PROGRAM

July 4th

14.30 Opening and registration

First session - Chair: Luciana Mosca and Andrea Fuso (Sapienza University of Roma, Italy)

15.30- Introduction 

15.30 - 16.15   PLENARY LECTURE   Annalisa Pastore (King’s college, London, UK) The biophysics of the interaction between TDP-43 and phospholipids: a dangerous liaison?

16.15 - 17.00   Fabrizio Chiti  (University of Florence, Italy) Studies of protein misfolding and aggregation. A biophysical approach

17.00 - 17.30   Giovanni Longo (National Research Council, Institute of Material Structure, Italy) Probing amyloid multispecies cooperative effect on neurons at the single cell level

17.30 - 18.00 - Coffee break & poster session

18.00 - 18.30  Andrea Ilari (National Research Council, IBPM, Italy) Investigation of the binding mechanism and molecular nature of σ1 receptor Ligands

18.30 - 19.30  Selected talks from the abstracts:

Giorgio  Buttitta (Sapienza University of Roma, Italy) Sphingosomal and liposomal encapsulation of a synthetic MAO-B inhibitor: a novel approach to neurotherapeutics

Greta Massa (Sapienza University of Roma, Italy) From neurodevelopmental vulnerability to neurodegeneration: synaptic and behavioral signatures in a lysosomal lipid disorder mouse model

Michele Coluccia (Sapienza University of Roma, Italy) Investigating the 2-aroylbenzofuran scaffold: novel human monoamine oxidase B inhibitors against neurodegenerative diseases

Francesca Arrighi (Sapienza University of Roma, Italy) Novel insights on benzo[b]thiophen analogues for Parkinson’s disease: design, synthesis, molecular modelling studies and biological activity

19.30 - Social dinner, poster session & networking

July 5th

Second session - Chair: Adriana Erica Miele (Université Claude Bernard Lyon 1, France), Andrea Ilari (National Research Council, Italy)

9.00 - 9.30   David Vauzour (University of East Anglia, Norwich, UK) Impact of dietary polyphenols on brain functions through the gut-brain axis modulation

9.30 - 10.00  Andrea Fuso (Sapienza University of Roma, Italy) DNA methylation and microRNAs cross-talk in Alzheimer’s Disease

10.00 - 11.00  Selected talks from the abstracts:

Paola Coccetti (University of Milano-Bicocca, Italy) Protective role of verbascoside against misfolding and aggregation of α-synuclein associated with Parkinson’s disease

Erica Costantini (University G. d’Annunzio of Chieti-Pescara, Italy) TNF-α in MS disease: evaluation of miRNA–mRNA and Protein levels

Marianna Nicoletta Rossi (University of Roma Tre, Italy) Transcriptomic analysis reveals the beneficial effects of spermidine in an ALS mouse model

Noemi Colozza (Istituto di Struttura della Materia, CNR, Italy) 3D-Printed innovative tools for in-situ cell sensing in neurodegenerative diseases 

11.00-11.30 - Coffee break

11.30 - 12.00  Cristina Angeloni (University of Bologna Alma Mater, Bologna, Italy) New molecular targets in neuroinflammation

12.00 - 12.30  Sophie Ayciriex Daniel Di Risola (Sapienza University of Roma, Italy) Lipidomics in Alzheimer’s disease

12.30 - 13.00  Laura Di Renzo (Tor Vergata University, Roma, Italy) Exposome and Alzheimer’s disease

13.00 - 13.15 - Award ceremony (best abstract, best poster)

13.15 - 13.30 - Concluding remarks and future perspectives   

13.30 - Light lunch