stREAM OverVIEW
BAM RESEARCH STRATEGY
DEVELOP a research question related to drug discovery.
DESIGN small molecules with related bioactivity.
SYNTHESIZE, purify, & characterize compounds.
OPTIMIZE chemical reactions & rationalize data.
WHAT LAB TECHNIQUES DO WE PERFORM?
REACTION OPTIMIZATION
Reaction Stoichiometry, Schlenk (Airfree) technique, extraction, microscale mult-step synthesis and reactions.
SEPARATION & PURIFICATION
Extraction, Column & Thin Layer Chromatography (TLC), distillation, recrystallization.
STRUCTURAL IDENTIFICATION
Infrared (IR) & Nuclear Magnetic Resonance (NMR) Spectroscopy
COMPUTATIONAL METHODS & COLLABORATION.
PyMOL, ChemDraw, Reaxys, Research Poster-Preparation, Presentations, AI Drug Disocvery
COURSE CREDIT
Spring Semester | NSC 109 & CH204 (3 credits). Students will learn wet-laboratory techniques in organic chemistry for the synthesis, isolation, purification and characterization of small organic molecules and the scientific concepts behind the experiments.
Fall Semester | CH220c (2 credits) or CH369K or BIO377 (both 3 credits). Students will review lab techniques and work on individual synthesis projects related to the field of drug discovery.
Peer Mentors | CH368L (3 credits). Peer Mentors are students who have previously completed the two semester sequence with BAM. By annual application only.
SUMMER RESEARCH
First year students are encouraged to apply for the FRI Summer Research Fellowship or continue to work in the lab over the summer as a volunteer researcher. Advanced students (those who completed the BAM course sequence) can apply for the CNS Advanced Summer Research Fellowship to continue their project related to stream research. Summer research is NOT REQUIRED to continue in the fall.