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Sobre mí [About Me]

With over 12 years of expertise in market research across the vibrant and diverse markets of Latin America. My journey has taken me across the continent, allowing me to live and work in Colombia, Mexico, and Argentina. These experiences have enriched my understanding of the nuanced cultural differences and shared values within the Spanish-speaking world.

My career has been dedicated to understanding and bridging these cultural gaps, helping individuals and businesses connect more authentically with the Hispanic community. Whether you're looking to improve your Spanish for personal or professional reasons, I bring a wealth of real-world experience and cultural insights to the table

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Our services are available from 8:00 AM to 8:00 PM, Monday through Saturday.

agucatestone@gmail.com

My experience in Healthcare!

Origin: Bogotá, Colombia.

Education: Technical and university studies in Bogotá.

Professional Experience:

Worked for major companies in Latin America, developing a deep qualitative and quantitative understanding of cultures in LATAM.

- Market Research in the Pharmaceutical Industry:

January 2015, Mexico, Selected to investigate and learn more about the pharmaceutical market and conduct patient data analysis, patient satisfaction studies, and medical strategy evaluations.

Return to Colombia: and for the follow 5 years, Developed qualitative and ethnographic knowledge about Latin American populations, focusing on oncology, autoimmune diseases, and chronic conditions. Assessed competitive contexts and monitored the perception and image of pharmaceutical products, healthcare providers, and patient associations. Connected with healthcare providers and patient associations.

Worked for 3 years in Argentina, bringing healthcare expertise and expanding knowledge of Southern Cone countries.

Gained a comprehensive understanding of the culture and diversity of Spanish speakers in the Americas.

Focused on improving patient satisfaction and healthcare service delivery.

How Your Experience Can Help Improve Spanish with Patients and Colleagues:

Improving Communication with Patients:
- Apply your experience in patient satisfaction and needs to personalize and improve care in Spanish.
- Utilize your market research knowledge to understand better barriers and challenges in communicating with Spanish-speaking patients.
Contextualizing Treatments and Services:
- Adapt medical and marketing strategies to the cultural and linguistic specifics of Spanish-speaking patients.
- Enhance patient-centered health education and communication using your experience with various diseases and treatments.

Areas of Healthcare expertise

Oncology

Breast Cancer
- Staging:
  - Stage II: Larger tumors or spread to nearby lymph nodes
  - Stage III: Locally advanced cancer with more extensive spread to lymph nodes
  - Stage IV: Metastatic breast cancer (spread to distant organs)
- Subtypes: Ductal carcinoma, lobular carcinoma, triple-negative breast cancer, HER2-positive breast cancer.
- Biomarkers and Mutations:
  - HER2 (Human Epidermal Growth Factor Receptor 2): Overexpression associated with aggressive disease.
  - Estrogen Receptor (ER) and Progesterone Receptor (PR): Hormone receptor-positive cancers.
  - BRCA1 and BRCA2: Genetic mutations linked to higher risk of breast and ovarian cancer.
  - Ki-67: Marker of cell proliferation.
Lung Cancer
- Staging:
  - Stage I: Small, localized tumor
  - Stage II: Tumor larger or spread to nearby lymph nodes
  - Stage III: Extensive regional spread
  - Stage IV: Metastatic cancer (spread to distant organs)
- Subtypes: Non-small cell lung cancer (NSCLC), small cell lung cancer (SCLC).
- Biomarkers and Mutations:
  - EGFR (Epidermal Growth Factor Receptor): Mutations associated with NSCLC.
  - ALK (Anaplastic Lymphoma Kinase): Rearrangements in NSCLC.
  - KRAS: Mutations linked to poor prognosis in NSCLC.
  - PD-L1 (Programmed Death-Ligand 1): Expression level used to determine response to immunotherapy.
Bladder Cancer
- Staging:
  - Stage 0: Non-invasive (superficial) cancer
  - Stage I: Tumor invades the inner layer of the bladder
  - Stage II: Tumor invades the muscle layer of the bladder
  - Stage III: Tumor extends beyond the bladder to surrounding tissues
  - Stage IV: Metastatic cancer (spread to distant organs)
- Subtypes: Transitional cell carcinoma, squamous cell carcinoma, adenocarcinoma.
- Biomarkers and Mutations:
  - FGFR3 (Fibroblast Growth Factor Receptor 3): Mutations common in non-invasive bladder cancer.
  - TP53: Mutations associated with invasive bladder cancer.
  - UroVysion FISH (Fluorescence In Situ Hybridization): Detects genetic abnormalities in bladder cancer.
Kidney Cancer
- Staging:
  - Stage I: Tumor confined to the kidney
  - Stage II: Tumor larger but still confined to the kidney
  - Stage III: Tumor has spread to regional lymph nodes
  - Stage IV: Metastatic cancer (spread to distant organs)
- Subtypes: Renal cell carcinoma (RCC), transitional cell carcinoma, Wilms tumor.
- Biomarkers and Mutations:
  - VHL (Von Hippel-Lindau): Mutations associated with clear cell RCC.
  - PBRM1 (Polybromo-1): Mutations in RCC.
  - MET (Mesenchymal-Epithelial Transition Factor): Amplification linked to poor prognosis in RCC.
Melanomas Metastásicos
- Staging:
  - Stage I: Localized melanoma
  - Stage II: Local melanoma with deeper invasion
  - Stage III: Regional spread to lymph nodes
  - Stage IV: Metastatic melanoma (spread to distant organs)
- Biomarkers and Mutations:
  - BRAF: Mutations (e.g., BRAF V600E) commonly found in melanoma.
  - NRAS: Mutations associated with resistance to certain therapies.
  - KIT: Mutations found in a subset of melanoma cases.
Carcinomas Basocelulares (Basal Cell Carcinoma)
- Staging:
  - Stage 0: In situ (confined to the skin surface)
  - Stage I: Localized to the skin, small size
  - Stage II: Larger size or locally invasive
  - Stage III: More extensive or deep invasion
  - Stage IV: Rarely, metastatic
- Biomarkers and Mutations:
  - PTCH1 (Patched 1): Mutations associated with basal cell nevus syndrome.
  - SMO (Smoothened): Mutations involved in the Hedgehog signaling pathway.
Skin Cancer
- Staging:
  - Stage 0: In situ (confined to the skin surface)
  - Stage I: Localized and small
  - Stage II: Larger or deeper
  - Stage III: Regional spread to lymph nodes
  - Stage IV: Metastatic (spread to distant organs)
- Subtypes: Basal cell carcinoma, squamous cell carcinoma, melanoma.
- Biomarkers and Mutations:
  - p53: Commonly mutated in squamous cell carcinoma.
  - BRAF: Mutations found in melanoma and some skin cancers.
  - NRAS: Mutations found in melanoma and non-melanoma skin cancers.
Lymphomas
- Staging:
  - Stage I: Single lymph node region or organ
  - Stage II: Two or more lymph node regions on one side of the diaphragm
  - Stage III: Lymph node regions on both sides of the diaphragm
  - Stage IV: Metastatic lymphoma (spread to distant organs)
- Subtypes: Hodgkin lymphoma, non-Hodgkin lymphoma.
- Biomarkers and Mutations:
  - Reed-Sternberg Cells: Found in Hodgkin lymphoma.
  - BCL2 (B-cell lymphoma 2): Overexpression associated with follicular lymphoma.
  - MYC: Rearrangements found in Burkitt lymphoma.
Leukemias
- Staging:
  - Acute Leukemias: Rapid progression, classified by type (ALL, AML)
  - Chronic Leukemias: Slow progression, classified by type (CLL, CML)
- Subtypes: Acute lymphocytic leukemia (ALL), chronic lymphocytic leukemia (CLL), acute myeloid leukemia (AML), chronic myeloid leukemia (CML).
- Biomarkers and Mutations:
  - Philadelphia Chromosome (BCR-ABL): Found in CML.
  - FLI1: Associated with Ewing’s sarcoma.
  - NPM1 and FLT3: Mutations found in AML.
Bone Cancer
- Staging:
  - Stage I: Localized tumor
  - Stage II: Localized tumor with more extensive growth
  - Stage III: Regional spread to nearby tissues
  - Stage IV: Metastatic cancer (spread to distant organs)
- Subtypes: Osteosarcoma, Ewing's sarcoma, chondrosarcoma.
- Biomarkers and Mutations:
  - TP53: Mutations linked to osteosarcoma.
  - EWS-FLI1 Fusion Protein: Associated with Ewing's sarcoma.
  - IDH1/IDH2: Mutations found in chondrosarcoma.

Oncology

Breast Cancer
- Staging:
  - Stage II: Larger tumors or spread to nearby lymph nodes
  - Stage III: Locally advanced cancer
  - Stage IV: Metastatic breast cancer
- Subtypes: HER2 +and -, HR +and -, triple-negative breast cancer. In neoadyuvant and adyuvant
Lung Cancer
- Staging:
  - Stage III: Extensive regional spread
  - Stage IV: Metastatic cancer (spread to distant organs)
- Subtypes: Non-small cell lung cancer (NSCLC), small cell lung cancer (SCLC). ALK,EGFR, KRAS AND PDL -L1
Bladder Cancer
- Staging:
  - Stage 0: Non-invasive (superficial) cancer
  - Stage I: Tumor invades the inner layer of the bladder
  - Stage II: Tumor invades the muscle layer of the bladder
  - Stage III: Tumor extends beyond the bladder to surrounding tissues
  - Stage IV: Metastatic cancer (spread to distant organs)
- Subtypes: Transitional cell carcinoma, squamous cell carcinoma, adenocarcinoma.
Kidney Cancer
- Staging:
  - Stage I: Tumor confined to the kidney
  - Stage II: Tumor larger but still confined to the kidney
  - Stage III: Tumor has spread to regional lymph nodes
  - Stage IV: Metastatic cancer (spread to distant organs)
- Subtypes: Renal cell carcinoma (RCC), transitional cell carcinoma, Wilms tumor.
Melanomas Metastásicos (BRAF)
- Staging:
  - Stage I: Localized melanoma
  - Stage II: Local melanoma with deeper invasion
  - Stage III: Regional spread to lymph nodes
  - Stage IV: Metastatic melanoma (spread to distant organs)
Carcinomas Basocelulares (Basal Cell Carcinoma) (BRAF)
- Staging:
  - Stage 0: In situ (confined to the skin surface)
  - Stage I: Localized to the skin, small size
  - Stage II: Larger size or locally invasive
  - Stage III: More extensive or deep invasion
  - Stage IV: Rarely, metastatic
Skin Cancer
- Staging:
  - Stage 0: In situ (confined to the skin surface)
  - Stage I: Localized and small
  - Stage II: Larger or deeper
  - Stage III: Regional spread to lymph nodes
  - Stage IV: Metastatic (spread to distant organs)
- Subtypes: Basal cell carcinoma, squamous cell carcinoma, melanoma.
Lymphomas
- Staging:
  - Stage I: Single lymph node region or organ
  - Stage II: Two or more lymph node regions on one side of the diaphragm
  - Stage III: Lymph node regions on both sides of the diaphragm
  - Stage IV: Metastatic lymphoma (spread to distant organs)
- Subtypes: Hodgkin lymphoma, non-Hodgkin lymphoma.
Leukemias
- Staging:
  - Acute Leukemias: Rapid progression, classified by type (ALL, AML)
  - Chronic Leukemias: Slow progression, classified by type (CLL, CML)
- Subtypes: Acute lymphocytic leukemia (ALL), chronic lymphocytic leukemia (CLL), acute myeloid leukemia (AML), chronic myeloid leukemia (CML).
Bone Cancer
- Staging:
  - Stage I: Localized tumor
  - Stage II: Localized tumor with more extensive growth
  - Stage III: Regional spread to nearby tissues
  - Stage IV: Metastatic cancer (spread to distant organs)
- Subtypes: Osteosarcoma, Ewing's sarcoma, chondrosarcoma.

Cardiometabolic

Chronic Heart Failure
- Classification:
  - Class I: No limitation of physical activity
  - Class II: Slight limitation of physical activity
  - Class III: Marked limitation of physical activity
  - Class IV: Unable to carry out any physical activity without discomfort
Diabetes
- Classification:
  - Type 1 Diabetes: Insulin-dependent, autoimmune destruction of beta cells
  - Type 2 Diabetes: Insulin resistance and relative insulin deficiency
  - Gestational Diabetes: Diabetes occurring during pregnancy
Obesity
- Classification:
  - BMI 30-34.9: Obesity Class I
  - BMI 35-39.9: Obesity Class II
  - BMI 40 or higher: Obesity Class III (severe or morbid obesity)

Autoimmune

Psoriasis
- Subtypes: Plaque psoriasis, guttate psoriasis, inverse psoriasis, pustular psoriasis, erythrodermic psoriasis.
Arthritis
- Subtypes: Rheumatoid arthritis, osteoarthritis, psoriatic arthritis.
Multiple Sclerosis (MS)
- Classification:
  - Relapsing-Remitting MS (RRMS): Characterized by flare-ups
  - Primary Progressive MS (PPMS): Steady progression without remission
  - Secondary Progressive MS (SPMS): Progression after initial RRMS
  - Progressive-Relapsing MS (PRMS): Progressive from the start with relapses
Hidradenitis Suppurativa
- Staging:
  - Stage I: Abscess formation
  - Stage II: Recurrent abscesses with sinus tracts
  - Stage III: Multiple interconnected sinus tracts and abscesses
Psoriatic Arthritis
- Classification:
  - Peripheral Psoriatic Arthritis: Affects limbs
  - Axial Psoriatic Arthritis: Affects spine and pelvis
Idiopathic Macular Degeneration
- Stages:
  - Early: Drusen and pigmentary changes
  - Intermediate: Larger drusen, more significant retinal changes
  - Late (Dry or Wet): Geographic atrophy or choroidal neovascularization

Sexual and Reproductive Health

HIV
- Stages:
  - Acute HIV Infection: Acute retroviral syndrome
  - Chronic HIV Infection: Clinical latency phase
  - AIDS: Advanced HIV with opportunistic infections
Hepatitis
- Types: Hepatitis A, B, C, D, E
Contraceptives
- Types: Oral contraceptives, intrauterine devices (IUDs), condoms, implants

Aesthetics

Botulinum Toxin
- Uses: Wrinkle reduction, chronic migraine, hyperhidrosis
Fillers
- Types: Hyaluronic acid fillers, collagen fillers, calcium hydroxylapatite

Growth Hormone Deficiency

Classification:
- Childhood Growth Hormone Deficiency: Poor growth rates
- Adult Growth Hormone Deficiency: Increased fat, decreased muscle mass

Hemophilia

Types:
- Hemophilia A: Factor VIII deficiency
- Hemophilia B: Factor IX deficiency

Osteoporosis

Classification:
- T-score -1 to -2.5: Osteopenia (low bone mass)
- T-score -2.5 or lower: Osteoporosis

Chronic Migraine

Classification:
- Chronic Migraine: Headaches occurring 15 or more days per month for at least three months

Post-Stroke

Classification:
- Acute Phase: Initial 24-48 hours
- Subacute Phase: First 1-3 months
- Chronic Phase: Beyond 3 months

Alopecia

Types:
- Alopecia Areata: Sudden loss of small patches of hair
- Androgenic Alopecia: Pattern hair loss, typically male and female pattern baldness
- Alopecia Totalis: Total loss of scalp hair

Achondroplasia

Classification:
- Infantile: Characterized by disproportionate shortening of the long bones
- Adult: Short stature, normal-sized torso

Respiratory

Asthma
- Classification:
  - Intermittent: Symptoms less than twice a week
  - Mild Persistent: Symptoms more than twice a week
  - Moderate Persistent: Daily symptoms and nocturnal symptoms more than once a week
  - Severe Persistent: Continuous symptoms and frequent nighttime symptoms

Neurology

Epilepsy
- Types:
  - Focal Seizures: Affect one area of the brain
  - Generalized Seizures: Affect both sides of the brain
  - Unknown Onset Seizures: Seizures with an unclear origin

Ophthalmology

Glaucoma
- Types:
  - Open-Angle Glaucoma: Gradual loss of vision
  - Angle-Closure Glaucoma: Sudden vision loss with severe pain
  - Normal-Tension Glaucoma: Optic nerve damage despite normal eye pressure

Hematology

Anemia
- Types:
  - Iron-Deficiency Anemia: Lack of iron
  - Vitamin B12 Deficiency Anemia: Lack of vitamin B12
  - Folate Deficiency Anemia: Lack of folic acid
  - Aplastic Anemia: Bone marrow failure

Companies supported through my consulting experience

Patient asotiations in Colombia

Patient asotiations in Argentina

All Can

Sanitas (Colombia)

Novartis

Roche

Sanofi

Pfizer

Allergan

Roche

Biotech

Bristol Mayers Squid (Bms)

Abbvie

Jhonson & jhonson Medical devices

Janssen

Biogen

Glaxo Smith Kline (GSK)

Novo Nordisk

Amgen

PEER-REVIEWED PUBLICATIONS

Qualitative Study on Barriers to Access from the Perspective of Patients and OncologistsQualitative Study on Barriers to Access from the Perspective of Patients and Oncologists

International Journal of Innovative Science and Research Technology · Jul 27, 2021

https://ijisrt.com/qualitative-study-on-barriers-to-access-from-the-perspective-of-patients-and-oncologists

Julia Ismael; Andrey Mendez; Pablo Gandino; Ignacio Zerviño; María Gabriela Berta; Emilia Arrighi; María Alejandra Iglesias; Haydee Gonzalez; Mariana Auad

Scribd : https://bit.ly/3kZfmWx

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