodium parasites to Aedes aegypti and Anopheles stephensi mosquitoes maintained on blood-free meals of SkitoSnack. Parasites & Vectors. 2024 Jul 6;17(1):290.
Rocco JM, Zhou Y, Liu NS, Laidlaw E, Galindo F, Anderson MV, Rupert A, Lage SL, Ortega-Villa AM, Yu S, Lisco A. Clonal hematopoiesis in people with advanced HIV and associated inflammatory syndromes. JCI insight. 2024 May 5;9(9).
Gedik KC, Ortega-Villa AM, Materne G, Rastegar A, Sanchez GA, Reinhardt A, Brogan PA, Berkun Y, Murias S, Robles M, Schalm S. Disease flares with baricitinib dose reductions and development of flare criteria in patients with CANDLE/PRAAS. Annals of the rheumatic diseases. 2024 Apr 23.
Sherman AC, Tuan J, Cantos VD, Adeyiga O, Mahoney S, Ortega-Villa AM, Tillman A, Whitaker J, Woodward Davis AS, Leav B, Hirsch I, Sadoff J, Dunkle LM, Gilbert PB, Janes HJ, Kublin JG, Goepfert PA, Kotloff K, Rouphael N, Falsey AR, El Sahly HM, Sobieszczyk ME, Huang Y, Neuzil KM, Corey L, Grinsztejn B, Gray G, Nasion MC, Baden LR, Gay CL. Coronavirus Disease 2019 Vaccine Efficacy in Participants With Weakened Immune Systems From 4 Randomized controlled Trials. Clinical Infectious Diseases. 2024 Apr 10:ciae192.
Proschan MA, Nason M, Ortega-Villa AM, Wang J. Changing interim monitoring in response to internal clinical trial data. Biometrics. 2024 Mar;80(1):ujae006.
Gamiño-Arroyo AE, Arellano-Galindo J, Guerra-de-Blas PD, Ortega-Villa AM, Mateja A, Llamosas-Gallardo B, Ortíz-Hernández AA, Valdéz-Vázquez R, Ramírez-Venegas A, Galindo-Fraga A, Guerrero ML. Clinical and molecular characterization of children and adults with respiratory bocavirus infection in Mexico: a cross-sectional nested study within the ILI002 prospective observational study. The Lancet Regional Health–Americas. 2024 Jan 1;29.
Mwesigwa B, Houser KV, Hofstetter AR, Ortega-Villa AM, Naluyima P, Kiweewa F, Nakabuye I, Yamshchikov GV, Andrews C, O'Callahan M, Strom L. Safety, tolerability, and immunogenicity of the Ebola Sudan chimpanzee adenovirus vector vaccine (cAd3-EBO S) in healthy Ugandan adults: a phase 1, open-label, dose-escalation clinical trial. The Lancet Infectious Diseases. 2023 Dec 1;23(12):1408-17.
Zendt M, Bustos Carrillo FA, Kelly S, Saturday T, DeGrange M, Ginigeme A, Wu L, Callier V, Ortega-Villa AM, Faust M, Chang-Rabley E. Characterization of the antispike IgG immune response to COVID-19 vaccines in people with a wide variety of immunodeficiencies. Science Advances. 2023 Oct 12;9(41):eadh3150.
Lisco A, Ortega-Villa AM, Sereti I. Idiopathic CD4 Lymphocytopenia at 30 Years. Reply. The New England journal of medicine. 2023 Aug 17;389(7):675-6.
Ortega-Villa AM, Hynes NA, Levine CB, Yang K, Wiley Z, Jilg N, Wang J, Whitaker JA, Colombo CJ, Nayak SU, Kim HJ. Evaluating demographic representation in clinical trials: use of the Adaptive Coronavirus Disease 2019 Treatment Trial (ACTT) as a test case. InOpen forum infectious diseases 2023 Jun (Vol. 10, No. 6, p. ofad290). US: Oxford University Press.
Lisco A, Ortega-Villa AM, Mystakelis H, Anderson MV, Mateja A, Laidlaw E, Manion M, Roby G, Higgins J, Kuriakose S, Walkiewicz MA. Reappraisal of idiopathic CD4 lymphocytopenia at 30 years. New England Journal of Medicine. 2023 May 4;388(18):1680-91.
Byrd DA, Vogtmann E, Ortega-Villa AM, Wan Y, Gomez M, Hogue S, Warner A, Zhu B, Dagnall C, Jones K, Hicks B. Prospective and cross-sectional associations of the rectal tissue microbiome with colorectal adenoma recurrence. Cancer Epidemiology, Biomarkers & Prevention. 2023 Mar 6;32(3):435-43.
del Carmen Guerra-de-Blas P, Ortega-Villa AM, Ortiz-Hernández AA, Ramírez-Venegas A, Moreno-Espinosa S, Llamosas-Gallardo B, Pérez-Patrigeon S, Hunsberger S, Magaña M, Valdez-Vázquez R, Freimanis L. Etiology, clinical characteristics, and risk factors associated with severe influenza-like illnesses in Mexican adults. IJID regions. 2023 Mar 1;6:152-8.
Manion M, Boulougoura A, Naqvi N, Lage SL, Richards E, Grivas C, Laidlaw E, Kuriakose S, Ortega-Villa AM, Tadros S, Roby G. Polyfunctional Antigen Specific CD4+ T cell Responses in Patients With Human Immunodeficiency Virus/AIDS and Histoplasmosis Immune Reconstitution Inflammatory Syndrome. Clinical Infectious Diseases. 2023 Feb 1;76(3):531-4.
Rocco JM, Laidlaw E, Galindo F, Anderson M, Rupert A, Higgins J, Sortino O, Ortega-Villa AM, Sheikh V, Roby G, Kuriakose S. Severe mycobacterial immune reconstitution inflammatory syndrome (IRIS) in advanced human immunodeficiency virus (HIV) has features of hemophagocytic lymphohistiocytosis and requires prolonged immune suppression. Clinical Infectious Diseases. 2023 Feb 1;76(3):e561-70.
Hamer MJ, Houser KV, Hofstetter AR, Ortega-Villa AM, Lee C, Preston A, Augustine B, Andrews C, Yamshchikov GV, Hickman S, Schech S. Safety, tolerability, and immunogenicity of the chimpanzee adenovirus type 3-vectored Marburg virus (cAd3-Marburg) vaccine in healthy adults in the USA: a first-in-human, phase 1, open-label, dose-escalation trial. The Lancet. 2023 Jan 28;401(10373):294-302.
Hamrah SD, Gallagher S, Ortega-Villa AM, Wheatley LM, Touré O. Impact of extramural DAIT/NIAID pharmacy programs, research pharmacist scientist oversight on study performance, and lessons learned. Contemporary clinical trials. 2023 Jan 1;124:106938.
Grantz KL, Ortega-Villa AM, Pugh SJ, Bever A, Grobman W, Newman RB, Owen J, Wing DA, Albert PS. Combination of fundal height and ultrasound to predict small for gestational age at birth. American journal of perinatology. 2023 Jan;40(02):155-62.
Lau CY, Adan MA, Earhart J, Seamon C, Nguyen T, Savramis A, Adams L, Zipparo ME, Madeen E, Huik K, Grossman Z, Chimukangara B, Wulan WN, Millo C, Nath A, Smith BR, Ortega-Villa AM, Proschan M, Wood BJ, Hammoud D, Maldarelli F. Imaging and biopsy of HIV-infected individuals undergoing analytic treatment interruption. Frontiers in Medicine. 2022 Aug 22;9:979756.
Galindo-Fraga A, Guerra-de-Blas PD, Ortega-Villa AM, Mateja A, Ruiz Quiñones JA, Ramos Cervantes P, Ledesma Barrientos F, Ortiz-Hernández AA, Llamosas-Gallardo B, Ramírez-Venegas A, Valdéz Vázquez R. Different clinical presentations of human rhinovirus species infection in children and adults in Mexico. InOpen Forum Infectious Diseases 2022 Jul 1 (Vol. 9, No. 7, p. ofac303). Oxford University Press.
Marques A, Okpali G, Liepshutz K, Ortega‐Villa AM. Characteristics and outcome of facial nerve palsy from Lyme neuroborreliosis in the United States. Annals of Clinical and Translational Neurology. 2022 Jan;9(1):41-9.
Makovoz A, Wang J, Oshegbo G, Park YH, Lyons JJ, Eisch AR, Scott LM, Reynolds JC, Ortega-Villa AM, Metcalfe DD, Komarow HD. Assessment of osteoporosis and fracture risk in mastocytosis within a North American cohort. The Journal of Allergy and Clinical Immunology: In Practice. 2021 Dec 1;9(12):4459-67.
Ruckwardt TJ, Morabito KM, Phung E, Crank MC, Costner PJ, Holman LA, Chang LA, Hickman SP, Berkowitz NM, Gordon IJ, Yamshchikov GV, Gaudinski MR, Lin B, Bailer R, Chen M, Ortega-Villa AM, Nguyen T, Kumar A, Schwartsz RM, Kueltzo LA, Stein JA, Carlton K, Hall JG, Nason MC, Mascola JR, Chen G, Graham BS, VRC 317 Study Team . Safety, tolerability, and immunogenicity of the respiratory syncytial virus prefusion F subunit vaccine DS-Cav1: a phase 1, randomised, open-label, dose-escalation clinical trial. The Lancet Respiratory Medicine. 2021 Oct 1;9(10):1111-20.
Ortega‐Villa AM, Nason MC, Follmann D. The mechanistic analysis of founder virus data in challenge models. Statistics in Medicine. 2021 Sep 10;40(20):4492-504.
Rocco JM, Laghetti P, Di Stefano M, Sereti I, Ortega-Villa AM, Wang J, Rupert A, Chironna M, Ye P, Liu X, Anderson MV. Impact of innate immunity, endothelial damage, and metabolic biomarkers on COVID-19 severity and mortality. InOpen forum infectious diseases 2022 Sep 1 (Vol. 9, No. 9, p. ofac427). Oxford University Press.
Belaunzaran-Zamudio PF, Ortega-Villa AM, Mimenza-Alvarado AJ, Guerra-De-Blas PD, Aguilar-Navarro SG, Sepulveda-Delgado J, Hunsberger S, Salgado RV, Ramos-Castañeda J, Rincon Leon HA, Rodriguez de La Rosa P. Comparison of the impact of zika and dengue virus infection, and other acute illnesses of unidentified origin on cognitive functions in a prospective cohort in Chiapas Mexico. Frontiers in Neurology. 2021 Mar 22;12:631801.
Ortega-Villa AM, Kim I. Flexible derivative time-varying model in matched case-crossover studies for a small number of geographical locations among the participants. Statistical Methods in Medical Research. 2021 Feb;30(2):563-79.
Ortega-Villa AM, Liu D, Ward MH, Albert PS. New insights into modeling exposure measurements below the limit of detection. Environmental Epidemiology. 2021 Feb 1;5(1):e116.
Hunsberger S, Ortega-Villa AM, Powers III JH, León HA, Sosa SC, Hernández ER, Cancino JG, Nason M, Lumbard K, Sepulveda J, de Blas PD. Patterns of signs, symptoms, and laboratory values associated with Zika, dengue, and undefined acute illnesses in a dengue endemic region: Secondary analysis of a prospective cohort study in southern Mexico. International Journal of Infectious Diseases. 2020 Sep 1;98:241-9.
Hong GH, Ortega-Villa AM, Hunsberger S, Chetchotisakd P, Anunnatsiri S, Mootsikapun P, Rosen LB, Zerbe CS, Holland SM. Natural history and evolution of anti-interferon-γ autoantibody-associated immunodeficiency syndrome in Thailand and the United States. Clinical Infectious Diseases. 2020 Jun 24;71(1):53-62.
Pugh SJ, Ortega-Villa AM, Grobman W, Hinkle SN, Newman RB, Hediger M, Grewal J, Wing DA, Albert PS, Grantz KL. Longitudinal changes in maternal anthropometry in relation to neonatal anthropometry. Public health nutrition. 2019 Apr;22(5):797-804.
Ortega‐Villa AM, Albert PS. Estimating onset time from longitudinal data in the presence of measurement error with application to estimating gestational age from maternal anthropometry during pregnancy. Statistics in medicine. 2018 Dec 30;37(30):4743-57.
Pugh SJ, Ortega‐Villa AM, Grobman W, Newman RB, Owen J, Wing DA, Albert PS, Grantz KL. Estimating gestational age at birth from fundal height and additional anthropometrics: a prospective cohort study. BJOG: An International Journal of Obstetrics & Gynaecology. 2018 Oct;125(11):1397-404.
Ortega-Villa AM, Grantz KL, Albert PS. Estimating onset time from longitudinal and cross-sectional data with an application to estimating gestational age from longitudinal maternal anthropometry during pregnancy and neonatal anthropometry at birth. Journal of the Royal Statistical Society Series A: Statistics in Society. 2018 Jun;181(3):825-42.
Wing DA, Ortega-Villa AM, Grobman WA, Hediger ML, Grewal J, Pugh SJ, Kim S, Newman R, Chien E, Owen J, D’Alton ME. Maternal stress and neonatal anthropometry: the NICHD Fetal Growth Studies. American journal of obstetrics and gynecology. 2017 Jul 1;217(1):82-e1.
Ortega‐Villa AM, Kim I, Kim H. Semiparametric time varying coefficient model for matched case‐crossover studies. Statistics in Medicine. 2017 Mar 15;36(6):998-1013.