Theses
Keshavanarayana, Pradeep (2019) Experimental and numerical investigations of stress fibre reorientation in biological cells. PhD Thesis.
Keshavanarayana, Pradeep (2014) Spatial Isogeometric Beam Elements. Master Thesis
Theses
Keshavanarayana, Pradeep (2019) Experimental and numerical investigations of stress fibre reorientation in biological cells. PhD Thesis.
Keshavanarayana, Pradeep (2014) Spatial Isogeometric Beam Elements. Master Thesis
Publications
Pradeep Keshavanarayana, Raul Aparicio-Yuste, Fabian Spill, Maria Jose Gomez-Benito, Effie E. Bastounis, Leveraging computational modeling to explore epithelial and endothelial cell monolayer mechanobiology. Trends in Cell Biology, 2025.
Margherita Botticelli, John Metzcar, Thomas Phillips, Susan Cox, Pradeep Keshavanarayana, and Fabian Spill. A hybrid computational model of cancer spheroid growth with ribose-induced collagen stiffening, bioRxiv, 2024.
P.Keshavanarayana, F. Spill, A mechanical modelling framework to study endothelial permeability, Biophysical Journal, 2024.
P.Keshavanarayana, M.Ruess, R.de Borst. On the monolithic and staggered solution of cell contractility and focal adhesion growth, International Journal for Numerical Methods in Biomedical Engineering, 2018.
P.Keshavanarayana, M.Ruess, R.de Borst. A feedback-loop extended stress fiber growth model with focal adhesion formation, International Journal of Solids and Structures, 2017.
Published Conference Proceedings
P.Keshavanarayana, S. Walker-Samuel, Patient-specific retinal geometry and vasculature distribution dictate the spatiotemporal progression of macular oedema. ARVO, 2025. (in press)
P.Keshavanarayana, Y.Javanmardi, E.Moeendarbary, F.Spill. Effect of physical and geometrical stimuli on microvascular dynamics. Biophysical Journal, 2023.
P.Keshavanarayana, M.Ruess. R. de Borst. A coupled stress-fiber focal-adhesion model for cell contractility, ECCM-ECFD, Glasgow, UK, 2018.
P.Keshavanarayana, R.de Borst, M. Ruess. A monolithic approach to cell contractility. Association for Computational Mechanics in Engineering, Cardiff, UK, 2016.
Conference Talks
Mechano-chemical regulation of endothelial permeability - an in-silico study, SMB, Seoul. 2024.
Role of endothelium in cancer extravasation - An in-silico study, ICCB, Vienna, 2023.
Mathematical model for the dynamics of the endothelium; British Applied Mathematics Colloquium, Bristol, 2023
A coupled stress-fibre focal-adhesion model for cell contractility; ECCM-ECFD, Glasgow, 2018.
A monolithic approach to cell contractility; UK-Applied Computational Mechanics Conference, Cardiff, 2016.
Analysis of the influence of substrate properties and focal adhesion formation on the stress fibre growth and reorientation in contractile cells; ICBME, Singapore, 2016.
Poster Presentations
Large strain curvature dependent reorganisation of endoplasmic reticulum, Mechanobiology in health and disease, Singapore, 2023 (presented by S. Rawal, TIFR, Hyderabad, India)
How mechanical forces affect permeability of endothelium, GRC Vascular Biology, Boston, USA, 2023
Endothelial cells playing a tug of war; EMBL, Barcelona, 2022
Mathematically modelling the dynamics of cell-cell junctions: Implications on the biology of spread of diseases; STEM for Britain finalist, UK Parliament, 2022
Numerical and experimental investigations of cell reorientation, University of Glasgow, 2018.
Numerical computation of stress fibre orientation, Cell Mech, Windermere UK, 2017.
Seminars
How gaps between cells determine health; Department of Mechanical Engineering, Indian Institute of Science, Bangalore, India, 2023.
Numerical modelling of single and collective cell contractility; University of Zaragoza, Spain, 2022.
From Cells to Space; INSPIRE internship camp, JNNCE, Shimoga, India, 2019.
Numerical model for stress fibre growth including focal adhesion formation; Department of Applied Mathematics, University of Glasgow, 2017.