DAMST: Domain-Adaptive Medical Slice Transformer for Multi-Center Breast MRI Classification
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We developed a robust AI framework (DAMST) for breast cancer detection from MRI scans across multiple hospitals. DAMST combines DINOv2-based image features, a Medical Slice Transformer (MST), and adversarial domain adaptation to learn discriminative features while reducing the influence of scanner- and hospital-specific variations.
Key achievements include:
Developing a hybrid framework to extract discriminative features from volumetric breast MRI data;
Introducing gradient reversal and prototype-based learning to reduce domain bias and align class representations across medical centres;
Evaluating the framework on five independent multi-centre breast MRI datasets, demonstrating improved classification accuracy and generalisation compared with existing methods.
This approach supports more reliable breast cancer detection across diverse clinical environments, advancing the development of generalisable AI systems for real-world medical imaging applications.
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