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AIDS AWARNESS
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AIDS AWARNESS
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  • HIV
  • HSV
  • HBSAG
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    • HIV
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    • HBSAG

What is HIV and AIDS? 

Definition

Human immunodeficiency virus (HIV) is the virus that causes acquired immunodeficiency syndrome (AIDS). When a person becomes infected with HIV, the virus attacks and weakens the immune system. As the immune system weakens, the person is at risk of getting life-threatening infections and cancers. When that happens, the illness is called AIDS. Once a person has the virus, it stays inside the body for life.

The virus is NOT spread by:

  • Casual contact, such as hugging or closed-mouth kissing

  • Mosquitoes or pets

  • Participating in sports

  • Touching items that were touched by a person infected with the virus

  • Eating food handled by a person with HIV

HIV and blood or organ donation:

  • HIV is not spread to a person who donates blood or organs. People who donate organs are never in direct contact with the people who receive them. Likewise, a person who donates blood is never in contact with the person receiving it. In all of these procedures, sterile needles and instruments are used.

  • Blood banks and organ donor programs thoroughly check (screen) donors, blood, and tissues. It is very unlikely to get HIV from blood transfusions, blood products, or organ or tissue transplants.

Risk factors for getting HIV include:

  • Having unprotected anal or vaginal sex. Receptive anal sex is the riskiest. Having multiple partners also increases the risk. Using a new condom correctly every time you have sex greatly helps lower this risk.

  • Using drugs and sharing needles or syringes.

  • Having a sexual partner with HIV who is not taking HIV medicines.

  • Having a sexually-transmitted disease (STD).

Symptoms

Symptoms related to acute HIV infection (when a person is first infected) can be similar to the flu or other viral illnesses. They include:

  • Fever and muscle pains

  • Headache

  • Sore throat

  • Night sweats

  • Mouth sores, including yeast infection (thrush)

  • Swollen lymph glands

  • Diarrhea

Many people have no symptoms when they are first infected with HIV.

Acute HIV infection (Stage 1) progresses over a few weeks to months to become chronic or asymptomatic HIV infection (Stage 2) (no symptoms). This stage can last 10 years or longer. During this period, the person might have no reason to suspect they have HIV, but they can spread the virus to others.

If they are not treated, almost all people infected with HIV will develop AIDS (Stage 3). Some people develop AIDS within a few years of infection. Others remain completely healthy after 10 or even 20 years (called long-term nonprogressors).

People with AIDS have had their immune system damaged by HIV. They are at very high risk of getting infections that are uncommon in people with a healthy immune system. These infections are called opportunistic infections and can affect any part of the body. These can be caused by:

  • Bacteria

  • Viruses

  • Fungi

  • Protozoa

People with AIDS are also at higher risk for certain cancers, especially lymphomas and a skin cancer called Kaposi sarcoma.

Symptoms depend on the particular infection and which part of the body is infected.

Lung infections are common in AIDS and often cause cough, fever, and shortness of breath.

Intestinal infections are also common and can cause:

  • Diarrhea

  • Abdominal pain

  • Vomiting

  • Swallowing problems

Other common symptoms in people with HIV infection and AIDS include:

  • Weight loss

  • Fever

  • Sweats

  • Rashes

  • Swollen lymph glands

Exams and Tests

There are tests that are done to check if you've been infected with the virus.

DIAGNOSTIC TESTS

In general, testing is a 2-step process:

  • Screening test -- There are several kinds of tests. Some are blood tests, others are mouth fluid tests. They check for antibodies to the HIV virus, HIV antigen, or both. Some screening tests can give results in 30 minutes or less.

  • Follow-up test -- This is also called a confirmatory test. It is often done when the screening test is positive.

Home tests are available to test for HIV. If you plan to use one, check to make sure it is approved by the FDA. Follow instructions on the packaging to ensure the results are as accurate as possible.

The Centers for Disease Control and Prevention (CDC) recommends that everyone ages 15 to 65 have a screening test for HIV. People with risky behaviors should be tested regularly. Pregnant women should also have a screening test.

TESTS AFTER BEING DIAGNOSED WITH HIV

People with AIDS should have regular blood tests to check their CD4 cell count:

  • CD4 T cells are the blood cells that HIV attacks. They are also called T4 cells or "helper T cells."

  • As HIV damages the immune system, the CD4 count drops. A normal CD4 count is from 500 to 1,500 cells/mm3 of blood.

  • People usually develop symptoms when their CD4 count drops below 350. More serious complications occur when the CD4 count drops to 200. When the count is below 200, the person is said to have AIDS.

Other tests include:

  • HIV RNA level, or viral load, to check how much HIV is in the blood

  • A resistance test to see if the virus has any changes in the genetic code that would lead to resistance to the medicines used to treat HIV

  • Complete blood count, blood chemistry, and urine test

  • Tests for other sexually transmitted infections

  • TB test

  • Pap smear to check for cervical cancer

  • Anal Pap smear to check for cancer of the anus


Treatment

HIV/AIDS is treated with medicines that stop the virus from multiplying. This treatment is called antiretroviral therapy (ART).

In the past, people with HIV infection would start antiretroviral treatment after their CD4 count dropped or they developed HIV complications. Today, HIV treatment is recommended for all people with HIV infection, even if their CD4 count is still normal.

There are two types or treatment:

  • Pills are given to people who are just starting treatment.

  • Shots may be given to people who have an undetectable viral load or who have been virally suppressed for at least 3 months. Shots may be given every month or every other month.

Regular blood tests are needed to make sure the virus level in the blood (viral load) is kept low or suppressed. The goal of treatment is to lower the HIV virus in the blood to a level that is so low that the test can't detect it. This is called an undetectable viral load.

If the CD4 count already dropped before treatment was started, it will usually slowly go up. HIV complications often disappear as the immune system recovers.


Alternative Names

HIV infection; Infection - HIV; Human immunodeficiency virus; Acquired immune deficiency syndrome: HIV-1

Causes

The virus is spread (transmitted) person-to-person through certain body fluids:

  • Blood

  • Semen and preseminal fluid

  • Rectal fluids

  • Vaginal fluids

  • Breast milk

HIV can be spread if these fluids come in contact with:

  • Mucous membranes (inside of the mouth, penis, vagina, rectum)

  • Damaged tissue (tissue that has been cut or scraped)

  • Injection into the blood stream

HIV cannot be spread through sweat, saliva, or urine.

HIV is mainly spread:

  • Through vaginal or anal sex with someone who has HIV without using a condom or is not taking medicines to prevent or treat HIV

  • Through needle sharing or other equipment used to inject drugs with someone who has HIV

Less often, HIV is spread:

  • From mother to child. A pregnant woman can spread the virus to her fetus through their shared blood circulation, or a nursing mother can pass it to her baby through her breast milk. Testing and treatment of HIV-positive mothers has helped lower the number of babies getting HIV.

  • Through needle sticks or other sharp objects that are contaminated with HIV (mainly health care workers).


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