Awards/Featured JournalArticles
Alternaria allergen exposure stimulates the regulated release of genomic and mitochondrial DNA.
Editor's Choice: February 2023
Journal of Allergy and Clinical Immunology (IF 14.29)
Srisomboon, Y. et al., Allergen-induced DNA release by the airway epithelium amplifies type 2 immunity, J Allergy Clin Immunol., 151(2):494-508, 2023.
Highlighted as a featured article in the February 2023 issue of the journal: https://doi.org/10.1016/j.jaci.2022.09.034
Mechanism of conductive ATP release mediated by apical VDAC-1 channels following Alternaria exposure.
Editor's Choice: May, 2020
Journal of Physiology (IF: 6.23)
Srisomboon, Y. et al., Fungal allergen-induced IL-33 secretion involves cholesterol-dependent, VDAC-1-mediated ATP release from the airway epithelium, J. Physiol. 598(10):1829-1845, 2020.
Highlighted as a featured article in the May 2020 issue of the journal: https://doi.org/10.1113/JP279379, this paper was the subject of a Perspectives article entitled “Treating fungus-induced allergic asthma: Do VDACs have the answer!” at doi.org/10.1113/JP279703
Srisomboon, Y. et al., 2020, Journal of Physiology, doi.org/10.1113/JP279379
Cover: Journal of Physiology
Apical colocalization of VDAC-1 with Caveolin-1 in hBE cells.
Confocal image (600x) of human bronchial epithelial (hBE) cells labeled with anti-VDAC-1 and anti-Caveolin-1 antibodies. Colocalization of VDAC-1 and Caveolin-1 indicated in yellow. Srisomboon Y, Squillace DL, Maniak PJ, Kita H, O'Grady SM. Fungal allergen-induced IL-33 secretion involves cholesterol-dependent, VDAC-1-mediated ATP release from the airway epithelium. J Physiol., 598 (10):1829-1845. 2020.
P2Y2 receptor regulation of apical BK channels (KCNMA1) in human bronchial epithelial cells. Hydrocortisone suppresses the expression of STREX-containing KCNMA1 subunits, allowing for activation of the channel by P2Y2R mediated increases in the intracellular calcium concentration.
Editor's Choice: July 2017
Journal of Physiology (IF: 6.23)
Zaidman, N.A. et al., Large-conductance Ca2+ -activated K+ channel activation by apical P2Y receptor agonists requires hydrocortisone in differentiated airway epithelium, 595(14):4631-4645, 2017.
Highlighted as a featured article in the July 2017 issue of the journal: https://doi.org/10.1113/JP274200, this paper was the subject of a Perspectives article entitled “Exocrine secretion spelled with a capital K (BK)” at https://doi.org/10.1113/JP274588.
APSselect Award: June 2017
For distinguished scholarship in the American Journal of Physiology [Cell Physiology] for the article "Airway epithelial anion secretion and barrier function following exposure to fungal aeroallergens: Role of oxidative stress" Vol 313: C68-C79, 2017. doi.org/10.1152/ajpcell.00043.2017
Presentation of the award to Dr. Nathan Zaidman by Professor Josephine Adams, Editor-in-Chief, at the 2017 Experimental Biology Meetings, Chicago IL
American Journal of Physiology [Cell Physiology]
2016 Paper of the Year Award
Dr. Nathan Zaidman
In a special podcast the Editor-in-Chief of AJP-Cell, Prof. Josephine C. Adams (University of Bristol, UK), has a discussion with the AJP-Cell Paper of the Year 2016 Award winner, Dr. Nathan Zaidman and his mentor, Prof. Scott O'Grady (University of Minnesota, USA). The research underlying the winning paper was carried out as part of Nathan's Ph.D. research in Prof. O'Grady's laboratory. This podcast explores the major findings of the paper entitled, “Differentiation of human bronchial epithelial cells: Role of hydrocortisone in development of ion transport pathways involved in mucociliary clearance”.
APSselect Award: August 2016
For distinguished scholarship in the American Journal of Physiology [Cell Physiology] for the article "Differentiation of human bronchial epithelial cells: role of hydrocortisone in development of ion transport pathways involved in mucociliary clearance" Vol. 311: C225-C236, 2016. doi.org/10.1152/ajpcell.00073.2016
Transfection of GFP-CFTR into CFTR-deficient human airway epithelial cells restores GM-1 expression in the apical membrane.
Featured Article: May, 2014
American Journal of Physiology [Cell Physiology] (IF: 5.28)
Itokazu, Y., et al., Reduced GM1 ganglioside in CFTR-deficient human airway cells results in decreased β1-integrin signaling and delayed wound repair, Am. J. Physiol. [Cell Physiol], 306(9):C819-30, 2014.
Highlighted as a featured article in the May 2014 issue of the journal: 10.1152/ajpcell.00168.2013, this paper was the subject of an Editorial Focus essay entitled “CFTR and GM1 “gangl-ing” up to heal thy wound. Focus on “Reduced GM1 ganglioside in CFTR-deficient human airway cells results in decreased β1-integrin signaling and delayed wound repair” at https://doi.org/10.1152/ajpcell.00075.2014.
Purinergic receptor subtypes expressed in human mammary epithelial cells.
Editor's Choice: July 2011
Journal of Physiology (IF: 6.23)
Palmer M.L. et al., K(Ca)3.1 channels facilitate K+ secretion or Na+ absorption depending on apical or basolateral P2Y receptor stimulation, J. Physiol., 589(Pt 14):3483-94, 2011.
Highlighted as a featured article in the July 2011 issue of the journal: 10.1113/jphysiol.2011.207548. This paper was the subject of a Perspectives article entitled “Clarifying the role of apical K+ channels in Na+ and Cl- transport” at doi.org/10.1113/jphysiol.2011.213116
Impedance sensing arrays were used to measure airway epithelial cell migration during wound closure.
Featured Article: November, 2010
American Journal of Physiology [Cell Physiology] (IF: 5.28)
Schiller, K.R. et al., Cystic fibrosis transmembrane conductance regulator is involved in airway epithelial wound repair, 299(5):C912-21, 2010.
Highlighted as a featured article in the November 2010 issue of the journal: 10.1152/ajpcell.00215.2010, this paper was the subject of an Editorial Focus essay entitled “CFTR channels and wound healing. Focus on “Cystic fibrosis transmembrane conductance regulator is involved in airway epithelial wound repair” at https://doi.org/10.1152/ajpcell.00313.2010.