Selected Publications

1. Prisco SZ, Hartweck LM, Kazmirczak F, Mendelson JB, Deng SL, Blake M, Lahiri SK, Wehrens XHT, Prins KW. Junctophilin-2 Regulates Mitochondrial Metabolism. Circulation. 2024 Aug 20;150(8):657-660. doi: 10.1161/CIRCULATIONAHA.123.064343. Epub 2024 Aug 19. 

2. Mendelson JB, Sternbach JD, Doyle MJ, Mills L, Hartweck LM, Tollison W, Carney JP, Lahti MT, Bianco RW, Kalra R, et al. Multi-omic and multispecies analysis of right ventricular dysfunction. J Heart Lung Transplant. 2024;43:303-313. doi: 10.1016/j.healun.2023.09.020

3. Blake M, Puchalska P, Kazmirczak F, Blake J, Moon R, Thenappan T, Crawford PA, Prins KW. Ketone bodies in right ventricular failure: A unique therapeutic opportunity. Heliyon. 2023;9:e22227. doi: 10.1016/j.heliyon.2023.e22227

4. Kazmirczak F, Thenappan T, Prins KW, Prisco SZ. Sex differences in right ventricular function between Groups 1 and 3 pulmonary hypertension. Pulm Circ. 2023;13:e12288. doi: 10.1002/pul2.12288

5. Moutsoglou DM, Tatah J, Prisco SZ, Prins KW, Staley C, Lopez S, Blake M, Teigen L, Kazmirczak F, Weir EK, et al. Pulmonary Arterial Hypertension Patients Have a Proinflammatory Gut Microbiome and Altered Circulating Microbial Metabolites. Am J Respir Crit Care Med. 2023;207:740-756. doi: 10.1164/rccm.202203-0490OC

6. Kazmirczak F, Hartweck LM, Vogel NT, Mendelson JB, Park AK, Raveendran RM, O-Uchi J, Jhun BS, Prisco SZ, Prins KW. Intermittent Fasting Activates AMP-Kinase to Restructure Right Ventricular Lipid Metabolism and Microtubules. JACC Basic Transl Sci. 2023;8:239-254. doi: 10.1016/j.jacbts.2022.12.001

7. Kazmirczak F, Prisco SZ, Knoper R, Huddleston S, Raveendran G, Pritzker M, Thenappan T, Prins KW, Gurevich S. Effect of Combination of Balloon Pulmonary Angioplasty and Medical Therapy on Reverse Right Ventricular Remodeling and Hemodynamics in Chronic Thromboembolic Pulmonary Hypertension. J Invasive Cardiol. 2023;35:E312-E320. doi: 10.25270/jic/23.00060

8. Chang KY, Giorgio K, Schmitz K, Walker RF, Prins KW, Pritzker MR, Archer SL, Lutsey PL, Thenappan T. Effect of Chronic Digoxin Use on Mortality and Heart Failure Hospitalization in Pulmonary Arterial Hypertension. J Am Heart Assoc. 2023;12:e027559. doi: 10.1161/JAHA.122.027559

9. Prisco SZ, Hartweck L, Keen JL, Vogel N, Kazmirczak F, Eklund M, Hemnes AR, Brittain EL, Prins KW. Glyoxylase-1 combats dicarbonyl stress and right ventricular dysfunction in rodent pulmonary arterial hypertension. Front Cardiovasc Med. 2022;9:940932. doi: 10.3389/fcvm.2022.940932

10. Prisco SZ, Hartweck LM, Rose L, Lima PDA, Thenappan T, Archer SL, Prins KW. Inflammatory Glycoprotein 130 Signaling Links Changes in Microtubules and Junctophilin-2 to Altered Mitochondrial Metabolism and Right Ventricular Contractility. Circ Heart Fail. 2022;15:e008574. doi: 10.1161/CIRCHEARTFAILURE.121.008574

11. Tatah J, Keen JL, Prisco SZ, Pritzker M, Thenappan T, Prins KW. Iron Deficiency is Associated with More Severe Pulmonary Vascular Disease in Pulmonary Hypertension due to Chronic Lung Disease. Chest. 2021. doi: 10.1016/j.chest.2021.07.2159

12. Prisco SZ, Eklund M, Raveendran R, Thenappan T, Prins KW. With No Lysine Kinase 1 Promotes Metabolic Derangements and RV Dysfunction in Pulmonary Arterial Hypertension. JACC Basic Transl Sci. 2021;6:834-850. doi: 10.1016/j.jacbts.2021.09.004

13. Prisco SZ, Eklund M, Moutsoglou DM, Prisco AR, Khoruts A, Weir EK, Thenappan T, Prins KW. Intermittent Fasting Enhances Right Ventricular Function in Preclinical Pulmonary Arterial Hypertension. J Am Heart Assoc. 2021;10:e022722. doi: 10.1161/JAHA.121.022722

14. Thenappan T, Weir EK, Prins KW, Pritzker MR, Archer SL. Carvedilol for Treatment of Right Ventricular Dysfunction in Pulmonary Arterial Hypertension. J Am Heart Assoc. 2021;10:e021518. doi: 10.1161/JAHA.121.021518

15. Kalra R, Duval S, Thenappan T, Raveendran G, Pritzker M, Prisco SZ, Prins KW. Comparison of Balloon Pulmonary Angioplasty and Pulmonary Vasodilators for Inoperable Chronic Thromboembolic Pulmonary Hypertension: A Systematic Review and Meta-Analysis. Sci Rep. 2020;10:8870. doi: 10.1038/s41598-020-65697-4

16. Prins KW, Kalra R, Rose L, Assad TR, Archer SL, Bajaj NS, Weir EK, Prisco SZ, Pritzker M, Lutsey PL, et al. Hypochloremia Is a Noninvasive Predictor of Mortality in Pulmonary Arterial Hypertension. J Am Heart Assoc. 2020;9:e015221. doi: 10.1161/JAHA.119.015221