Publications: 

Research Papers:

1.PMID: 38990623

Influence of intraocular inflammatory cytokine levels on postoperative complications in congenital cataract surgery.

Kaur S, Sharma SP, Sukhija J, Ram J, Singh N.Indian J Ophthalmol. 2024 Dec 1;72(12):1757-1760. doi: 10.4103/IJO.IJO_218_24. Epub 2024 Jul 11.PMID: 38990623 Free PMC article.

2. PMID: 38131536

Predicting visual outcomes following anti-vascular endothelial growth factor treatment for diabetic macular edema.

Rana V, Agarwal A, Arora A, Bansal R, Dogra M, Bhadada SK, Singh N, Gupta V.Indian J Ophthalmol. 2024 Jan 1;72(Suppl 1):S16-S21. doi: 10.4103/IJO.IJO_893_23. Epub 2023 Dec 22.PMID: 38131536 Free PMC article. Clinical Trial.

3.PMID: 36547708

Correlation of angiogenic growth factors and inflammatory cytokines with the clinical phenotype of ocular tuberculosis.

Kumar A, Singh R, Sharma RK, Sharma SP, Agarwal A, Gupta V, Singh R, Katoch D, Singh N.Graefes Arch Clin Exp Ophthalmol. 2023 May;261(5):1369-1380. doi: 10.1007/s00417-022-05943-9. Epub 2022 Dec 22.PMID: 36547708

4. PMID: 35513467

Axial myopia, a protective factor for diabetic retinopathy-role of vascular endothelial growth factor.

Kulshrestha A, Singh N, Moharana B, Gupta PC, Ram J, Singh R.Sci Rep. 2022 May 5;12(1):7325. doi: 10.1038/s41598-022-11220-w.PMID: 35513467 Free PMC article.

5. PMID: 34526297

CYP1B1 and MYOC variants in neonatal-onset versus infantile-onset primary congenital glaucoma.

Kaushik S, Luthra-Guptasarma M, Prasher D, Dhingra D, Singh N, Kumar A, Sharma SP, Kaur H, Snehi S, Thattaruthody F, Pandav SS.Br J Ophthalmol. 2023 Feb;107(2):227-233. doi: 10.1136/bjophthalmol-2020-318563. Epub 2021 Sep 15.PMID: 34526297

6. PMID: 33754210

Corneal reconstruction in chemically damaged cornea using temperature responsive surface assisted mesenchymal stem cell transplantation in rabbits.

Sharma J, Sharma RK, Gupta P, Gupta N, Singh N.Graefes Arch Clin Exp Ophthalmol. 2021 Jul;259(7):1859-1870. doi: 10.1007/s00417-021-05132-0. Epub 2021 Mar 22.PMID: 33754210

7. PMID: 33359883

Proteomic profile of vitreous in patients with tubercular uveitis.

Bansal R, Khan MM, Dasari S, Verma I, Goodlett DR, Manes NP, Nita-Lazar A, Sharma SP, Kumar A, Singh N, Chakraborti A, Gupta V, Dogra MR, Ram J, Gupta A.Tuberculosis (Edinb). 2021 Jan;126:102036. doi: 10.1016/j.tube.2020.102036. Epub 2020 Dec 3.PMID: 33359883

8. PMID: 33045217

Neonatal-Onset Congenital Ectropion Uveae: A Distinct Phenotype of Newborn Glaucoma.

Kaushik S, Dhingra D, Vibha B, Saini A, Gupta G, Snehi S, Singh N, Thattaruthody F, Pandav SS.Am J Ophthalmol. 2021 Mar;223:83-90. doi: 10.1016/j.ajo.2020.10.001. Epub 2020 Oct 9.PMID: 33045217

9. PMID: 32603726

Collaborative Ocular Tuberculosis Study Consensus Guidelines on the Management of Tubercular Uveitis-Report 2: Guidelines for Initiating Antitubercular Therapy in Anterior Uveitis, Intermediate Uveitis, Panuveitis, and Retinal Vasculitis.

Agrawal R, Testi I, Bodaghi B, Barisani-Asenbauer T, McCluskey P, Agarwal A, Kempen JH, Gupta A, Smith JR, de Smet MD, Yuen YS, Mahajan S, Kon OM, Nguyen QD, Pavesio C, Gupta V; Collaborative Ocular Tuberculosis Study Consensus Group.Ophthalmology. 2021 Feb;128(2):277-287. doi: 10.1016/j.ophtha.2020.06.052. Epub 2020 Jun 27.PMID: 32603726

10. PMID: 32250731

The Collaborative Ocular Tuberculosis Study (COTS) Consensus (CON) Group Meeting Proceedings.

Agrawal R, Testi I, Mahajan S, Yuen YS, Agarwal A, Rousselot A, Raje D, Gunasekeran DV, Kon OM, Barisani-Asenbauer T, Kempen JH, Gupta A, Jabs DA, Smith JR, Bodaghi B, Zierhut M, DeSmet M, Cluskey PM, Agarwal M, Agarwal M, Aggarwal K, Agrawal M, Al-Dhibi H, Androudi S, Asyari F, Balasundaram MB, Murthy KB, Baglivo E, Banker A, Bansal R, Basu S, Behera D, Biswas J, Carreño E, Caspers L, Chee SP, Chhabra R, Cimino L, Del Rio LEC, Cunningham ET, Curi ALL, Das D, Denisova E, Denniston AK, Errera MH, Fonollosa A, George A, Goldstein DA, Crosier YG, Gurbaxani A, Invernizzi A, Isa HM, Md Islam S, Jones N, Katoch D, Khairallah M, Khosla A, Kramer M, Kumar A, Kumar A, Nora RD, Lee R, Lowder C, Luthra S, Mahendradas P, Makhoul D, Mazumdar S, Mehta S, Miserocchi E, Mochizuki M, Mohamed OS, Muccioli C, Munk MR, Murthy S, Narain S, Nascimento H, Neri P, Nguyen M, Okada AA, Ozdal P, Palestine A, Pichi F, Rathinam SR, Schlaen A, Sehgal S, Sen HN, Sharma A, Sharma K, Shoughy SS, Singh N, Singh R, Soheilian M, Sridharan S, Thorne JE, Tappeiner C, Teoh S, Tognon MS, Tugal-Tutkun I, Tyagi M, Uy H, Santos DVV, Valentincic NV, Westcott M, Yanai R, Alvarez BY, Zahedur R, Nguyen QD, Pavesio C, Gupta V.Ocul Immunol Inflamm. 2020 Sep 30;28(sup1):85-95. doi: 10.1080/09273948.2020.1716025. Epub 2020 Apr 6.PMID: 32250731

11. PMID: 32160084

Mycobacterium Tuberculosis Modulates Fibroblast Growth Factor and Vascular Endothelial Growth Factor in Ocular Tuberculosis.

Singh N, Singh R, Sharma RK, Kumar A, Sharma SP, Agarwal A, Gupta V, Singh R, Katoch D.Ocul Immunol Inflamm. 2021 Nov 17;29(7-8):1445-1451. doi: 10.1080/09273948.2020.1734212. Epub 2020 Mar 11.PMID: 32160084

12. PMID: 32115264

Collaborative Ocular Tuberculosis Study Consensus Guidelines on the Management of Tubercular Uveitis-Report 1: Guidelines for Initiating Antitubercular Therapy in Tubercular Choroiditis.

Agrawal R, Testi I, Mahajan S, Yuen YS, Agarwal A, Kon OM, Barisani-Asenbauer T, Kempen JH, Gupta A, Jabs DA, Smith JR, Nguyen QD, Pavesio C, Gupta V; Collaborative Ocular Tuberculosis Study Consensus Group.Ophthalmology. 2021 Feb;128(2):266-276. doi: 10.1016/j.ophtha.2020.01.008. Epub 2020 Jan 11.PMID: 32115264

13. PMID: 31940227

Tear IL-6 and IL-10 levels in HLA-B27-Associated Uveitis and Its clinical Implications.

Kumar A, Sharma SP, Agarwal A, Gupta V, Katoch D, Sehgal S, Singh N.Ocul Immunol Inflamm. 2021 Feb 17;29(2):237-243. doi: 10.1080/09273948.2019.1704022. Epub 2020 Jan 15.PMID: 31940227

14. PMID: 31504463

Transcriptional signatures of Mycobacterium tuberculosis in mouse model of intraocular tuberculosis.

Abhishek S, Ryndak MB, Choudhary A, Sharma S, Gupta A, Gupta V, Singh N, Laal S, Verma I.Pathog Dis. 2019 Jul 1;77(5):ftz045. doi: 10.1093/femspd/ftz045.PMID: 31504463 Free PMC article.

15. PMID: 30333960

Transcriptional Profile of Mycobacterium tuberculosis in an in vitro Model of Intraocular Tuberculosis.

Abhishek S, Saikia UN, Gupta A, Bansal R, Gupta V, Singh N, Laal S, Verma I.Front Cell Infect Microbiol. 2018 Oct 2;8:330. doi: 10.3389/fcimb.2018.00330. eCollection 2018.PMID: 30333960 Free PMC article.

16. PMID: 30234851

Diagnostic and Therapeutic Challenges.

Agarwal A, Aggarwal K, Sharma K, Sharma A, Behera D, Sharma S, Singh N, Gupta A, Gupta V, Albini T.Retina. 2020 Jan;40(1):187-193. doi: 10.1097/IAE.0000000000002303.PMID: 30234851 No abstract available.

17. PMID: 30185832

Longitudinal analysis of serum cytokine profile among patients with tubercular multifocal serpiginoid choroiditis: a pilot study.

Agarwal A, Deokar A, Sharma R, Singh N, Aggarwal K, Sharma S, Singh R, Sharma A, Sharma K, Agrawal R, Bansal R, Gupta V.Eye (Lond). 2019 Jan;33(1):129-135. doi: 10.1038/s41433-018-0157-5. Epub 2018 Sep 5.PMID: 30185832 Free PMC article.

18. PMID: 29958045

Long-Term Outcomes of Oral Anti-Tubercular Therapy in Patient with Tubercular Dacryoadenitis: A Case Series.

Singh M, Gupta N, Zadeng Z, Singh N, Kaur M, Gupta P.Ocul Immunol Inflamm. 2019;27(6):1016-1022. doi: 10.1080/09273948.2018.1486437. Epub 2018 Jun 29.PMID: 29958045

19. PMID: 29020533

Choroidal Structural Changes in Tubercular Multifocal Serpiginoid Choroiditis.

Agarwal A, Agrawal R, Khandelwal N, Invernizzi A, Aggarwal K, Sharma A, Singh R, Bansal R, Sharma K, Singh N, Gupta V.Ocul Immunol Inflamm. 2018;26(6):838-844. doi: 10.1080/09273948.2017.1370650. Epub 2017 Oct 11.PMID: 29020533

20. PMID: 28834945

Diagnostic and Therapeutic Challenges.

Agarwal A, Sharma A, Aggarwal K, Singh N, Sharma K, Singh R, Bansal R, Gupta V, Cunningham ET Jr.Retina. 2018 Jul;38(7):1436-1441. doi: 10.1097/IAE.0000000000001811.PMID: 28834945 No abstract available.

21. PMID: 28318350

Clinical Course and Outcomes of Pediatric Tubercular Uveitis in North India.

Kaur S, Aggarwal K, Agarwal A, Suri D, Gupta A, Singh R, Bansal R, Singh S, Singh N, Gupta A, Gupta V.Ocul Immunol Inflamm. 2018;26(6):859-864. doi: 10.1080/09273948.2017.1296579. Epub 2017 Mar 20.PMID: 28318350

22. PMID: 27888495

An unusual presentation of intraocular tuberculosis in a monocular patient: clinicopathological correlation.

Aggarwal K, Agarwal A, Sehgal S, Sharma S, Singh N, Sharma K, Samanta R, Invernizzi A, Sharma A, Gupta V.J Ophthalmic Inflamm Infect. 2016 Dec;6(1):46. doi: 10.1186/s12348-016-0118-8. Epub 2016 Nov 25.PMID: 27888495 Free PMC article.

23. PMID: 27857488

Porosity of Bleb Capsule declines rapidly with Fluid Challenge.

Pandav SS, Ross CM, Thattaruthody F, Nada R, Singh N, Gautam N, Beirne S, Wallace GG, Sherwood MB, Crowston JG, Coote M.J Curr Glaucoma Pract. 2016 Sep-Dec;10(3):91-96. doi: 10.5005/jp-journals-10008-1208. Epub 2016 Oct 29.PMID: 27857488 Free PMC article.

24. PMID: 27467093

Role of Regulatory T Cells in Tubercular Uveitis.

Sharma RK, Gupta A, Kamal S, Bansal R, Singh N, Sharma K, Virk S, Sachdeva N.Ocul Immunol Inflamm. 2018;26(1):27-36. doi: 10.1080/09273948.2016.1196711. Epub 2016 Jul 28.PMID: 27467093

25. PMID: 25329693

Endometrial VEGF induces placental sFLT1 and leads to pregnancy complications.

Fan X, Rai A, Kambham N, Sung JF, Singh N, Petitt M, Dhal S, Agrawal R, Sutton RE, Druzin ML, Gambhir SS, Ambati BK, Cross JC, Nayak NR.J Clin Invest. 2014 Nov;124(11):4941-52. doi: 10.1172/JCI76864. Epub 2014 Oct 20.PMID: 25329693 Free PMC article.

26. PMID: 24582892

TGFβ and PDGF-B signaling blockade inhibits myofibroblast development from both bone marrow-derived and keratocyte-derived precursor cells in vivo.

Singh V, Jaini R, Torricelli AA, Santhiago MR, Singh N, Ambati BK, Wilson SE.Exp Eye Res. 2014 Apr;121:35-40. doi: 10.1016/j.exer.2014.02.013. Epub 2014 Feb 26.PMID: 24582892 Free PMC article.

27. PMID: 23795287

Photoreceptor avascular privilege is shielded by soluble VEGF receptor-1.

Luo L, Uehara H, Zhang X, Das SK, Olsen T, Holt D, Simonis JM, Jackman K, Singh N, Miya TR, Huang W, Ahmed F, Bastos-Carvalho A, Le YZ, Mamalis C, Chiodo VA, Hauswirth WW, Baffi J, Lacal PM, Orecchia A, Ferrara N, Gao G, Young-Hee K, Fu Y, Owen L, Albuquerque R, Baehr W, Thomas K, Li DY, Chalam KV, Shibuya M, Grisanti S, Wilson DJ, Ambati J, Ambati BK.Elife. 2013 Jun 18;2:e00324. doi: 10.7554/eLife.00324.PMID: 23795287 Free PMC article.

28. PMID: 23476047

Soluble vascular endothelial growth factor receptor 3 is essential for corneal alymphaticity.

Singh N, Tiem M, Watkins R, Cho YK, Wang Y, Olsen T, Uehara H, Mamalis C, Luo L, Oakey Z, Ambati BK.Blood. 2013 May 16;121(20):4242-9. doi: 10.1182/blood-2012-08-453043. Epub 2013 Mar 8.PMID: 23476047 Free PMC article.

29. PMID: 23464925

Targeted intraceptor nanoparticle therapy reduces angiogenesis and fibrosis in primate and murine macular degeneration.

Luo L, Zhang X, Hirano Y, Tyagi P, Barabás P, Uehara H, Miya TR, Singh N, Archer B, Qazi Y, Jackman K, Das SK, Olsen T, Chennamaneni SR, Stagg BC, Ahmed F, Emerson L, Zygmunt K, Whitaker R, Mamalis C, Huang W, Gao G, Srinivas SP, Krizaj D, Baffi J, Ambati J, Kompella UB, Ambati BK.ACS Nano. 2013 Apr 23;7(4):3264-75. doi: 10.1021/nn305958y. Epub 2013 Mar 20.PMID: 23464925 Free PMC article.

30. PMID: 22997228

Dual suppression of hemangiogenesis and lymphangiogenesis by splice-shifting morpholinos targeting vascular endothelial growth factor receptor 2 (KDR).

Uehara H, Cho Y, Simonis J, Cahoon J, Archer B, Luo L, Das SK, Singh N, Ambati J, Ambati BK.FASEB J. 2013 Jan;27(1):76-85. doi: 10.1096/fj.12-213835. Epub 2012 Sep 20.PMID: 22997228 Free PMC article.

31. PMID: 22467572

Nanoparticle-mediated delivery of shRNA.VEGF-a plasmids regresses corneal neovascularization.

Qazi Y, Stagg B, Singh N, Singh S, Zhang X, Luo L, Simonis J, Kompella UB, Ambati BK.Invest Ophthalmol Vis Sci. 2012 May 14;53(6):2837-44. doi: 10.1167/iovs.11-9139.PMID: 22467572 Free PMC article.

32. PMID: 22427553

Flt23k nanoparticles offer additive benefit in graft survival and anti-angiogenic effects when combined with triamcinolone.

Cho YK, Uehara H, Young JR, Tyagi P, Kompella UB, Zhang X, Luo L, Singh N, Archer B, Ambati BK.Invest Ophthalmol Vis Sci. 2012 Apr 30;53(4):2328-36. doi: 10.1167/iovs.11-8393.PMID: 22427553 Free PMC article.

33. PMID: 20005890

Anti-SPARC oligopeptide inhibits laser-induced CNV in mice.

Uehara H, Luo L, Simonis J, Singh N, Taylor EW, Ambati BK.Vision Res. 2010 Mar 31;50(7):674-9. doi: 10.1016/j.visres.2009.12.003. Epub 2009 Dec 22.PMID: 20005890 Free PMC article.

34. PMID: 19133260

Corneal stroma PDGF blockade and myofibroblast development.

Kaur H, Chaurasia SS, de Medeiros FW, Agrawal V, Salomao MQ, Singh N, Ambati BK, Wilson SE.Exp Eye Res. 2009 May;88(5):960-5. doi: 10.1016/j.exer.2008.12.006. Epub 2008 Dec 24.PMID: 19133260 Free PMC article.

35. PMID: 17460257

Nanoparticles sustain expression of Flt intraceptors in the cornea and inhibit injury-induced corneal angiogenesis.

Jani PD, Singh N, Jenkins C, Raghava S, Mo Y, Amin S, Kompella UB, Ambati BK.Invest Ophthalmol Vis Sci. 2007 May;48(5):2030-6. doi: 10.1167/iovs.06-0853.PMID: 17460257

36. PMID: 17198016

Unique homologous siRNA blocks hypoxia-induced VEGF upregulation in human corneal cells and inhibits and regresses murine corneal neovascularization.

Singh N, Higgins E, Amin S, Jani P, Richter E, Patel A, Kaur R, Wang J, Ambati J, Dong Z, Ambati BK.Cornea. 2007 Jan;26(1):65-72. doi: 10.1097/ICO.0b013e31802b4201.PMID: 17198016

37. PMID: 17151056

Soluble vascular endothelial growth factor receptor-1 contributes to the corneal antiangiogenic barrier.

Ambati BK, Patterson E, Jani P, Jenkins C, Higgins E, Singh N, Suthar T, Vira N, Smith K, Caldwell R.Br J Ophthalmol. 2007 Apr;91(4):505-8. doi: 10.1136/bjo.2006.107417. Epub 2006 Dec 6.PMID: 17151056 Free PMC article.

38. PMID: 17065489

Flt-1 intraceptor induces the unfolded protein response, apoptotic factors, and regression of murine injury-induced corneal neovascularization.

Singh N, Jani PD, Suthar T, Amin S, Ambati BK.Invest Ophthalmol Vis Sci. 2006 Nov;47(11):4787-93. doi: 10.1167/iovs.06-0419.PMID: 17065489

39. PMID: 17051153

Corneal avascularity is due to soluble VEGF receptor-1.

Ambati BK, Nozaki M, Singh N, Takeda A, Jani PD, Suthar T, Albuquerque RJ, Richter E, Sakurai E, Newcomb MT, Kleinman ME, Caldwell RB, Lin Q, Ogura Y, Orecchia A, Samuelson DA, Agnew DW, St Leger J, Green WR, Mahasreshti PJ, Curiel DT, Kwan D, Marsh H, Ikeda S, Leiper LJ, Collinson JM, Bogdanovich S, Khurana TS, Shibuya M, Baldwin ME, Ferrara N, Gerber HP, De Falco S, Witta J, Baffi JZ, Raisler BJ, Ambati J.Nature. 2006 Oct 26;443(7114):993-7. doi: 10.1038/nature05249. Epub 2006 Oct 18.PMID: 17051153 Free PMC article.

40. PMID: 15896317

Systemic soluble Tie2 expression inhibits and regresses corneal neovascularization.

Singh N, Macnamara E, Rashid S, Ambati J, Kontos CD, Higgins E, Ambati BK.Biochem Biophys Res Commun. 2005 Jun 24;332(1):194-9. doi: 10.1016/j.bbrc.2005.04.108.PMID: 15896317

41. PMID: 15851564

Flt-1 intraceptors inhibit hypoxia-induced VEGF expression in vitro and corneal neovascularization in vivo.

Singh N, Amin S, Richter E, Rashid S, Scoglietti V, Jani PD, Wang J, Kaur R, Ambati J, Dong Z, Ambati BK.Invest Ophthalmol Vis Sci. 2005 May;46(5):1647-52. doi: 10.1167/iovs.04-1172.PMID: 15851564

42. PMID: 14758337

Aquaporin-1 expression is decreased in human and mouse corneal endothelial dysfunction.

Macnamara E, Sams GW, Smith K, Ambati J, Singh N, Ambati BK.Mol Vis. 2004 Jan 26;10:51-6.PMID: 14758337 Free article.