*As first or †corresponding author (Members of the ABDE Lab are underlined and boldfaced)
2025
37. Development of Radiation Mask Layer (RML) for 3D-in vitro Radiation Sensitivity Test in Head and Neck Squamous Cell Carcinoma (HNSCC)
In-preparation (Joint research withthe Samsung Medical Center and Gachon university)
36. Long-Term Plate Preservation for Efficient Drug Screening of Patient-Derived Ovarian Cancer Organoids and Clinical Validation of Anticancer Drug Sensitivity Assays
In-preparation (Joint research with the Samsung Medical Center and Gachon university)
35. Development of a Cell-subculture Bell Device (C-Bell) Using Low-Cost RGB Color Sensors
*In-Seong Koo, *Sung Jae Chang, Na Min Park, Sang-Yun Lee†, Dong Woo Lee†
Under review (Joint research with Gachon university)
34. 3D Airway Organoid Model for Investigating Particulate Matter-Induced Epithelial-Mesenchymal Transition and Inflammatory Response
*Eunyoung Lee, *Sang-Yun Lee, Yu-Jeong Seong, Jeong Uk Lim, Jae-Young Jeong, Yongki Hwang, Hyobin Won, Seok Whan Moon, Young Du Kim, Kyung Soo Kim, Mi Hyoung Moon, Seung Keun Yoon, Yeoun Eun Sung, Meejeong Kim, and Dong Woo Lee†
Under review (Joint research with the Catholic University of Korea Seoul ST.MARY`S Hospital and Gachon university)
33. An Esophageal Cancer Organoid-Based Model for Predicting Pathological Response and Recurrence Risk Following Neoadjuvant Chemoradiotherapy
*Eunji Jeong, *Jong Yun Baek, *Sang-Yun Lee, Yongmun Choi, Bosung Ku, Man Ki Chung, Dong Woo Lee†, and Dongryul Oh†
Under review (Joint research with the Samsung Medical Center and Gachon university)
32. Using Patient-derived Organoid Growth Rates as a Phenotypic Marker to Predict Adjuvant Therapy Outcomes in Ovarian Cancer Patients
*Sung Hun Ju, *Sang-Yun Lee, *Joseph J Noh, Yu-Jeong Seong, Bosung Ku, Jun Hyeong Seo, Jung-Joo Choi, Min Jeong Kim, Filippo Piccinini, Yong-Jun Kwon, Jeong Won Lee†, and Dong Woo Lee†
Submitted to journal (Joint research with the Samsung Medical Center and Gachon university)
31. Development and Clinical Validation of an Automated Radiation Modulator (ARM) for High-Throughput Irradiation of Variable Doses to 3D Head and Neck Squamous Cell Carcinoma (HNSCC) Patient-Derived Organoids
*Jin-Young Lee, *Eunji Jeong, *Sang-Yun Lee, Yu-Jeong Seong, Heejong Song, Bosung Ku, Sanghyo Kim, Dongryul Oh, Man Ki Chung†, Dong Woo Lee†
Under review (Joint research with the Samsung Medical Center and Gachon university)
30. Growth Rate-Incorporating Multivariable (GR-IM) Prediction Model for Adjuvant Therapy and Clinical Prognoses in Breast Cancer Patients
*Ji-Jung Jung, *Ga-Yeon Kim, Kyung-Hyun Park, Bosung Ku, Yong-Mun Choi, Seung-Yeon Ryu, Sang-Yun Lee†, Won-Shik Han†, and Dong Woo Lee†
Under review (Joint research with the Seoul National University Hospital and Gachon university)
29. Prognostic Model for Patients with Oral Cavity Cancer Using a Novel Multi-Parameter Index Including Radiation Response of Patient-Derived Tumoroids
*Eunji Jeong, *Yongmun Choi, *Dong Woo Lee, Sang-Yun Lee, In Jae Bang, Bosung Ku, Jae Gyun Lim, Sang Youl Jeon, Patrick Ha, Young Wook Jun, Ivan H. El-Sayed†, Dongryul Oh†, and Man Ki Chung†
Under review (Joint research with the Samsung Medical Center and Gachon university)
28. Comparison of Depth of Anesthesia Models based on Bispectral and Cortical Activity Index
*Hyun Tae Jeong, Seok-Jin Lee, Seung Kyun Hong, Hyun Park, Jinyoung Lee, Sang-Yun Lee, Dong Woo Lee†, and Tae-Yun Sung†
Under review(Joint research with the Gachon university and Konyang university)
27. Applications and Research Trends in Organoid-Based Infectious Disease Models
24. Lung Cancer Organoid-based Drug Evaluation Models and New Drug Development Application Trends
*Eunyoung Lee, *Sang-Yun Lee, *Yu-Jeong Seong, Bosung Ku, Hyeong Jun Cho, Kyuhwan Kim, Yongki Hwang, Jeong Uk Lim, Chan Kwon Park, Joon Young Choi, Chang Dong Yeo, Sung Won Kim, Seung Joon Kim†, and Dong Woo Lee†
Translational Lung Cancer Research. DOI: 10.21037/tlcr-24-603
23. Histo-Pillar Strip for Optimal Histogel Block Construction and Biomarker Analysis in 3D-Lung Cancer Patient-Derived Organoids
*Sang-Yun Lee, *Eunyoung Lee, Ji-O Ryu, Kyuhwan Kim, Yongki Hwang, Bosung Ku, Seok Whan Moon, Mi Hyoung Moon, Kyung Soo Kim, Kwanyong Hyun, Jeong Uk Lim, Chan Kwon Park, Sung Won Kim, Chang Dong Yeo, and Dong Woo Lee† and Seung Joon Kim†
22. U-shape pillar strip for 3D cell-lumped organoid model (3D-COM) mimicking lung cancer hypoxia conditions in high throughput screening (HTS)
*Sang-Yun Lee, *Eunyoung Lee, *Jeong Uk Lim, Bosung Ku, Yu-Jeong Seong, Ji-O Ryu, Hyeong Jun Cho, Kyuhwan Kim, Yongki Hwang, Seok Whan Moon, Mi Hyoung Moon, Kyung Soo Kim, Kwanyong Hyun, Tae-Jung Kim, Yeoun Eun Sung, Joon Young Choi, Chan Kwon Park, Sung Won Kim, Chang Dong Yeo†, Seung Joon Kim†, and Dong Woo Lee†
21. A Feasibility Test of the Disposable Drug Daughter Plate Combined with 384-Pillar Plate for Patient-Derived Organoid-Based High Throughput Screening
*Kyunghyun Park, *Ji-O Ryu, *Gayeon Kim, Bosung Ku, Yongmun Choi, Ji-Youn Lee, Sang-Yun Lee† and Dong Woo Lee†
19. Cancer Organoid based Diagnosis Reactivity Prediction (CODRP) Index-based Anticancer Drug Sensitivity Test in ALK-Rearrangement Positive Non-Small Cell Lung Cancer (NSCLC)
*Sang-Yun Lee, *Hyeong Jun Cho, *Jimin Choi, Bosung Ku, Seok Whan Moon, Mi Hyoung Moon, Kyung Soo Kim, Kwanyong Hyun, Tae-Jung Kim, Yeoun Eun Sung, Yongki Hwang, Eunyoung Lee, Dong Hyuck Ahn, Joon Young Choi, Jeong Uk Lim, Chan Kwon Park, Seung Joon Kim, Sang-Hyun Lee†, Chang Dong Yeo† and Dong Woo Lee†
Journal of Experimental & Clinical Cancer Research. DOI: 10.1186/s13046-023-02899-4.
(Nov/2023, ISSN: 0003-2700, IF: 11.3), *Featured in BRIC “HANBITSA”
17. Current literature review on the tumor immune micro-environment, its heterogeneity and future perspectives in treatment of advanced non-small cell lung cancer
*Jeong Uk Lim, Eunyoung Lee, Sang-Yun Lee, Hyeong Jun Cho, Dong Hyuck Ahn, Yongki Hwang, Joon Young Choi, Chang Dong Yeo†, Chan Kwon Park, and Seung Joon Kim
Translational Lung Cancer Research. DOI: 10.21037/tlcr-22-633.Epub.
12. Cell-Proliferation-Receptor enhanced 3D-High Throughput Screening (CPRE 3D-HTS) Model for Optimized Drug Efficacy Evaluation in Breast Cancer Cells
*Sang-Yun Lee, *Hyun Ju Hwang, Bosung Ku, and Dong Woo Lee†