I am a computational biologist and biomedical engineer currently advising the Horizon Europe SMASH-HCM project on in silico modeling of hiPSC-derived cardiomyocytes and vascular smooth muscle cells. I develop multiscale mechanistic and data-driven models of the heart and vasculature that link molecular, cellular, and organ-level dynamics to clinical phenotypes. I enjoy applying novel statistical algorithms to omics data to uncover pathway-level remodeling in disease. I also build neural-network surrogates, including transformers and time-series architectures, for fast emulation, robust parameter inference, and uncertainty quantification in biophysical systems.

Outside academia, I enjoy spending time with my family, gaming, reading, and collecting fountain pens.

Training / Fellowship

Postdoc (Sep 2024 - May 2026) University of California Davis, USA
Quantitative Pharmacology

Postdoc (Apr 2024 - Sep 2024) Tampere University, Finland
Biomedical Engineering

Education

DSc (2019-2024) Tampere University, Finland
Biomedical Engineering, graduated with distinction
Thesis: Mathematical Modeling of Cardiomyocytes Pathophysiology and Biomechanics
Supervisor: Dr. Jari Hyttinen

MS (2014-2017) Sharif University of Technology, Iran
Mechanical Engineering (Applied Design-Biomechanics)
GPA: 3.91/4.
Thesis: Numerical Study of Margination and Adhesion of Micro- and Nanoparticles in Coronary Circulation
Supervisor: Dr. Amir Shamloo

BS (2009-2014) Isfahan University of Technology, Iran
Mechanical Engineering
Thesis: Design, Damage Analysis, and Manufacturing Strategies for CNG Type III Pressure Vessels                                 Using Finite Element Method.
Supervisor: Dr. Reza Jafari Nedoushan

A compact, reproducible ML pipeline for predicting protein variant effects from sequence:

protein-variant-effect

Mathematical models of human induced pluripotent stem cell-derived cardiomyocytes:

Forouzandehmehr2026: A computational whole-cell model of hiPSC-derived cardiomyocytes incorporating an empirically constrained oxygen consumption formulation for simulating pericellular oxygen dynamics in control and drug-induced conditions.

Forouzandehmehr2024

Forouzandehmehr2022

Forouzandehmehr2021

A mathematical model of Piezo1 mechanosensitive channel

An extracellular oxygen dynamics model for cardiomyocytes

• Review Editor, Frontiers in Network Physiology (Mar 2024–Present).

• Horizon Europe project SMASH-HCM consortium member (Jan 2024-Present): Advising on validated in silico models and decision support systems work packages.

• Organizing committee member of Computing in Cardiology 2022 conference, Sep 2022.

Nature: signal transduction and targeted therapy

The Journal of Physiology

Computers in Biology and Medicine

Frontiers in Bioengineering and Biotechnology

Frontiers in Pharmacology

Scientific Reports

Frontiers in Cardiovascular Medicine

International Journal for Numerical Methods in Biomedical Engineering

Frontiers in Network Physiology

Engineering in Life Sciences

Biotechnology Letters

• Invited case lecture for Tampere University-Graz University of Technology Modeling of Physiological Systems course, Host: Dr. Jussi Koivumäki, April 2026.

• Kavli Institute for Theoretical Physics, Multi-Scale Physics of Normal and Diseased Heart Program, Title of talk: "Systems-Level Transcriptomics Reveals Pathway-Selective Translational Alignment Across Murine Models of Cardiometabolic HFpEF", April 2026.

• George Washington University, Department of Biomedical Engineering, Cardiac Optogenetics and Optical Imaging Laboratory, Host: Dr. Emilia Entcheva, September 2025.

• UC Davis Department of Pharmacology, Grandi's Lab, Title of talk: "Electro-mechano-energetic coupling in mathematical models of cardiac cells", Host: Dr. Ele Grandi, April 2024.

• Yale School of Medicine, Myocardial Biology Seminar, Title of talk: "Evolution of computer models of human induced pluripotent stem cell-derived cardiomyocytes". Host: Dr. Fadi Akar, April 2023.

• Simula Research Laboratory, Title of talk: "The Comparison Between Two Mathematical Contractile Elements Integrated into an hiPSC-CM In-silico Model". Hosts: Dr. Aslak Tveito and Dr. Samuel Wall, Dec 2019.

• Doctoral Dissertation Award by Industrial Research Fund at Tampere University of Technology: Top three doctoral dissertation of Faculty of Medicine and Health Technology in 2024, €1500, Apr 2025.

• Full membership nomination, Sigma Xi, The Scientific Research Honor Society, Mar 2025.

• Finnish Cultural Foundation: PostDoc Pool Award, "Advancing metabolite-sensitive mathematical modeling of cardiomyocytes pathophysiology toward sex-difference capacity.", 22 selected among 116 applicants nationwide, May 2024.

• Invited Review Editor for Frontiers in Network Physiology, Mar 2024.

• Doctoral thesis “Mathematical Modeling of Cardiomyocytes Pathophysiology and Biomechanics” distinction recognition, Feb 2024.

• Paavo Nurmi Foundation Grant for a computational investigation of mechano-sensitive channel Piezo1 pathophysiology in R403Q hypertrophic cardiomyopathy, €6,000, Dec 2023.

• Predoctoral United States permanent residence (EB2-NIW) granted from overseas based on academic merit, Sep 2023.

• Joint WG e-Cardiology European Society of Cardiology – Computing in Cardiology: Clinical Needs Translational Award, Sep 2022.

• MET Faculty of Tampere University and Tampere University Foundation Travel Grants, €2700, 2019-2023.

• Tampere University Center of Excellence in Body on Chip (CoEBoC), “Best in Publishing” Recognition, Dec 2022.

• Finnish Cultural Foundation Pirkanmaa Grant, May 2022, secured funding > €26,000.

• Full 4-year DSc scholarship from Faculty of Medicine and Health Technology of Tampere University, 4 selected among 113 applicants received globally, Jan 2019, secured funding > €120,000.

• University of Oxford Pembroke College Access Award, May 2020.