Research
Post-IMCR Modifications
Asymmetric Synthesis of Functionalized 2,5-Pyrrolidinediones and β-Lactams through Diastereospecific Cycloisomerization/ Rearrangements of Chiral Ethanolamine Derived Ugi Adducts
Alkaloid-Mimicking Tricyclic Skeletons by Diastereo- and Regioselective Ugi/ipso-Cyclization/Aza-Michael Cascade Reaction in One-Pot
Asymmetric Synthesis
Stereoselective synthesis of functionalized 1,2,3,4-tetrahydroisoquinolines (THIQs) via highly diastereoselective Ugi three-component reactions (U3CR) with chiral 3,4-dihydroisoquinolines (DHIQs)
C-H Bond Functionalizations
Transition-Metal-Free Oxidative Cross Coupling of Methylhetarenes with Imidazoheterocycles towards Efficient C(sp2)-H Carbonylation
Photocatalytic Heterocyclic Synthesis
An Efficient Synthesis of 2-Substituted Benzimidazoles via Photocatalytic Condensation of o-phenylenediamine and Aldehydes
Drug Discovery
Design, synthesis and biological evaluations of chirally pure 1,2,3,4-tertrahydroisoquinoline analogs as anti-cancer agents
Development of constrained tamoxifen mimics and their antiproliferative properties against breast cancer cells
Investigation of podophyllotoxin esters as potential anticancer agents: Synthesis, biological studies and tubulin inhibition properties
