Collaborations & Connections
Tissue Regeneration through Exosome Engineering
Tissue Regeneration through Exosome Engineering
Our precision porous scaffolds promote exquisite healing through the exclusive intermingling of specific T cells and M1-macrophage phenotypes that generate exosomes with unique miRNA and protein content capable of re-programming cells into desired tissue cells (trans-differentiation). NIH - 5R01GM128991-02.
Our precision porous scaffolds promote exquisite healing through the exclusive intermingling of specific T cells and M1-macrophage phenotypes that generate exosomes with unique miRNA and protein content capable of re-programming cells into desired tissue cells (trans-differentiation). NIH - 5R01GM128991-02.
West Coast Exosome Consortium
West Coast Exosome Consortium
The WestCo Exosortium is a growing collective founded to connect extracellular vesicle researchers. Our primary goals are to establish productive research collaborations, obtain collaborative funding, and share expertise, data, and methods between member labs.
Founder: Dr. Billie Hwang
Functional Amyloid Formation in Bacteria
Functional Amyloid Formation in Bacteria
Biofilm are microorganisms entrapped in a 3D extracellular matrix (ECM) of their own making; the ECM comprises extracellular polysaccharides, DNA, and proteins, the latter mostly in the form of amyloid fibrils. This project analyses the mechanism of amyloid formation in both Gram-positive and Gram-negative bacteria, introduces two different synthetic peptide design approaches to inhibit amyloid formation, and translates the results to clinically relevant models.
Biofilm are microorganisms entrapped in a 3D extracellular matrix (ECM) of their own making; the ECM comprises extracellular polysaccharides, DNA, and proteins, the latter mostly in the form of amyloid fibrils. This project analyses the mechanism of amyloid formation in both Gram-positive and Gram-negative bacteria, introduces two different synthetic peptide design approaches to inhibit amyloid formation, and translates the results to clinically relevant models.