🧬🌾 New publication 🧬🌾 

We’re proud to share our new review in Animals:
📄 Jitjumnong, J., Taweechaipaisankul, A., Lin, J. C., Wongchanla, S., Chuwatthanakhajorn, S., Lin, C. J., Khang, L. T. P., Linh, N. V., Sangsawad, P., Dinh‑Hung, N., Tang, P.C., & Moonmanee, T.  (2025). “An Overview of Advancements in Proteomic Approaches to Enhance Livestock Production and Aquaculture.” Animals 15(13):1946.

 🔗 Read the full article here: https://doi.org/10.3390/ani15131946

Highlights:
• 🔍 Proteomic Toolbox: Comprehensive review of key techniques—mass spectrometry, 2D‑gel electrophoresis, protein microarrays—for profiling protein complexity
• 🐮 Livestock Gains: Insights into how proteomics drives improvements in animal health, growth, reproduction, and disease resistance for more efficient, sustainable production
• 🐟 Aquaculture Innovations: Applications in fish health monitoring, selective breeding, and feed optimization to boost productivity under diverse environmental conditions
• ⚙️ Technical Challenges: Discussion of data complexity, lack of standardization, and interpretative hurdles that currently limit broader adoption
• 🔄 Future Directions: Multi‑omics integration, real‑time proteome monitoring, and environmental‑responsive protein function studies poised to overcome existing barriers

This review underlines proteomics’ pivotal role in tackling food‐security challenges and advancing sustainable agriculture.

🚀 Stay tuned for more cutting‐edge research from our lab!

🧬🌾 New publication 🧬🌾 

We’re proud to share our new review in Animals:
📄 Jitjumnong, J., Taweechaipaisankul, A., Lin, J. C., Wongchanla, S., Chuwatthanakhajorn, S., Lin, C. J., Khang, L. T. P., Linh, N. V., Sangsawad, P., Dinh‑Hung, N., Tang, P.C., & Moonmanee, T.  (2025). “An Overview of Advancements in Proteomic Approaches to Enhance Livestock Production and Aquaculture.” Animals 15(13):1946.

 🔗 Read the full article here: https://doi.org/10.3390/ani15131946

Highlights:
• 🔍 Proteomic Toolbox: Comprehensive review of key techniques—mass spectrometry, 2D‑gel electrophoresis, protein microarrays—for profiling protein complexity
• 🐮 Livestock Gains: Insights into how proteomics drives improvements in animal health, growth, reproduction, and disease resistance for more efficient, sustainable production
• 🐟 Aquaculture Innovations: Applications in fish health monitoring, selective breeding, and feed optimization to boost productivity under diverse environmental conditions
• ⚙️ Technical Challenges: Discussion of data complexity, lack of standardization, and interpretative hurdles that currently limit broader adoption
• 🔄 Future Directions: Multi‑omics integration, real‑time proteome monitoring, and environmental‑responsive protein function studies poised to overcome existing barriers

This review underlines proteomics’ pivotal role in tackling food‐security challenges and advancing sustainable agriculture.

🚀 Stay tuned for more cutting‐edge research from our lab!

🐟🌽 New publication 🐟🌽 

We’re delighted to share our latest paper in Fish & Shellfish Immunology:
📄 Van Doan, H., Wannavijit, S., Tayyamath, K., Quynh, T. T. D., Ninyamasiri, P., Linh, N. V., Wongmaneeprateep, S., Rodkhum, C., Seesuriyachan, P., Phimolsiripol, Y. & Hoseinifar, S. H. (2025).
“Effects of Fermented Corn Cob on Growth Performance, Digestive Enzyme, Immune Response, and Gene Expression of Nile Tilapia (Oreochromis niloticus) Raised in Biofloc System.” Fish & Shellfish Immunol. 110413.
🔗 Read the full article here: https://doi.org/10.1016/j.fsi.2025.110413

Highlights:
• ♻️ Sustainable Feed Additive: Fermented corn cob (FCC) repurposes agri‑byproduct for aquafeed
• 🐠 Growth Boost: Diets with 10–20 g kg⁻¹ FCC → significantly higher final weight, weight gain & SGR (P < 0.05)
• 🍴 Enhanced Digestion: FCC10 & FCC20 diets led to elevated protease, amylase & lipase activities
• 🛡️ Immune Uplift: Skin‑mucus and serum lysozyme, peroxidase & complement activities markedly increased in FCC‑fed fish
• 🧬 Gene Upregulation:

• Growth‑related: ghrelin, galanin, EF‑α, NPY‑α
  
  

• Immune‑related: il‑1β, MHC II‑α, TNF‑α, NFκB
  
  

• Antioxidant‑related: GPX, hsp70, nrf2
  • 🌱 Optimal Inclusion: 10–20 g kg⁻¹ FCC under biofloc conditions maximizes health & productivity
  
  

These findings support FCC as a sustainable functional feed additive to promote growth, digestive efficiency, innate immunity, and molecular health in tilapia aquaculture!

🚀 Stay tuned for more innovations from our lab!

🐛🧬 New Publication Alert! 🧬🐛
We’re excited to share our latest paper in Frontiers in Microbiology:
📄 Shahed, K., Islam, S. I., Sangsawad, P., Jung, W. K., Permpoonpattana, P., & Linh, N. V. (2025).  “Benchmarking Pangenome Dynamics and Horizontal Gene Transfer in Mycobacterium marinum Evolution.” Front. Microbiol. 16:1537826.
🔗 Read the full article here: http://dx.doi.org/10.3389/fmicb.2025.1537826

Highlights:
• 🔄 Driving Diversity: Horizontal gene transfer (HGT) as a catalyst for genetic variation and antibiotic resistance emergence
• 📊 Pangenome Analysis: Quantified gene gain, gene loss, and “openness” across M. marinum strains using Panstripe & GLM frameworks
• 🧬 Mobile Elements: Detected variable rates of gene flux linked to mobile genetic elements, underscoring ongoing genome plasticity
• 🔍 SNP Insights: Identified single nucleotide polymorphisms that may underlie strain‑specific traits like pathogenicity and drug resistance
• 🗂️ Annotation Benchmarking: Compared eggNOG vs. InterProScan GO annotations—each tool shines in different functional categories
• 🌐 Open Pangenome: Characterized M. marinum as highly open, reflecting continuous genetic exchange and adaptive potential

These findings illuminate the complex interplay between HGT, pangenome evolution, and antibiotic resistance in M. marinum, and introduce a robust analytical framework for future microbial genomics and vaccine‑target discovery!

🚀 Stay tuned for more cutting‑edge research from our lab!

🌸🦠 New Publication Alert! 🦠🌸
We’re thrilled to announce our latest paper in the International Journal of Microbiology:
📄 Yooklaen, Y., Srisawat, T., Khang, L. T. P., Dinh‑Hung, N., Sangsawad, P., Linh, N. V. & Permpoonpattana, P. (2025).  “Antibacterial Potential of Vatica diospyroides Flower Extracts: Targeting Diverse Pathogens in Aquaculture.” Int. J. Microbiol. 2025:7471536.
🔗 Read the full article here: https://doi.org/10.1155/ijm/7471536

Highlights:
• 🌿 Endemic Powerhouse: First in‑depth study of acetone extracts from V. diospyroides flowers
• 🧪 Broad‑Spectrum Activity: Inhibition zones of 6.33–17.66 mm against four aquaculture pathogens
• 🔍 Potent MICs:

• Vibrio parahaemolyticus: 62.5 µg/mL
  Bacillus subtilis & Escherichia coli: 250 µg/mL
  • ⚔️ MBC Range: 500 - 1000 µg/mL for more tolerant strains like Pseudomonas aeruginosa
  • ⏱️ Dose‑ & Time‑Dependent Killing: Flow cytometry shows higher concentrations and longer exposure ramp up bacterial death
  • 🔬 Visual Proof: SEM images reveal clear structural damage in both Gram‑positive & Gram‑negative cells
  
  

These findings highlight V. diospyroides flower extracts as a promising natural antibacterial agent for more sustainable aquaculture health management!

🚀 Stay tuned for more breakthroughs from our lab!

🐔🥚 New Publication Alert! 🥚🐔

We’re excited to share our latest paper in Scientific Reports:
📄 Dangsawat, O., Rattanawut, J., Srisawat, T., Sowanpreecha, R., Khang, L. T. P., Srinual, O., Dinh-Hung, N., Do-Hyung, K., Husna, N. N., Dwinanti, S. H., Linh, N. V. & Permpoonpattana, P. (2025). “Bacillus aryabhattai CKNJh11 as a promising probiotic improves growth performance and egg quality in laying hens.” Scientific Reports 15:13659.
🔗 Read the full article here: https://doi.org/10.1038/s41598-025-97553-8

Highlights:
• 🌱 Diverse Isolation: 11 Bacillus strains from mud crab, blue crab, banana shrimp guts, pond sludge, hot-spring soil & chicken feces
• 💪 Strong Spore Formers: CKNJh11 showed 80.3% spore efficiency (others up to 82%)
• 🛡️ Safety & Tolerance: Sensitive to key antibiotics, non-hemolytic, resistant to gastric juice & bile salts
• 🐓 Probiotic Power: 6-week feeding trial → significant ↑ body weight gain & eggshell weight (p < 0.05)
• 🥇 Star Strain: 16S rRNA confirmed CKNJh11 as B. aryabhattai—a top candidate for supplementing layer diets

These findings pave the way for next-gen probiotic supplements to boost hen health and egg quality!

🚀 Stay tuned for more breakthroughs from our lab!

We are pleased to announce the publication of our latest research article:
📄 Islam, S. I., Shahed, K., Ahamed, M. I., Khang, L. T. P., Jung, W.-K., Sangsawad, P., Dinh-Hung, N., Permpoonpattana, P., & Linh, N. V. (2025). Pathogenomic Insights into Piscirickettsia salmonis with a Focus on Virulence Factors, Single-Nucleotide Polymorphism Identification, and Resistance Dynamics. Animals, 15(8), 1176.
🔗 Read the full article here: https://doi.org/10.3390/ani15081176

🌊 Piscirickettsia salmonis causes devastating losses in salmon aquaculture. In this study, we:
• Mapped an open pan-genome (14,564 genes) and a core genome (1,257 genes)
• Identified 11 virulence genes across 5 functional groups
• Discovered unique SNPs in gyrA, dnaK, rpoB & ftsZ for rapid strain typing
• Detected AMR genes in LF strains, highlighting antibiotic-resistance evolution

🔬 These insights pave the way for better diagnostics, targeted treatments, and smarter management of piscirickettsiosis.

🚀 Stay tuned for more breakthroughs from our lab!

On March 27th, the Laboratory of Aquatic Biotechnology - Department of Animal and Aquatic Sciences successfully organized an exciting internship activity for 1st and 2nd-year students at Chiang Mai University! This event provided a valuable hands-on learning experience in aquatic research and biotechnology. 

More details at: Internship Activity at Chiang Mai University  27.03.2025 

We are pleased to announce the publication of our latest review article:

📄 Khang, L. T. P., Dinh‐Hung, N., Islam, S. I., Dwinanti, S. H., Mwamburi, S. M., Permpoonpattana, P., & Linh, N. V. (2025). A Review of In Silico Approaches for Discovering Natural Viral Protein Inhibitors in Aquaculture Disease Control. Journal of Fish Diseases, e14120. 

🔗 Read the full article here: https://onlinelibrary.wiley.com/doi/epdf/10.1111/jfd.14120

🌍 Viral diseases remain a major challenge in global aquaculture, leading to economic losses and threatening food security. Our review explores the role of computational (in silico) techniques in identifying natural compounds with antiviral properties. We discuss key approaches such as molecular docking, virtual screening, ADMET profiling, and molecular dynamics simulations, which streamline drug discovery and reduce reliance on wet-lab experiments. Additionally, we highlight the potential of artificial intelligence and multi-omics technologies in advancing antiviral research.

This work underscores the importance of integrating computational and traditional screening methods for effective disease management in aquaculture.

🔬 Stay tuned for more exciting research from our lab! 🚀