PhD in Breast Cancer at Ghent University (Belgium)
PhD in Breast Cancer at Ghent University (Belgium)
looking for a talented PhD candidate to join our teams at Ghent University (Belgium) for a highly interdisciplinary project that bridges chemistry, biology and medicine.
This open position focusses on the development of nanocrystals for oncological applications, with a special focus on breast cancer.
Do you want to contribute to cutting-edge translational research in the field of medical imaging and oncology? Do you want to work in a collaborative environment where many specialties meet at a world-renowned institution? Do you feel as if you will weep with joy when you hear the words “chemistry”, “ in vivo” and “medical imaging”?
Then you just may be the person we are looking for! 😉
📚 Requirements: Master’s degree in Chemistry, Pharmaceutical sciences, Nanosciences, Biochemistry, Biomedical sciences, Biomedical engineering, or equivalent.
Application deadline: 28/02/2025
How to apply Send your application or any questions concerning this vacancy to: ➔ Dr. Loren Deblock, loren.deblock@ugent.be
➔ Prof. Dr. Christian Vanhove, christian.vanhove@ugent.be
➔ Prof. Dr. Isabel Van Driessche, isabel.vandriessche@ugent.be
IMPORTANT: Please put these three email addresses in ALL your communications. Applications should include: - Your CV - A personal motivation letter of maximum 1 page - A copy of your diploma (if already in your possession) - A transcript of courses taken, their grades within bachelor and master studies, and the languages the courses were taught in. - Contact information of minimum two reference persons After screening, selected candidates will be invited for an online interview as a first contact in a multi-stage selection process. Your complete online application must be submitted no later than 28 February 2025. We do not accept late applications
Contact via website: The Liu Lab
contact Prof. M. Carolina Florian in Bellvitge Biomedical Research Institute - IDIBELL. P-CMR[C] Program for Clinical Translation of Regenerative Medicine in Catalonia
RAO lab at John Hopkins. https://raolab.jhmi.edu/
Are you interested in organoid biology and iPS technology? We are applying these, and other cell physiology and membrane transport approaches to study neurodegenerative disorders, keratinocyte biology and mammary biology. Our ideal candidate will have experience in one of the above areas, and skills in molecular/cell biology.
The project focuses on the development of nucleic acid amplification methods and electrokinetic lateral flow technology for rapid and ultrasensitive
#diagnostics (more info: https://lnkd.in/dNfieZ2j)
#OpenDays on Zoom on Wednesday 18th December 2024 at 11 am and Tuesday 14th January 2025 at 3 pm
(register: https://lnkd.in/dCGrW3UX)
Application
#Deadline: 26th January 2025
Project Start Date: Oct 2025
Contact me if you're interested in applying!
Two Ph.D. Positions in Cancer Research in soucek lab
Institute of Biophysics Akademie věd České republiky St. Anne's University Hospital Brno MU Faculty of Science to study Tetraspanins in Prostate Cancer and the Role of Trop2 in Metastasis.
Deadline: March 31, 2025
Send CV & motivation letter to ksoucek@ibp.cz
Dr. El-Demerdash's Research Group, School of Chemistry, Pharmacy, and Pharmacology, University of East Anglia, UK
Bioinspired Synthesis of Bioactive Marine Natural Products - Small Molecule Synthesis
We are seeking a highly motivated and accomplished researcher with a proven track record in Synthetic Organic and Medicinal Chemistry to apply for the prestigious International Newton Fellowship in our research group. The successful candidate will contribute to cutting-edge research focused on marine-derived bioactive molecules, with particular emphasis on innovative therapeutic applications targeting potent anticancer and antiviral agents.
Lead independent synthetic and medicinal chemistry research, driving the project from design to implementation.
Conduct and apply advanced computational chemistry studies, including molecular docking and molecular dynamics simulations for fragment-based drug discovery and pharmacophore virtual screening.
Collaborate within a multidisciplinary research environment, contributing to publications and conference presentations.
PhD in Synthetic Organic Chemistry, Medicinal Chemistry, or a related field.
Strong publication record in high-impact journals.
Expertise in complex organic synthesis, drug design, and bioactive compound development.
Proven experience in computational chemistry tools such as AutoDock, Schrödinger, or similar software.
Ability to work independently while contributing to a collaborative research environment.
Strong and hands-on experience in synthetic organic and medicinal chemistry.
Familiarity with structure-activity relationship (SAR) studies.
Knowledge of modern analytical techniques (NMR, MS, HPLC).
Interested candidates are encouraged to contact Dr. El-Demerdash directly with a cover letter, CV, and a summary of research experience and future aspirations. Please highlight how your expertise aligns with our group's research interests in synthetic organic, medicinal natural products chemistries, and computational drug discovery.
Deadline for receiving CVs:
1st January 2025 via A.Eldemerdash@uea.ac.uk
We are looking for a curious and driven candidate with interest in
* Systems immunology
* Cellular and molecular immunology
* Sex differences in immunity
🧪 The research
Immune mediated diseases have marked sex bias. As a Systems Immunology postdoc in our group, you will investigate how biological sex impacts human immune responses.
🔬 The project
Your project will entail investigating molecular mechanisms of sex hormone regulation of human immune function. This will entail using CRISPR systems for gain and loss of function studies in primary human immune cells, coupled with transcriptomic (bulk & scRNA-seq), epigenomic (CUT&RUNseq), and immunophenotypic profiling (cytometry).
🥼 The profile of the candidate
The candidate must hold a PhD in Life Sciences (with PhD acquired within three years of the application deadline) or show proof of imminent PhD degree completion by the agreed start date. The candidate must have strong interest and experience with molecular biology and immunology. Experience in molecular immunology (genetic manipulation including transfection/electroporation, DNA/RNA extraction, PCR, CRISPR, sequencing) and in human immunology wet lab methods (handling blood, tissue culture, flow cytometry) are a benefit. Having computational biology expertise (or willingness to learn such methods) is also an advantage. The candidate is expected to work collaboratively with our multi-cultural team, and should be proficient in oral and written communication in English.
🏘️ The lab and environment
The postdoc position is placed at the Systems Immunology Lab at the Department of Laboratory Medicine within the Faculty of Medicine at Lund University, Lund (Sweden). More info of our group can be found at https://lnkd.in/evhemkpb. The research team is led by Assistant Prof. Camila Consiglio, and includes a three MSc, two PhD students and one postdoc. As a workplace, we are committed to creating a respectful, supportive, and stimulating learning environment.
Interested? Apply by January 6th 2025
✉️ Email camila.consiglio[at]med.lu.se (email subject including V2024/2563) with:
A) 1-page cover letter with brief description of how your expertise fits the call, and why you are interested in joining our group;
B) 2-page CV, including contact details for 2-3 references;
C) Copy of your diploma (or indication of PhD defense before agreed start date).
The Tessier lab has three open postdoc positions related to antibody engineering, bispecific antibodies (brain shuttles), delivery of bispecific antibodies to the central nervous system (CNS), and evaluation of pharmacokinetics, biodistribution, and efficacy of CNS-targeted bispecific antibodies that deliver payloads ranging from gene silencing agents (ASOs and siRNA) to small proteins (cytokines) and IgGs (agonists and antagonists). The projects build on our recent report of brain shuttles that target transferrin receptor (TfR-1) and CD98hc and are efficiently delivered to the brain parenchyma (https://lnkd.in/gyXfhuzN). Our TfR-1 and CD98hc shuttles have unique advantages – including fast and maximal brain uptake for TfR-1 shuttles and extended brain retention of CD98hc shuttles – and are the basis for the open projects. The field of brain shuttling using bispecific antibodies is rapidly growing due to their potential for improving CNS delivery of biologics that otherwise poorly penetrate the blood-brain barrier (BBB), and these projects would position postdocs for exciting future career opportunities in industry, academia, and government agencies.
In Project #1, we seek candidates interested in antibody engineering using phage and yeast-surface display for generating and affinity maturing antibodies specific for BBB and CNS targets, combining them into bispecific antibodies, and evaluating them in vitro and in vivo. This project will provide opportunities to develop expertise in generating antibody libraries, performing phage and yeast surface display selections, conducting deep sequencing, bioinformatics and machine learning analysis, protein production and purification, and characterization of antibody affinity, specificity, and other biophysical properties.
In Projects #2 and #3, we seek candidates interested in the in vivo evaluation of antibody brain shuttles, including their pharmacokinetics, organ and cellular biodistribution, and efficacy in preclinical models. These projects will involve delivering gene silencing agents (ASOs and siRNAs) in Project #2 and proteins (cytokines and IgGs) in Project #3 for applications in neurodegenerative diseases. This research will provide opportunities to develop expertise in protein production and purification, pharmacokinetics analysis using radiotracing, biodistribution in brain and spinal cord using imaging methods, and analysis of efficacy in different preclinical models of neurodegenerative diseases.
Interested candidates should email Dr. Tessier (ptessier@umich.edu) and provide a CV and the names of three references with email addresses.
Zhi Yang Lab is seeking for motivated PhD or Master’s (by research) student to join my research group in Fall 2025 at the University of Hawaiʻi at Mānoa, Honolulu, USA. Our research focuses on food chemistry and ingredient functionality, including developing novel fat mimics and valorizing tropical agricultural and food waste. This position offers a fully funded assistantship of approximately $25,000–$26,000 per year for 3 years (PhD) or 2 years (Masters), with the tuition fee waived. For detailed application requirements, please check https://lnkd.in/gqAVH5sx
https://lnkd.in/gXj99n2k.
Interested candidates should email their CV, academic transcript, English test scores (e.g., TOEFL, IELTS), and any publications to zhiy@hawaii.edu.
A) Apply for a Postdoctoral fellowship (2 years) funded by Kempe foundations (for details check our lab page) [investigating adaptive mechanisms in human gut associated microbes]
b) Apply for a postdoc position through NORPOD (Shared with Najumuddin lab, Helsinki) - Genetic and adaptive dynamics of microbiome in colorectal cancer: How do microbes adapt to the hostile tumour microenvironment? (ADAPT-MIC) (https://lnkd.in/d-4rhwfd)
c) Apply for a postdoc position with us through the Scilife PULSE program (https://lnkd.in/dQyVMhWs)
d) If none of the above fits well, write to us with your cv!
The Lab. Alzheimer’s Neuroimaging & Epidemiology at the IRCCS Fatebenefratelli in Brescia is seeking a researcher to work on the project “Novel neuroradiological workflow for the assisted DIAgnosis and management of DEMentia with Artificial intelligence - DIADEMA” under the supervision of Dr. Michela Pievani. The project is funded by the PNRR call (PNRR-MCNT2-2023-12378268) and the candidate will work on the development of pipeline for neuroimaging data analysis, the collection and analysis of neuroimaging data, and scientific dissemination. The position is available for one year with possibility of extension.
Key Requirements
- A master’s degree and/or a PhD in bioengineering, mathematics, physics, neuroscience, or related field
- Knowledge of basic toolboxes for neuroimaging analysis
- Programming skills (e.g., bash, Matlab, Python, Rstudio)
- Good knowledge of English language
How to apply:
LinkeIn: https://lnkd.in/d-NY8yCT, https://lnkd.in/dxXxSHZj or send the CV to risorseumane.irccs@fatebenefratelli.eu, indicating in the subject: “Application PNRR-MCNT2-2023-12378268