GlycoNeuro Satellite Meeting
Date and Time: Friday, Sept 1, 2023, 6-7:30 pm - Saturday, Sept 2, 2023, 9 am - 6 pm.
Venue: B1C Auditorium, Institute of Biomedical Sciences, Academia Sinica, Taipei, Taiwan
Registration required, free for local and registered participants of Glyco26.
Organized by
Kay-Hooi Khoo, Chi-Kuang Yao and Neuroscience Program of Academia Sinica (NPAS)
Sept 1, 2023
From 17:20, Social Mixing (light snack and drinks provided)
18:00 – 19:30 Opening Session, introduced by Kay-Hooi Khoo (IBC, Academia Sinica, Taiwan)
18:00 Sandro Sonnino (U Milan, Italy),
Opening and Introductory Lecture: "The glycans of glycoconjugates in neuronal processes"
18:30 Rita Gerardy-Schahn (Hannover Medical School, Germany)
Glyco-Neuroscience Perspective Lecture: "Chemistry and biology of polysialic acid with focus on neurobiological aspects"
19:00 Introducing Speakers and local NPAS scientists
Sept 2, 2023
09:00 - 10:40 Scientific Session I, Invited Talks (4x 20+3 min), chaired by Chih-Cheng Chen (IBMS, Academia Sinica, Taiwan)
09:00 Matt Macauley (U Alberta, Canada), "Studying the in vivo role of CD33 isoforms in an Alzheimer's disease mouse model"
09:25 Kenji Uchimura (U Lille, France), "Sulfated glycans that regulate microglial function"
09:50 Jian-Jing Siew (IBMS, Taiwan), "Microglial galectin-3 aggravates tauopathy"
10:15 Takashi Angata (IBC, Academia Sinica, Taiwan), "Deciphering the molecular basis and functional roles of glycan-based immune checkpoints in neurodegenerative diseases"
10:40 - 11:00 Coffee Break
11:00 – 11:30 Short Talks from Posters (2x 12+2 min), chaired by Takashi Angata (Academia Sinica, Taiwan)
11:00 Hua-Chien Chang (IBC, Academia Sinica, Taiwan) "Identification and mapping of novel sulfated glycotopes expressed on mouse brains and isolated neurons by mass spectrometry-based sulfoglycomic analysis"
11:15 Yan-Hua Lee (IBMS, Academia Sinica, Taiwan) "Siglecs Alteration in Huntington’s Disease"
11:30 - 12:10 Keynote Lecture I, chaired by Yijuang Chern (IBMS, Academia Sinica, Taiwan)
· Herbert Hildebrandt (Hannover Medical School), "Modulation of microglia and macrophage activity by polysialic acid and its Siglec receptors"
12:10 – 13:20 Lunch Break and Poster viewing
13:20 - 14:00 Keynote Lecture II, chaired by Chi-Hon Lee (ICOB, Academia Sinica, Taiwan)
· Alexey Pshezhetsky (U Montreal, Canada), " Mucopolysaccharidosis and Epileptic encephalopathy, the two extremes of aberrant heparan sulfate regulation in the CNS"
14:00 - 15:40 Scientific Session II, Invited Talks (4x 20+3 min), chaired by Kay-Hooi Khoo (IBC, Academia Sinica, Taiwan)
14:00 Sophia Shi (Stanford U, USA) "Cerebrovascular glycocalyx degeneration in aging and neurodegenerative disease"
14:25 Yun-Ru (Ruby) Chen (GRC, Academia Sinica, Taiwan), "Investigation of abnormal glycosylation in Alzheimer's disease"
14:50 Cheng-Ting Chien (IMB, Academia Sinica, Taiwan), "Glycosylation in dendrite development and degeneration"
15:15 Chihiro Sato (Nagoya U, Japan), "Comparative study of the polysialic acid synthesized by ST8SIA2 and ST8SIA4"
15:40 - 16:00 Coffee Break
16:00 - 16:45 Short Talks from Posters (3x 12+2 min), chaired by Chi-Kuang Yao (IBC, Academia Sinica, Taiwan)
16:00 Masaya Hane (Nagoya U, Japan) "A new analytical method measuring the interaction between polysialic acid and dopamine-lead compounds"
16:15 Keisuke Komatsuya (Tokyo Metropolitan Institute of Medical Science, Japan) “Signal Transduction of GPI-anchored NB-3 in Ganglioside GD1b Lipid Rafts of Cerebellar Granule Cells”
16:30 Giulia Lunghi (U Milan, Italy) “The neuroprotective role of the oligosaccharide of ganglioside GM1 in Parkinson’s disease”
16:45 - 17:45 Poster Session
17:45 Closing Discussion