SLIDE CONFERENCE

Brief History

The patient was a 50-year-old nulliparous woman. Several months prior to surgery, she presented to the clinic with dysmenorrhea as her chief complaint. A colposcopy revealed a thumb-sized mass within the cervical canal. A pelvic MRI confirmed a tumor originating primarily from the uterine body and protruding into the vaginal cavity. An endometrial biopsy was performed for further evaluation. What is your DIAGNOSIS ?

Brief History

A 35-year-old woman was scheduled to undergo hysterectomy at an outside hospital for uterine leiomyoma. However, she presented to the emergency department with lower abdominal pain that developed during medical treatment for abnormal uterine bleeding. MRI revealed an 8.7 × 5.6 cm mass within the endometrial cavity, and a biopsy was performed. She subsequently underwent total hysterectomy and bilateral salpingo-oophorectomy at our institution. The submitted slides represent a representative section of the resected tumor. 

Brief History

This 45-year-old woman (G3P2AA1) with no significant past medical history was found to have a right ovarian tumor measuring 5 cm during a routine health check-up in 2005. The lesion was initially suspected to be a teratoma, and she was followed at an outside hospital. On imaging follow-up in June 2025, the tumor had increased in size to 12 cm, raising suspicion for malignancy. The patient subsequently sought a second opinion, and debulking surgery was performed. The right ovarian tumor was submitted for intraoperative (frozen section) examination.

Laboratory data: CA-125: 127.9 U/mL, CEA: 1.76 ng/mL, CA-199: 6.08 U/mL