Aaron Halvorsen - Aspiring MSL

Publications

The Perineuronal Net Protein Brevican Acts in Nucleus Accumbens Parvalbumin-Expressing Interneurons of Adult Mice to Regulate Excitatory Synaptic Inputs and Motivated BehaviorsExperience-dependent functional adaptation of nucleus accumbens (NAc) circuitry underlies the development and expression of reward-motivated behaviors…

The impact of deep space radiation on cognitive performance: From biological sex to biomarkers to countermeasuresSpace radiation affects memory in male and not in female mice, and it is dependent on the innate immune system response.

Changes in hemodynamic response to faces, scenes, and objects in a visual statistical learning task: An fMRI analysisLearning causes changes in brain activity and neural connections. Statistical learning is an implicit learning process that involves extracting regularities from the environment and finding patterns in stimuli based on their transitional probabilities. The following study describes an attempt to elucidate temporal changes in hemodynamic activity for three category-specific brain areas using functional magnetic resonance imaging (fMRI). Blood oxygen-level dependent signal (BOLD) responses were collected while subjects viewed faces, scenes, and objects with high and low transitional probabilities in an fMRI scanner. We expected brain activity to show a temporal shift in timing of activation when comparing BOLD signal responses before and after visual statistical learning. Instead, a general, yet insignificant, trend in the magnitude of activation was found. Although these findings suggest category-specific brain areas may undergo magnitude changes in activation for item-specific stimuli in response to visual statistical learning, further confirmatory analyses and comparisons to behavioral data are needed.

Hazlett M, Hall V, Patel E, Halvorsen A, Calakos N, West AE. The Perineuronal net protein brevican acts in nucleus accumbens parvalbumin-expressing interneurons of adult mice to regulate excitatory synaptic inputs and motivated behaviors. Biol Psychiatry. 2024 Feb 10; 10:S0006-3223(24)00080-5. doi: 10.1016/j.biopsych.2024.02.003. Epub ahead of print. PMID: 38346480.
Krukowski K, Grue K, Becker M, Elizarraras E, Frias ES, Halvorsen A, Koenig-Zanoff M, Frattini V, Nimmagadda H, Feng X, Jones T, Nelson G, Ferguson AR, Rosi S. The impact of deep space radiation on cognitive performance: From biological sex to biomarkers to countermeasures. Sci Adv. 2021 Oct 15;7(42):eabg6702. doi: 10.1126/sciadv.abg6702. Epub 2021 Oct 15. PMID: 34652936; PMCID: PMC8519563.
Halvorsen, A. (2019). Changes in hemodynamic response to faces, scenes, and objects in a visual statistical learning task: An fMRI analysis. University of Nebraska-Lincoln Digital Commons. Undergraduate Honors Thesis.

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