PEGylated amphiphilic block co-polymers encapsulate myriad small molecule drugs, including PARP, HDAC, and other inhibitors. They exhibit a long circulation time and have stealth properties conferred by the incorporation of PEG. They can also be adorned with cell-specific targeting molecules

Two compartment system with a lipid bilayer and an aqueous core. Used to encapsulate hydrophilic drugs, and hydrophobic drugs may also be incorporated into the membrane. Additionally, liposomes can be decorated with PEG and targeting molecules. These can be formulated to induce stimulti responsive drug release

A solid lipid core complexed around the DNA/RNA phosphate backbone, with its tails intercalating within a lipid membrane shell. These are used primarily to encapuslate oligonucleotide based therapies. They are PEGylated and can accomodate tageting moieties.

NPs with spacially/phase separated multifunctional ligands or matierals. These are particularly useful multimodal therapies such as imaging, theranostic, and stimuli release NPs. They form asymettric structures cofferring multiple properties. We are developing Janus NPs using transition metals with dual diagnositc and therapudic conjugated moiteies.

Core-shell spherical NPs. Polymer core with lipid membrane shell. It facilitates a wide variety of drugs and their combinations. The lipid layer adds layer of protection to the particle, helpful in some applications. Functionalized onto the membrane surface, are differt targeting moieties such as anitbodies, aptamers, or other targeting ligands like sugars, folic, hyaluronic and lactic acids.