Stem cells and their vesicles, directed against autoimmune disease
Lotfy Lab investigates mesenchymal stem/stromal cells (MSCs) and MSC-derived extracellular vesicles, exosomes and EVs, as potential therapies for autoimmune and degenerative diseases, including Type 1 Diabetes. We probe the mechanisms of MSC-mediated immunomodulation, tissue repair, and cell-free therapeutic strategies.