Papers

Heck, TG. What artificial intelligence knows about 70 kDa heat shock proteins, and how we will face this ChatGPT era. Cell Stress and Chaperones, 2023

Costa-Beber et al. Air pollution combined with high-fat feeding aggravates metabolic and cardiovascular diseases: A dangerous, oxidative, and immune-inflammatory association. Life Sciences, 2023.

De Batista et al. Disturbance of cellular calcium homeostasis plays a pivotal role in glyphosate-based herbicide-induced oxidative stress. Environmental Science and Pollution Research, 2023.

Dos Santos et al. Moderate aerobic training is safe and improves glucose intolerance induced by the association of high fat diet and air pollution. Environmental Science and Pollution Research, 2023.

Sulzbacher et al. Adapted Murine Sepsis Score: Improving the Research in Experimental Sepsis Mouse Model. Biomed Research International, 2022.

Hirsch, G. E.; Heck, T.G. Inflammation, oxidative stress and altered heat shock response in type 2 diabetes: the basis for new pharmacological and non-pharmacological interventions. Archives of Physiology and Biochemistry, 2022.

Santos, J. M.; Heck, T.G. Oxidative stress in type 2 diabetes and the impact of exercise: from mitochondria to glucose management in skeletal muscle. Revista Contexto & Saúde, 2022.

Seibert et al. Increased eHSP70-to-iHSP70 ratio in prediabetic and diabetic postmenopausal women: a biomarker of cardiometabolic risk. Cell Stress & Chaperones, 2022. 

Dos Santos et al. Moderate aerobic training is safe and improves glucose intolerance induced by the association of high fat diet and air pollution. Environmental Science and Pollution Research, 2022.

Heck et al. Insufficient social distancing may contribute to COVID-19 outbreak: The case of Ijuí city in Brazil. PLoS One, 2021.

Costa-Beber et al. Ovariectomy reduces the cardiac cytoprotection in rats exposed to particulate air pollutant. Environmental Science and Pollution Research, 2021.

Costa-Beber et al. Ovariectomy enhances female rats' susceptibility to metabolic, oxidative, and heat shock response effects induced by a high-fat diet and fine particulate matter. Experimental Gerontology, 2021.

Kostrycki, et al. Effects of Water Temperature on Blood Lactate Concentration in Swimming Exercise Rat Model. Journal of Exercise Physiology Online, 2021. 

Stefani et al.  Effects of aerobic and resistance exercise training associated with carnosine precursor supplementation on maximal strength and O2max in rats with heart failure. Life Sciences, 2021.

Anklam et al.  Oxidative and Cellular Stress Markers in Postmenopause Women with Diabetes: The Impact of Years of Menopause. Journal of Diabetes Research, 2021.

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Costa-Beber et al. HSP70 as a biomarker of the thin threshold between benefit and injury due to physical exercise when exposed to air pollution. Cell Stress & Chaperones, 2021.

Mesenburg et al. Prevalence of symptoms of COVID-19 in the state of Rio Grande do Sul: results of a population-based study with 18,000 participants. Revista de Saúde Publica (online), 2021.

Heck, T.G.  Cardioprotection during Chemotherapy: Prospects of Antioxidant Strategies. Arquivos Brasileiros de Cardiologia, 2021.

Costa-Beber et al. The association of subchronic exposure to low concentration of PM2.5 and high-fat diet potentiates glucose intolerance development, by impairing adipose tissue antioxidant defense and eHSP72 levels. Environmental Science and Pollution Research, 2020.

Heck et al. Suppressed anti-inflammatory heat shock response in high-risk COVID-19 patients: lessons from basic research (inclusive bats), light on conceivable therapies. Clinical Science, 2020.

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Sulzbacher et al. A single dose of eHSP72 attenuates sepsis severity in mice. Scientific Reports, 2020.

Costa-Beber et al. Chaperone duality: the role of extracellular and intracellular HSP70 as a biomarker of endothelial dysfunction in the development of atherosclerosis. Archives of Physiology and Biochemistry, 2020.

Lissarassa et al.  Chronic heat treatment positively impacts metabolic profile of ovariectomized rats: association with heat shock response pathways. Cell Stress and Chaperones, 2020.

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Hirsch and Heck. Inflammation, oxidative stress and altered heat shock response in type 2 diabetes: the basis for new pharmacological and non-pharmacological interventions. Arch Physiol Biochem, 2019 .

Goettems-Fiorin et al. Ovariectomy predisposes female rats to fine particulate matter exposure’s effects by altering metabolic, oxidative, pro-inflammatory, and heat-shock protein levels. Environmental Science and Pollution Research, 2019.

Kostrycki et al. Effects of High-Fat Diet on eHSP72 and Extra-to-Intracellular HSP70 Levels in Mice Submitted to Exercise under Exposure to Fine Particulate Matter. Journal of Diabetes Research, 2019. 

Corrêa et al. Characterization of Schinus lentiscifolius Marchand (Anacardiaceae) Bark Extract and Its Effects on Lymphocyte Oxidative Stress and Heat Shock Response.  Chemistry & Biodiversity, 2019.

Bender dos Santos, et al. Incremental Swimming Exercise Test: A Protocol to Evaluate Physical Performance in Rats. Journal of Exercise Physiology. August 2018.  Volume 21, Number 4.

Stefani et al.  Resistance training and L-arginine supplementation are determinant in genomic stability, cardiac contractility and muscle mass development in rats. PLoS One, v. 13, p. e0204858, 2018.

Ten Caten Martins et al. Detectable levels of eHSP72 in plasma are associated with physical activity and antioxidant enzyme activity levels in hypertensive subjects. CELL STRESS & CHAPERONES, v. 23, p. 1319-1327, 2018.

Baldissera et al. Subacute exposure to residual oil fly ash (ROFA) increases eHSP70 content and extracellular-to-intracellular HSP70 ratio: a relation with oxidative stress markers. Cell Stress Chaperones. 2018.

Sulzbacher et al. Efeitos do tratamento com glutamina via enteral em modelo animal de sepse. SAÚDE (SANTA MARIA), v. 44, p. 1-10, 2018.

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Mai et al. Exercise training under exposure to low levels of fine particulate matter: effects on heart oxidative stress and extra-to-intracellular HSP70 ratio. Oxidative Medicine and Cellular Longevity, 2018.

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Heck et al. Acute exercise boosts cell proliferation and the heat shock response in lymphocytes: correlation with cytokine production and extracellular-to-intracellular HSP70 ratio.  Cell Stress Chaperones. 2017; ​Mar;22(2):271-291.

Kostrycki et al. Hematological Response of Acute Exercise in Obese Mice: The Obesity Attenuation Effect on Leukocytes Response. J. of Exer. Physiol. Online. 2016;  72:643–656.

Schöler et al. Modulation of rat monocyte/macrophage innate functions by increasing intensities of swimming exercise is associated with heat shock protein status. Mol Cell Biochem. 2016 Oct;421(1-2):111-25

Goettems-Fiorin et al, Fine particulate matter potentiates type 2 diabetes development in high-fat diet-treated mice: stress response and extracellular to intracellular HSP70 ratio analysis. J Physiol Biochem. 2016 Dec;72(4):643-656

Grochanke et al. Compostos fenólicos da casca de Handroanthus heptaphyllus (Mart.) Mattos e efeitos do extrato aquoso no perfil lipídico, glicêmico e na lipoperoxidação em ratos diabéticos. Revista Brasileira de Plantas Medicinais, v. 18, p. 264-272, 2016.

Heck et al. Subclinical Processes in the Development of Type Two Diabetes. Journal of Novel Physiotherapies, v. 5, p. 246, 2015.

Krause et al. The Chaperone Balance Hypothesis: The Importance of the Extracellular to Intracellular HSP70 Ratio to Inflammation-Driven Type 2 Diabetes, the Effect of Exercise, and the Implications for Clinical Management. Mediators of Inflammation (Print), v. 2015, p. 1-12, 2015.

Abreu-Silva et al. Effects of Physical Activity on The Inflammatory Process Related to Insulin Resistance and Obesity. International Journal of Cardiology and Lipidology Research, v. 2, p. 20-26, 2015.

Abreu-Silva et al. Diet and Inflammation: Effects of Macronutrients and Dietary Patterns. International Journal of Cardiology and Lipidology Research, v. 2, p. 7-13, 2015.

Petry et al. L-glutamine Supplementations Enhance Liver Glutamine-Glutathione Axis and Heat Shock Factor-1 Expression in Endurance-Exercise Trained Rats. International Journal of Sport Nutrition and Exercise Metabolism (Print), v. 25, p. 188-197, 2015.

Nunes et al. Hemodynamic Responses during an Incremental Swimming Exercise Test in Rats. Journal of Exercise Physiology Online, v. 18, p. 55-62, 2015.

Krause et al. Heat shock proteins and heat therapy for type 2 diabetes. Current Opinion in Clinical Nutrition and Metabolic Care, v. 18, p. 374-380, 2015.

Stefani et al. Metabolic Syndrome and DNA Damage: The Interplay of Environmental and Lifestyle Factors in the Development of Metabolic Dysfunction. Open Journal of Endocrine and Metabolic Diseases, v. 05, p. 65-76, 2015.

Miragem et al. Estrogen deprivation does not affect vascular heat shock response in female rats: a comparison with oxidative stress markers. Molecular and Cellular Biochemistry, v. 407, p. 239-249, 2015.

Goettems-Fiorin et al. Exposure to particulate matter modifies the pancreas extracellular/intracellular HSP70 ratio in high-fat diet treated mice: a marker of the diabetes development risk. Diabetology & Metabolic Syndrome, v. 7, p. A147, 2015.

Horn et al. Avaliação dos Níveis de Estresse Oxidativo em Pacientes Fumantes Crônicos. Revista On line Contexto e Saúde da UNIJUI, v. 15, p. 97-103, 2015.

Heck et al. Residual Oil Fly Ash (ROFA) Inhalation Promotes Lung and Heart Oxidative Stress without Hemodynamic Effects in Exercising Rats. Journal of Exercise Physiology Online, v. 17, p. 78-89, 2014.

Petry et al. Alanyl-glutamine and glutamine plus alanine supplements improve skeletal redox status in trained rats: Involvement of heat shock protein pathways. Life Sciences (1973), v. 94, p. 130-136, 2014.

Heck et al. Effects of Ambient Particles Inhalation on Lung Oxidative Stress Parameters in Exercising Rats. Journal of Exercise Physiology Online, v. 17, p. 58-69, 2014.

Goettems-Fiorin et al. O Ensino Interdisciplinar na Área da Saúde: Perspectivas para a formação e a atuação multiprofissional. Revista Didática Sistêmica, v. 16, p. 30-43, 2014.

Ulbrich et al. Concordância entre impedância bioelétrica e dobra cutânea para determinação da composição corporal de adolescentes. Revista Brasileira Ciências da Saúde, v. 18, p. 19-24, 2014.

Ludwig et al. Short-term but not long-term hypoglycaemia enhances plasma levels and hepatic expression of HSP72 in insulin-treated rats: an effect associated with increased IL-6 levels but not with IL-10 or TNF-α. Molecular and Cellular Biochemistry, v. 397, p. 97-107, 2014.

Knabben et al. Valor de referência da circunferência da cintura a partir do percentil 85 do imc de adolescentes. Biomotriz (UNICRUZ), v. 8, p. 77-93, 2014.

Heck, T.G. Pharmacology and Exercise: An Essential Discipline and Research Area in Health Courses. Journal of Novel Physiotherapies, v. 03, p. e128, 2013.

Souza et al. Effects of creatine supplementation on biomarkers of hepatic and renal function in young trained rats. Toxicology Mechanisms and Methods, v. 23, p. 1-20, 2013.

Ulbrich et al. Influence of intensity of dynamic training on HSP70 expression by peripheral blood mononuclear cells from patients with chronic heart failure: a randomized controlled trial. European Heart Journal, v. 34, p. p5782-p5783, 2013.

Heck et al. Iniciação Científica no Ensino Médio: um Modelo de Aproximação da Escola com a Universidade por Meio do Método Científico. RBPG. Revista Brasileira de Pós-Graduação, v. 8, p. 447-465, 2012.

Heck, T.G. The Translational Science as Novel Physiotherapy. Journal of Novel Physiotherapies, v. 02, p. 1000e122, 2012.

Sulzbacher et al.Desenvolvimento de modelo experimental de sepse para avaliação dos efeitos com glutamina sobre a HSP70 e Estresse Oxidativo. Revista Contexto & Saúde, v. 22, p. 85-87, 2012.

Heck et al. HSP70 expression: does it a novel fatigue signalling factor from immune system to the brain?. Cell Biochemistry and Function, v. 29, p. 215-226, 2011.

Nunes et al. Physical exercise improves plasmatic levels of IL-10, left ventricular end-diastolic pressure, and muscle lipid peroxidation in chronic heart failure rats. Journal of Applied Physiology, v. 104, p. 1641-1647, 2008.

Pereira et al. Ambient particulate air pollution from vehicles promotes lipid peroxidation and inflammatory responses in rat lung. Brazilian Journal of Medical and Biological Research, v. 40, p. 1353-1359, 2007.

Homem de Bittencourt Jr et al. LipoCardium: Endothelium-directed cyclopentenone prostaglandin-based liposome formulation that completely reverses atherosclerotic lesions. Atherosclerosis (Amsterdam), v. 193, p. 245-258, 2007.

Kolberg et al. Low expression ofMRP1/GS-X pump ATPase in lymphocytes of Walker 256 tumour-bearing rats is associated with cyclopentenone prostaglandin accumulation and cancer immunodeficiency. Cell Biochemistry and Function, v. 24, p. 23-39, 2006.Kostrycki, I.M.