Objectives of Org(SB-EAI)

1. Theoretical construction of (target and evolver) models of minimal autopoietic systems implementable in wetware models

2. Determining techniques, approaches and materials to proceed to the chemical implementation of the wetware (target and evolver) systems previously defined

3. Definition of a set of criteria to evaluate the relevance of wetware models of biological and cognitive processes for the advancement of the scientific understanding of life and cognition

4. Determination of the applicative potentialities of these models and definition of guidelines for an effective and sustainable experimental follow up of the project

ublic Engagement

1. 2024-mm-gg: Website (prin-2022-org-sb-eai)

2. 2024-09-27: Poster at the European Researchers' Night (ex Monastero degli Olivetani, Lecce)

Workshops

1. 2024-07-25: L. Damiano, P. Stano, Y. Kuruma, Organization of the workshop "SB-AI 9. From imitative to biologically plausible synthetic models of natural cognition" as a satellite event of the ALIFE-2024 hybrid conference, Copenhagen.

2. 2025-09-11: I. Alfieri, A. Fleres,  R. Mannocci, H. Lehmann, L. Damiano, Organization of the Special Session 03 "Social Robotics and Sustainability - Transdisciplinary dialogues on social robots’ philosophical, scientific and technological innovation" at the International Conference on Social Robotics + AI (ICSR+AI 2025) , Naples 10-12 September 2025.

3. 2025-09-24: P. L. Gentili, D. Magri, J. Gorecki, P. Stano, Organization of the MDPI Topic webinar "Recent Advances in Chemical Artificial Intelligence by Exploring Molecular Systems"

4. 2025-10-09: L. Damiano, A. Fleres, Y. Kuruma, A. Roli, P. Stano, Organization of the workshop "SB-AI 10: Self-organization in (nano and electromechanical) robots. Towards the robosphere" as a satellite event of the ALIFE-2025 hybrid conference, Kyoto, 6-10 October 2025.

Talks and Lectures

1. 2024-07-23: S. Rubin "Models and Simulations of the Living forms", presented at the workshop The Fourth Workshop on Chemistry and Artificial Life Forms (Chemaliforms IV) , a satellite event of The 2024 Conference on Artificial Life (ALIFE2024), Copenhagen, Denmark. (online)

2. 2024-07-25: S. Rubin "Theoretical Cartography of Autopoiesis", presented at the SB-AI 9. From imitative to biologically plausible synthetic models of natural cognition, a satellite event of  The 2024 Conference on Artificial Life (ALIFE2024), Copenhagen, Denmark. (online)

3. 2024-09-03: P. Stano "Systems Chemistry", a lecture for PhD students of the course "Environmental and Biological Sciences and Technologies" DiSTeBA-Unisalento (in presence)

4. 2024-09-11: S. Rubin "Steps to chemically embodied cognition", presented at The WIVACE 2024. XVIII International Workshop on Artificial Life and Evolutionary Computation, Namur, Belgium. (in presence)

5. 2024-09-12: S. Rubin "Sense-making in Embodied AI – Towards Autopoietic Chemical AI", presented at The 28th World Multiconference on Systemics, Cybernetics and Informatics (WMSCI), Special Track on Knowledge and Cognitive Science and Technologies, Florida, US. (online)

6. 2025-09-04: A. Fleres, L. Damiano "Toward a Gaian Synthetic Approach. Techno-Apoptosis as a Catalyst for Sustainable Robotics", presented at The WIVACE 2025. XIX International Workshop on Artificial Life and Evolutionary Computation, Siena, Italy, 3-5 September 2025. (in presence)

7. 2025-09-17: L. Damiano, P. Dumouchel "Beyond Strong Social Robotics. A Relational Perspective", presented at The 4th International Conference on Human and Artificial Rationalities (HAR 2025), Paris, 16-19 September 2025. (online)

Publications

1. Del Moro, L.; Magarini, M.; Stano, P. Semantic Information as a Measure of Synthetic Cells’ Knowledge of the Environment. In: “Artificial Life and Evolutionary Computation. 17th Italian Workshop, WIVACE 2023, Venice, Italy, September 6–8, 2023, Revised Selected Papers”, M. Villani, S. Cagnoni, R. Serra (Eds.). Springer, Cham (CH). Communications in Computer and Information Science 2024, 1977, 98-110. (link)

2. Damiano, L.; Stano, P. General Lines, Routes and Perspectives of Wetware Embodied AI. From its Organizational Bases to a Glimpse on Social Chemical Robotics. In: “Artificial Life and Evolutionary Computation. 17th Italian Workshop, WIVACE 2023, Venice, Italy, September 6–8, 2023, Revised Selected Papers”. M. Villani, S. Cagnoni, R. Serra (Eds.). Springer, Cham (CH). Communications in Computer and Information Science 2024, 1977, 111-122. (link)

3. Gentili, P. L.; Stano, P. Living Cells and Biological Mechanisms as Prototypes for Developing Chemical Artificial Intelligence. Biochemical and Biophysical Research Communications 2024, 720, 150060. (link)

4. Roli, A.; Braccini, M.; Stano, P. On the positive role of noise and error in complex systems. MDPI Systems 2024, 12, 338. (link)

5. Gentili, P. L.; Zurlo, M. P.; Stano, P. Neuromorphic Engineering in Wetware: The State of the Art and Its Perspectives. Frontiers in Neuroscience 2024, 18, 1443121. (link)

6. Rubin, S.; Stano, P.; Roli, A.; Damiano, L. Sense-making in Embodied AI. Towards Autopoietic Chemical AI. In: Proceedings of The 28th World Multi-Conference on Systemics, Cybernetics and Informatics (WMSCI 2024); 10-13 September 2024, Virtual Conference. N. Callaos, E. Gaile-Sarkane, N. Lace, B. Sánchez, M. Savoie (Eds.). The International Institute of Informatics and Cybernetics; Winter Garden (FL), USA. 2024, pp. 85-91. (link)

7. Gentili, P. L.; Stano, P. Empowering Chemical AI through Systems Chemistry. ChemSystemsChem 2024, 6, e202400054. (link)

8. Rubin, S.; Stano, P.; Roli, A.; Damiano, L. Steps to Chemically Embodied Cognition. In: Artificial Life and Evolutionary Computation, 18th Italian Workshop, WIVACE 2024, Namur, Belgium, September 11–13, 2024, Revised Selected Papers; T. Carletti; T. S. Njougouo; E. Tuci (Eds.); Springer, Cham (CH). Communications in Computer and Information Science 2025, 2532, 84-97. (link)

Special Issues

1. Gentili, P. L.; Jerzy Górecki, J.; Magri, D. C.; Stano, P. Recent Advances in Chemical Artificial Intelligence. MDPI Special Topic hosted by the following journals: Molecules, Biomimetics, Chemsensors, Life, AI, Sci. (link)

2. Gentili, P. L.; Adamatzsky, A.; Stano, P. Neuromorphic Engineering in wetware: achievements and perspectives. Frontiers Research Topic hosted by the following journals: Frontiers in Bioengineering and Biotechnology, Frontiers in Chemistry, Frontiers in Neurorobotics, Frontiers in Physics, Frontiers in Robotics and AI. (link)

3. Braccini, M.; Roli, A.; Stano, P. Hypothesis-Driven Artificial Intelligence Approaches for Complex Systems Biology. MDPI Special Issue hosted by the journal: Systems. (link)

Scientific Exchanges

Academic Orientation for High-School Students

1. 2023-10-24: P. Stano, "Cellule Sintetiche: dall'Origine della Vita alla Biologia Sintetica", talk at the Open Day 2023 Unisalento (CdL in Scienze Biologiche)

2. 2024-02-19: P. Stano, "Synthetic Cells and Chemical AI", talk at PCTO-DiSTeBA Unisalento (CdL in Scienze Biologiche)

3. 2024-02-21: P. Stano, "Synthetic Cells and Chemical AI", talk at PCTO-DiSTeBA Unisalento (CdL in Biotecnologie Mediche e Nanobiotecnologie)

4. 2024-02-22: P. Stano, "Sistemi chimici per la nanomedicina e cenni alla Chemical AI", talk for Orientamento Attivo Unisalento (Liceo Scientifico Statale Giulietta Banzi Bazoli, Lecce)

5. 2024-02-28: P. Stano, "Sistemi chimici per la nanomedicina e cenni alla Chemical AI", talk for Orientamento Attivo Unisalento (Istituto Tecnico Grazia Deledda, Lecce)

6. 2024-10-29: P. Stano, "Dall'Origine della Vita alla Biologia Sintetica", talk at the Open Day 2024 Unisalento, (CdL in Scienze Biologiche)

7. 2025-02-13: P. Stano, "Cellule sintetiche: dall'origine della vita alla biologia sintetica", talk at PCTO-DiSTeBA Unisalento (CdL in Biotecnologie)

Meetings

1. 2025-10-25: Project meeting

2. 2023-12-13: Kick-off meeting (Cesena)

3. 2024-01-31: Project meeting

4. 2024-03-07: Project meeting

5. 2024-04-08: Project meeting

6. 2024-05-23: Project meeting

7. 2024-05-28: Project meeting

8. 2024-07-02: Project meeting

9. 2024-08-02: Project meeting

10. 2024-09-25: Project meeting

11. 2024-10-07: Project meeting

12. 2024-10-28: Project meeting

13. 2024-11-29: Project meeting

14. 2024-12-07: Project meeting

15. 2024-12-16/17: Mid-term meeting (Milano)

16. 2025-02-17: Project meeting

17. 2025-03-14: Project meeting

18. 2025-04-08: Project meeting

19. 2025-04-14: Project meeting

20. 2025-05-09: Project meeting

21. 2025-06-06: Project meeting

22. 2025-07-11: Project meeting