Aaron Sarver, PhD | sarver@umn.edu
Poster Location: Zone A, Number 13
Mentor: David Largaespada PhD
CSF1R overexpression accelerates osteosarcoma tumors with decreased immune cell infiltration
Authors: Aaron L. Sarver, Justin F. Tibbtts, Nuri A. Temiz, Wendy A. Hudson, David A. Largaespada
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Ashley Schulte, BA | ajgraef@umn.edu
Poster Location: Zone A, Number 14
Mentor: Jaime Modiano, VMD, PhD
Optimization and translation of a flow cytometry protocol for cancer risk prediction in dogs
Authors: Schulte AJ, DePauw TA, Khammanivong A, Winter AL, Stuebner K, Kappenman I, Spielman R, Burt LE, Lewellen M, Borgatti A, Feiock C, Dicovitsky R, Henson MS, Dickerson EB, Chehadeh A, Pracht S, Bergsrud K, Reid K, Espejo-Freire A, Murugan P, Linden MA, Cutter GR, Weigel BJ, Sarver AL, Vallera DA, Modiano JF
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Benjamin Hanson, BS | Hans4984@umn.edu
Poster Location: Zone A, Number 15
Mentor: Hai Dang Nguyen, PhD
Exploring mechanisms of genetic vulnerability to PARP inhibition in splicing factor SF3B1 mutations.
Authors: Hanson BK & Nguyen HD
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Christopher Stehn, BS | stehn007@umn.edu
Poster Location: Zone A, Number 16
Mentor: David Largaespada, PhD
Bio: I am currently a 3rd year PhD student in David Largaespada's lab, studying how epigenetic changes following loss of PRC2 signaling can lead to MPNST tumorigenesis. Originally, I am from Missouri and received my Bachelor's of Science in Biomedical Engineering from the University of Utah, where I worked in the lab of Sheri Holmen.
Characterizing the Super Enhancer Landscape of PRC2 Inactivation in MPNST Development
Authors: Christopher Stehn, BS; Minu Bhunia, BS; Alex Larsson, BS; Kyle Williams, PhD; David Largaespada, PhD
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Daniel Chang, BS | chang682@umn.edu
Poster Location: Zone B, Number 17
Mentor: Zohar Sachs, MD/PhD
Bio: I am a PhD student in the Bioinformatics and Computational Biology program. I am interested in applying machine learning methods to multi-omics datasets to design novel and effective therapeutic strategies.
Sleeping Beauty implicates drivers of leukemic progression in mice with Trp53R270H mutation
Authors: Chang D, Noble-Orcutt K, Iyer A, Hudson W, Pomeroy E, Eckfeldt C, Linden M, Sarver A, Temiz A, Myers CL, Largaespada DA, Sachs Z
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Ester Molina, PhD | molin396@umn.edu
Poster Location: Zone B, Number 18
Mentor: George Aslanidi, PhD
Bio: I am a post-doctoral researcher and I have 8 years of experience in basic cancer research. Recently I have gained expertise in pre-clinical studies and I would like to keep working on this field and hopefully move forward to human clinical trials in the future.
AAV vaccine in a preclinical spontaneous canine model of oral melanoma
Authors: Molina E, Caine C, Krotova K, Kuoch H, Borgatti A and Aslanidi G
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Garrett Draper, BS | drape079@umn.edu
Poster Location: Zone B, Number 19
Mentor: David Largaespada, PhD
Development of a novel syngeneic mouse model that recapitulates NF1-associated tumors
Authors: Draper GM, Panken DJ, Seeman Z, DeTuncq SL, Hudson W, Chen L, Ratner NR, Largaespada DA.
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Jolene Duda, BS | duda0032@umn.edu
Poster Location: Zone B, Number 20
Mentor: Stefani Thomas, PhD
Bio: I am a 4th year graduate student in Stefani Thomas' lab in BMBB. My current research focuses on elucidating drug-induced proteomic changes in ovarian cancer. The overall goal of my research is to establish whether the inhibitors I am studying have functional utility for ovarian cancer treatment.
Establishing the utility of HDAC6 as an ovarian cancer drug target
Authors: Duda JM, Thomas SN
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Lauren Burt, BS | kreag024@umn.edu
Poster Location: Zone B, Number 21
Mentor: Jaime Modiano, VMD, PhD
Defining Chromatin Accessibility in Canine Immune and Osteosarcoma Cells
Authors: Burt LE, Mills LJ, DePauw TA, Modiano JF, Wood CM
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Matthew McMahon, BA
Poster Location: Zone B, Number 22
Mentor: Hai Dang Nguyen, PhD
R-loop accumulation induced by RNA splicing perturbation triggers a discrete PARP2 response
Authors: McMahon MC, Zong D, Liu ZS, Nguyen HD
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Minu Bhunia, BS | bhuni002@umn.edu
Poster Location: Zone B, Number 23
Mentor: David Largaespada, PhD
Bio: Minu graduated from the University of Minnesota in 2018 with a degree in biology and statistics. She is currently a graduate student in MCDBG and BICB in David Largaespada's lab. Her research interests lie in epigenetics and genomics.
Integrative multiomics reveals NOTCH signaling is regulated by PRC2 in human Schwann cells and MPNST
Authors: Bhunia MM, Stehn CM, Madala M, Suppiah S, Novacek E, Jubenville T, Velez-Reyes GL, Larsson AT, Osum SH, Sokolowski M, Zadeh G, Williams KB, Largaesapada DA
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Naohiko Nakamura, PhD, MD | nnakamur@umn.edu
Poster Location: Zone B, Number 24
Mentor: Masato Yamamoto MD, PhD
Antitumor effect of CDX2 promoter-controlled oncolytic adenovirus in esophageal adenocarcinoma
Authors: Nakamura N, Yamamoto M.
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Rahul Bhattacharya, PhD | rbhattac@d.umn.edu
Poster Location: Zone B, Number 25
Mentor: Patricia Scott, PhD and Robert Cormier, PhD
Role of CFTR-deficiency and the gut microbiota in modulating CRC development
Authors: Bhattacharya R , Fletcher J, Blankenheim Z, Cormier RT, Hunter R and Scott PM
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Victor Corral, BS | corra045@umn.edu
Poster Location: Zone B, Number 26
Mentor: Hai Dang Nguyen, PhD
A phosphorylation circuitry of RNase H1 regulates R-loop homeostasis
Authors: Corral VM, Chiraphapphaiboon W, Nguyen HD
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Zhiyan (Silvia) Liu, BA | liu01466@umn.edu
Poster Location: Zone B, Number 27
Mentor: Hai Dang Nguyen, PhD
PARPi selectively kills spliceosome mutant leukemias through R-loop-associated genomic instability
Authors: Liu ZS, Sinha S, Bannister M, Song A, Arriaga-Gomez E, McKeeken AJ, Bonner EA, Hanson BK, Sarchi M, Takashima K, Zong D, Corral VM, Nguyen E, Yoo J, Chiraphapphaiboon W, Leibson C, McMahon MC, Rai S, Swisher EM, Sachs Z, Chatla S, Stirewalt DL, Deeg HJ, Skorski T, Papapetrou EP, Walter MJ, Graubert TA, Doulatov S, Lee SC and Nguyen HD.
Amanda Russel, BA | russe774@umn.edu
Poster Location: Zone B, Number 28
Mentor: Pippa Kennedy, PhD
Bio: Amanda Russell is a researcher investigating NK cell immunotherapies within the Miller consortium (https://sites.google.com/umn.edu/miller). Currently, she is optimizing an in vitro model to investigate tumor cells in a hypoxic environment. She enjoys leading yoga sessions for her colleagues
Hypoxia-acclimated tumor cells are a superior screening tool for novel solid tumor immunotherapies
Authors: Amanda Russell, Rhett Waller, Quinlan M. Kile, Jeffrey S. Miller, Martin Felices, Philippa R. Kennedy
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Gwen Phung, BS | phung036@umn.edu
Poster Location: Zone B, Number 29
Mentor: Jeffrey Miller, MD & Martin Felices, PhD
Bio: My name is Gwen and I am a 5th year PhD student in the Miller/Felices lab. I am developing a new biologic that engages natural killer cells to prostate cancer as a potential new immunotherapy for advance prostate cancer. I am also interested in studying natural killer cell in the tumor microenvironment of solid tumors.
A Tri-specific Killer Engager to enhance specific NK cell targeting of advanced prostate cancer
Authors: Phung SK, Soignier Y, Zorko N, Waller R, Walker J , Nelson T, Selleck C, Bendzick L, Kennedy PR, Miller JS, Felices M
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J.T. Greene, PhD | gree0819@umn.edu
Poster Location: Zone B, Number 30
Mentor: Tanya Freedman, PhD
Bio: I am a cancer researcher working out of the Center for Immunology and studying tumor immunology. I've worked in multiple NCI-designated comprehensive cancer centers during my career, which has spanned translational research in therapeutics, basic cancer biology, and immune cell biology in the tumor microenvironment.
Lyn Kinase Regulates Myeloid-Cell Responses to Mammary Tumors
Authors: J.T. Greene, Ben Brian, Aditi Bapat, Myra Nunez, Tanya Freedman
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Kate Dixon, PhD | dixon097@umn.edu
Poster Location: Zone B, Number 31
Mentor: Bruce Walcheck, PhD
iPSC-derived NK cells expressing high affinity IgG Fc receptor fusion CD64/16A have optimized ADCC
Authors: Kate J. Dixon, Kristin Snyder, Melissa Khaw, Robert Hullsiek, Zachary Davis, Anders Matson, Martin Hosking, Ryan Bjordahl, Bryan Hancock, Soheila Shirinbak, Jeffrey S. Miller, Bahram Valamehr, Jianming Wu, Bruce Walcheck
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Ke Yao, PhD, MD | yaoxx024@umn.edu
Poster Location: Zone B, Number 32
Mentor: Bruce Blazar, MD
Bio: My research focuses on comprehending the underlying mechanisms of induced pluripotent stem cell (iPSC)-derived macrophages with the goal of enhancing phagocytes by equipping them with a chimeric antigen receptor (CAR). The application of CAR-macrophage therapy is directed towards combating tumors that express the targeted antigen.
CAR-expressing Macrophages Derived from Human iPSC Demonstrate Targeted Cancer Killing Activity
Authors: Yao K, Koehn B, Ohtani Y, Allred J, Ma L, Fink J, Dougherty P, Condamine T, Abramson S, Klichinsky M, Blazar BR
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Melissa Khaw, BS | khawx007@umn.edu
Poster Location: Zone C, Number 33
Mentor: Jeffrey Miller, MD and Martin Felices, PhD
Bio: Melissa Khaw is a third-year graduate student in the Comparative Molecular Biosciences PhD program at the University of Minnesota. She is currently working on developing novel NK cell biologics for cancer immunotherapy. She is mentored by both Dr. Martin Felices and Dr. Jeffrey Miller.
Enhancing NK Cell Therapy for Head and Neck Cancer using B7H3-targeting Tri-specific Killer Engager
Authors: Khaw M, Zorko N, Selleck C, Bendzick L, Kennedy P, Shackelford M, Lu A, Fujioka N, Wagner J, MacMillan M, Felices M, Miller JS
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Quinlan Kile, BS | kilex026@umn.edu
Poster Location: Zone C, Number 34
Mentor: Pippa Kennedy, PhD
Bio: Quinlan Kile is a Researcher 2 supervised by Dr. Pippa Kennedy. She graduated with a B.S. in Biology from the University of Minnesota and now investigates the functionality and characteristics of natural killer cells in the context of cancer immunotherapy, with hope of translation to clinical settings.
Differentiation of therapeutic NK cells in 5% oxygen improves control of AML in xenograft models
Authors: Kile QM, Kennedy PR, Waller RL, Bendzick L, Selleck C, Hinderlie P, Kaufman M, Kodal B, Valamehr B, Miller JS, Felices M
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Rhett Waller, BS | walle443@umn.edu
Poster Location: Zone C, Number 35
Mentor: Pippa Kennedy, PhD
Bio: I am a graduate of the Class of '22, having received my BSc in Neuroscience from CBS. I joined the Miller Lab in May of 2022 as a Researcher I and have been investigating the function of iPSC-derived CAR-NK cells in hypoxia under the guidance of Dr. Pippa Kennedy.
A therapeutic CAR-NK cell overcomes hypoxia and suppressive cells to kill colorectal cancer cells
Authors: Waller RL, Phung SK, Kile QM, Valamehr B, Miller JS, Felices M, Kennedy PR
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Robert Hullsiek, BS | hulls015@umn.edu
Poster Location: Zone C, Number 36
Mentor: Bruce Walcheck, PhD
Effects of Blocking ADAM17 on the Generation of Cytokine Induced Memory-Like NK Cells
Authors: Rob H. Hullsiek, Anders W. Matson, Kate J. Dixon, Sam P. Wang, Bruce Walcheck
Alexander Dwyer, PhD, BS | dwyer171@umn.edu
Poster Location: Zone C, Number 37
Mentor: Frank Ondrey, MD PhD
Bio: I completed my undergraduate training in Music Composition and Neurobiology at the University of Wisconsin-Madison. After graduating, I joined the University of Minnesota Medical Scientist Training Program where I completed my PhD in the laboratory of Dr. Brian Fife. I am currently a fourth year medical student applying for residency training positions in otolaryngology.
Otolaryngology Cancer Research Training Program Associated with Academic Success for Trainees
Authors: Dwyer AJ, Elton AC, Wuertz BR, Ondrey FG
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Benu George, PhD | georg949@umn.edu
Poster Location: Zone C, Number 38
Mentor: Beshay Zordoky, PhD
Lingering effects of Doxorubicin on Splenic Immune Cell Subpopulations in C57BL/6 Mice
Authors: George B, Grant MKO, Smith D, Camell CD, Zordoky BN
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Bushra Sadaf, MS | bsadaf@umn.edu
Poster Location: Zone C, Number 39
Mentor: Beshay Zordoky, PhD
Bio: Our lab research focuses on cardio-oncology, with a particular interest in the intersection of cardiovascular disease and cancer.I am strongly dedicated to research and scientific innovation. My goal is to achieve success in this competitive environment by pushing the boundaries of knowledge and creating innovative answers to complex challenges.
Losmapimod modestly reduces DOX-induced cardiotoxicity but compromises its chemotherapeutic efficacy
Authors: Sadaf B, Abdelgawad IY, Daniel MR, Grant MKO, Zordoky BN.
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Julia Kohn, MD | email address
Poster Location: Zone C, Number 40
Mentor: Paolo Goffredo, MD
Bio: Dr. Kohn is a 5th-year resident in the Department of Surgery. Her research and professional interests include colorectal surgery, especially cancer outcomes and LGBT healthcare.
Splenic flexure adenocarcinoma: An analysis of surgical resection and outcomes in the United States
Authors: Kohn JF, Boatman S, Wang Q, Marmor S, Hassan I, Madoff RD, Gaertner WB, Goffredo P
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Lauren Weaver, MD | weave500@umn.edu
Poster Location: Zone C, Number 41
Mentor: Paolo Goffredo, MD
Bio: I am general surgery resident at the University of Minnesota interested in pursuing a career in colorectal surgery. My research interests are in colon cancer patient outcomes and surgical education.
Metachronous Colon Cancer Incidence after Endoscopic Resection of Adenomas with High-Grade Dysplasia
Authors: Weaver L, Boatman S, Kohn J, Mott S, Gaertner WB, Madoff RD, Melton GB, Shaukat A, Hassan I, Goffredo P
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Lindsay Welton, MD, BA | welto031@umn.edu
Poster Location: Zone C, Number 42
Mentor: Paolo Goffredo, MD
Surgical outcomes and patterns of care for early-stage rectal cancer in the United States
Authors: Welton LL, Kohn JF, Squillaro AI, Quick MH, Mott SL, Boatman SM, Troester AM, Jensen CC, Gaertner WB, Hassan I, Goffredo P
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Tara Rick, PhD | rickx045@umn.edu
Poster Location: Zone C, Number 43
Mentor: Anne Blaes, MD
Bio: Tara Rick, PhD has been a PA-C in oncology at the University of Minnesota for the last 17 years, with a clinical focus on breast cancer and cancer survivorship. Since 2023 she has a post-doctoral position working with Dr. Anne Blaes in cancer survivorship and is a member of the Masonic Cancer Center in the Screening, Prevention, Etiology, and Cancer Survivorship (SPECS) program.
UMN Breast Cancer Registry: expanding variables and opportunities for research
Authors: Rick TJ, Ramesh V, Jantschek N, Blaes A
Aurpita Shaha, PhD | shaha041@umn.edu
Poster Location: Zone A, Number 5
Mentor: Ningling Kang, PhD
CMTM6 promotes colorectal liver metastasis by controlling PM localization of Glut1 and glycolysis
Authors: Aurpita S., Yuanguo W., Xianghu W., Bing B. and Ningling K.
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Chinasa A Ufondu, BPharm | ufond002@umn.edu
Poster Location: Zone A, Number 6
Mentor: Julie Ostrander, PhD
Bio: I am a third year PhD student in the Molecular Pharmacology and Therapeutics Program. My research in the Ostrander lab focuses on investigating drivers of estrogen-induced lobular carcinoma.
Assessing the Effect of E-cadherin loss on ER activity in Human Mammary Epithelial Cell Models.
Authors: Ufondu CA, Musick M, Sikora MJ, Ostrander JH
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Jacque Lyman, BS | lyman076@umn.edu
Poster Location: Zone A, Number 7
Mentor: Scott Dehm, PhD
Bio: Jacque is a second year graduate student in the Molecular, Cellular, Developmental Biology and Genetics graduate program. Her research focuses on identifying genetic biomarkers in patients with Castration Resistant Prostate Cancer to inform treatment options and prognosis. During her graduate training, Jacque is also pursuing a Masters in Genetic Counseling to enhance patient care using research and cutting edge genetic tools.
Exploring Biomarkers in a Phase II Trial of Sacituzumab Govitecan in Advanced Prostate Cancer
Authors: Lyman J, Knutson TP, Sperger J, Yang R, Kyriakopolous C, Slovin S, Tagawa S, Lang JM, Dehm SM
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Megan Ludwig, PhD | mlludwig@umn.edu
Poster Location: Zone A, Number 8
Mentor: Justin M Drake, PhD
Bio: I completed my doctorate at the University of Michigan investigating mechanisms of resistance to EGFR-targeted therapy in head and neck cancer. I am now a postdoc in Dr. Justin M Drake's lab, using the proteome of extracellular vesicles to understand resistance to androgen-deprivation therapies in advanced prostate cancer.
Characterizing the landscape of extracellular vesicles from prostate cancer cell lines
Authors: Ludwig ML, Sychev Z, Day A, Bergom H, Hwang J, Drake JM
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Olivia Kuckhahn, BS | kanna131@umn.edu
Poster Location: Zone A, Number 9
Mentor: Kaylee Schwertfeger, Ph.D.
Bio: Olivia is a second-year Ph.D. student in the Molecular Pharmacology and Therapeutics program. She received her Bachelor of Science in Biochemistry, Cell, and Molecular Biology (BCMB) and Chemistry from Drake University in Des Moines, Iowa.
STAT5 in Tumor-Associated Macrophages Suppresses Invasion of Triple-Negative Breast Cancer Cells
Authors: Kuckhahn OK, Schwertfeger KL
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Samuel Pitzen, BA | pitze022@umn.edu
Poster Location: Zone A, Number 10
Mentor: Scott M Dehm, PhD
KLF5 drives double-negative prostate cancer through a mixed basal, club, and hillock cell identity
Authors: Pitzen SP, Qiu Y, Zhang W, Munro SA, Dehm SM
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Songyi Bae, PhD | sybae@umn.edu; tengs006@umn.edu
Poster Location: Zone A, Number 11
Mentor: Justin Drake, PhD
ASCL1-mediated Transcriptional Regulation of RET in Neuroendocrine Prostate Cancer
Authors: Bae SY, Tengse SB, VanDeusen HR, Dinh QC, Bergom HE, Day A, Boytim E, Baca SC, Xie Y, Long HW, Ellis L, Hwang JH, Drake JM
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Tingyuan Yang, MS | yang6906@umn.edu
Poster Location: Zone A, Number 12
Mentor: Ameeta Kelekar, PhD
Bcl-2 protein Noxa mediates both proliferative metabolism and apoptosis in human CD8T cells
Authors: Yang T, Sharma H, Webber B, Pennell C, and Kelekar A
Abdur Rahim, PhD | rahim032@umn.edu
Poster Location: Zone A, Number 1
Mentor: Natalia Tretyakova, PhD
The functional roles of Tet proteins in the development of lung cancer
Authors: Rahim A, Ruis B, Rajczewski A, Tretyakova Y
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Lucas da Silva, PhD | lucas334@umn.edu
Poster Location: Zone A, Number 2
Mentor: Leena Hilakivi-Clarke, PhD
Mechanisms of alpha-linolenic acid in preventing adverse cardiac events of letrozole in Zebrafish
Authors: Joas Locas da Silva, Luke Hoeppner, and Leena Hilakivi-Clarke
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Matthew Luedtke, PhD | lued0053@d.umn.edu
Poster Location: Zone A, Number 3
Mentor: Stephen Hecht, PhD
Metabolism of the Deuterium-Labelled Carcinogen N’-Nitrosonornicotine in Smokeless Tobacco Users
Authors: Luedtke MW, von Weymarn LB, Carlson ES, Gurvich VJ, Hatsukami DK, Hecht SS
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Mohammad Shameem, PhD | mshameem@umn.edu
Poster Location: Zone A, Number 4
Mentor: Fekadu Kassie, Ph.D.
Mitomet suppresses the survival of cancer stem-like cells derived from highly aggressive lung cancer
Authors: Shameem M, Bagherpoor AJ, Nakhi A, Dosa P, Georg G, Kassie F
Heidi Eschenbacher, PhD | hje@umn.edu
Poster Location: Zone C, Number 44
Mentor: Rahel Ghebre, MD, MPH
Bio: Heidi Eschenbacher, PhD is an evaluator and manager for diversity, equity, and inclusion efforts at the Masonic Cancer Center under the leadership and Direction of the Associate Director for DEI, Rahel Ghebre, MD, MPH. They work in collaboration with Cancer Research Training and Education Coordination Core (CRTEC) and Community Outreach and Engagement (COE)
How is MCC doing in representation of underrepresented populations?
Authors: Eschenbacher, HJ; Ghebre, RG; Pennell, C
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Hyunsoo Kim, PhD, MS | kimx0662@umn.edu
Poster Location: Zone C, Number 45
Mentor: Jinhua Wang, PhD
Bio: Dr. Hyunsoo Kim is a Bioinformatics Research Scientist in the Institute for Health Informatics and the Masonic Cancer Center, University of Minnesota. His research interests encompass the development of novel computational methodologies and quantitative analysis of biological health data to uncover new insights into molecular biology related to cancer and aging.
Investigating Senescence Signatures in Breast and Ovarian Cancer Tissues
Authors: Kim H, Winterhoff B, Niedernhofer L, Aliferis C, Wang J
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Jinhee Cha, MPH | cha00003@umn.edu
Poster Location: Zone C, Number 46
Mentor: Shannon Pergament, MPH, MSW & Pilar de la Parra
Bio: Jinhee Cha (he/him), MPH is a PHD student and a T32 Cancer Disparities pre-doctoral training fellow under the mentorship of Dr. Erin Marcotte, Shannon Pergament and Pilar de la Parra. His research interests are in policy, cancer health disparities and social determinants of health. His dissertation will be on the impacts of the Affordable Care Act on pediatric cancer disparities.
Community-based pediatric palliative care research in Somali, Hmong, and Latin American communities
Authors: Cha J, Pergament S, Parra DLP, Lee S, Ahmed A, Culhane PK, Batres R, Needle J
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Kate Honeyfield, BA | honey025@umn.edu
Poster Location: Zone C, Number 47
Mentor: Deanna Teoh MD, MS, FACS, FACOG
Bio: Kate is a research coordinator in the OBGYN department at the University of Minnesota.
Increasing HPV vaccination among survivors of childhood cancer: A Quality Improvement Initiative
Authors: Kate Honeyfield, Anja Dulin, Julia Gourde, Andrea Iverson, Katharine Lange, Helen Parsons, Rida Shaikh, Rachel Vogel, Lindsey Wanberg, Karim Sadak, Deanna Teoh
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Lindsey Mortensen, BS | morte303@umn.edu
Poster Location: Zone C, Number 48
Mentor: Lindsey Mortensen, BS
Bio: Lindsey is a third year medical student at the University of Minnesota, Twin Cities. Her interests range from cancer pathogenesis and treatments to systems based approaches to quality improvement in oncology care.
Operationalizing the electronic medical record to create head and neck cancer research databases
Authors: Dwyer AJ, Mortensen L, Wuertz BR, Ondrey FG
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Mariah Branson, BA | brans089@umn.edu
Poster Location: Zone C, Number 49
Mentor: Steven Fu, MD, MSCE
Bio: I am a research study coordinator for Dr. Steve Fu, MD, MSCE, at the Minneapolis VA Health Care System, and at the University of Minnesota, Twin Cities. The research studies I coordinate revolve around tobacco cessation, chronic pain, and I also coordinate Veteran engagement panels that provide feedback to Principal Investigators regarding upcoming grant submissions or ongoing research projects. All my projects have a focus on health equity and disparities in research and healthcare, which is an area of research I plan to continue working in for the rest of my research career.
Pilot: Veteran social support intervention for enhancing smoking treatment utilization and cessation
Authors: Branson M, Patten C, Brockman T, Hammett P, Nelson D, Danan E, Meis L, Fu S; Funding Information: Veteran Affairs Health Services Research & Development (VA HSR&D); Center for Care Delivery Outcomes Research (CCDOR)
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Monica Sauer, BS | sauer279@umn.edu
Poster Location: Zone C, Number 50
Mentor: Tanya Freedman, PhD
Lyn-mediated estrogen signaling in macrophages and monocytes
Authors: Monica L. Sauer and Tanya S. Freedman, PhD
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Roberto Alonso Matilla, PhD | alons075@umn.edu
Poster Location: Zone C, Number 51
Mentor: David J. Odde, PhD and Paolo P. Provenzano, PhD
Optimization of Therapeutic T cells Through Biophysical Modeling
Authors: Alonso-Matilla R, Provenzano PP, Odde DJ
Alexander McKeeken, MS, BS | mckee300@umn.edu
Poster Location: Zone B, Number 18
Mentor: Hai Dang Nguyen, Ph.D.
Bio: I am a Bioinformatics and Computational Biology Ph.D. student with experience in deep learning and database management and design. My current research focus is on big data analytics to uncover the impact of alternative splicing on myelodysplastic syndromes.
RNA-seq Pipeline for Identifying Alternative Splicing in U2AF1-mutant Myelodysplastic Syndromes
Authors: McKeeken AJ, Nguyen HD
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Courtney Labe, BA | Labe0105@umn.edu
Poster Location: Zone B, Number 19
Mentor: Jaime Modiano, VMD, PhD. Kelly Makielski, DVM, MS, DACVIM (SAIM)
Bio:
Investigation of exosome concentration as a potential biomarker for canine cancer
Authors: Labé CH, Wojtysiak MM, Lewellen M, Winter AL, Reid K, Myers EL, Modiano JF, Makielski KM
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Elisabet Ampudia Mesias, PhD | ampud001@umn.edu
Poster Location: Zone B, Number 20
Mentor: Okay Saydam, PhD
OTX2 Triggers Leptomeningeal Metastasis by Regulating the mTOR Signaling Pathway in Medulloblastoma
Authors: Ampudia Mesias E, Cameron CS, Anderson SM, Abrahante Lorens Juan E, Moertel CL, Odde DJ, and Saydam O.
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Gloria Baxter, PhD, MS | baxte258@umn.edu
Poster Location: Zone B, Number 21
Mentor: Louis Mansky, PhD
Defining a role for actin cytoskeleton regulation in retrovirus particle assembly and infectivity
Authors: Baxter GC, Hanson, HM, Mansky LM
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Heather Hanson, PhD
Poster Location: Zone B, Number 22
Mentor: Louis Mansky, PhD
Actin cytoskeleton dynamics regulates human retrovirus particle assembly and infectivity
Authors: Heather M Hanson, Gloria Baxter, Louis M Mansky
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Joshua Schwanke, BS | schw2466@umn.edu
Poster Location: Zone B, Number 23
Mentor: Ajay Prakash, MD PhD
A randomized placebo-controlled trial of probiotic supplementation during adjuvant chemotherapy
Authors: Schwanke JD, AbuAyed R, Prinzment A, Straka R, Subramanian S, Prakash A
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Kacey Bui, BS | kgbui@umn.edu
Poster Location: Zone B, Number 24
Mentor: Hai Dang Nguyen, PhD; Jakub Tolar, MD, PhD
Bio: Kacey matriculated into the UMN Medical Scientist Training Program (MSTP) in 2018 and is currently a 4th year PhD candidate in the Molecular, Cellular, Developmental Biology & Genetics graduate program. Her research and clinical interests are focused on pediatric genetic diseases, blistering disorders, wound healing and cancer development.
HMGB1 expression affects inflammatory signaling in human keratinocytes
Authors: Bui KG, Nguyen HD, Bielinsky AK, Tolar J.
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Travis Gates, BA | gates173@umn.edu
Poster Location: Zone B, Number 25
Mentor: Subree Subramanian, MS, PhD
Allogeneic Tumor Extracellular Vesicles Stimulate CD8 T Cell Response in Colorectal Cancer
Authors: Gates TJ, Wangmo D, Zhao X, Subramanian S
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William Arndt, BS| arndt255@umn.edu
Poster Location: Zone B, Number 26
Mentor: Louis Mansky, PhD
Insights into Immature Particle Morphology via Cryo-EM/ET Analysis of HTLV-1 Capsid
Authors: Arndt WG, Talledge N, Yang H, Zhang W, Mansky LM
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Ya-Chu Chang, PhD | chan1285@umn.edu
Poster Location: Zone B, Number 27
Mentor: Hai Dang Nguyen, PhD
A potential role of alternative splicing control in DNA damage response.
Authors: Chang YC and Nguyen HD
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Yingbo Huang, MS | huan1958@umn.edu
Poster Location: Zone B, Number 28
Mentor: R.Stephanie Huang, PhD
Bio: My name is Yingbo Huang, I am a PhD student in the Experimental and Clinical Pharmacology program at the U. I work in Stephanie Huang's group, studying the genetic mechanism of sex dimorphism in cancer.
Identification of sex-specific molecular features in glioma transcriptome
Authors: Yingbo Huang, Yuting Shan, Weijie Zhang, Christina Printzis, Lorenzo Pesce, Barbara Elaine Stranger, R. Stephanie Huang
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Yoonkyu Lee, MS, BS | leex5085@umn.edu
Poster Location: Zone B, Number 29
Mentor: Zohar Sachs, MD, PhD
Machine Learning Analysis Reveals TP53 Mutant-like AML With Wild Type TP53 And Poor Prognosis
Authors: Lee Y, Baughn LB, Myers CL, Sachs Z
Anders Matson, BS | matso198@umn.edu
Poster Location: Zone B, Number 30
Mentor: Bruce Walcheck, PhD
Bio: My name is Anders Matson, and I am a graduate student in Dr. Bruce Walcheck’s lab. I am studying how to improve NK cell-based cancer immunotherapies by blocking ADAM17’s function with the mAB Medi-1.
Inhibition of ADAM17 enhances NK cell proliferation by IL-15 through increased CD137 co-stimulation
Authors: Matson AW, Hullsiek RH, Dixon KJ, Friess RR, Wang SP, Phung G, Khaw M, Hart G, Dick JK, Felices M, Wu J, Miller JS, Walcheck B.
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Lynn Heltemes Harris, PhD | harr0905@umn.edu
Poster Location: Zone B, Number 31
Mentor: Michael Farrar
Bio: I am Senior Research Scientist in the Farrar Lab in the Center for Immunology. My research is centered around understanding what B cell developmental factors play a role in leukemia induction. Outside of the laboratory I love to spend time with her husband (Jack) and twins (Erin and JJ), biking, spending time at the lake and enjoying the outdoors.
HISTONE ACETYLTRANSFERASES IN B CELL DEVELOPMENT AND TRANSFORMATION
Authors: Lynn M. Heltemes-Harris, Xunhe Li, Robin D. Lee, Taylor L. Maiers and Michael A. Farrar
Julia Kohn, MD
Poster Location: Zone B, Number 32
Mentor: Elliot Arsoniadis, MD, PhD
Bio: Dr. Kohn is a 5th-year resident in the Department of Surgery. Her research and professional interests include colorectal surgery, especially cancer outcomes and LGBT healthcare.
Save the Bottoms!!! at Pride: a novel community event-based anal cancer screening protocol
Authors: Kohn JF, Vera K, Alch S, Botsford C, Wendlund Z, O'Donnell J, Melton GB, Arsoniadis EG
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Maria Martell, BS | marte353@umn.edu
Poster Location: Zone C, Number 33
Mentor: Christopher Staley, PhD
Bio: I graduated from the University of Minnesota in 2022 with a major in biology and a minor in public health. I currently work as a Researcher II in Dr. Christopher Staley's laboratory, where I use computational techniques to investigate changes in human microbial ecology as it relates to a variety of diseases, including colorectal cancer. I plan to apply to medical school in the future.
Kras Gene Exacerbates Microbial Dysbiosis and Tumor Aggressiveness in Murine Model of Colon Cancer
Authors: Maria Martell, Mahendra Rathore, Nirupa Ganesan, Khashayarsha Khazaie, Ph.D., Christopher Staley, Ph.D.
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Matthew Dietz, BA | dietz177@umn.edu
Poster Location: Zone C, Number 34
Mentor: Christopher Staley, PhD
Bio: Matthew is currently pursuing a PhD in Dr. Staley's lab through the Bioinformatics and Computational Biology (BICB) program. He completed his undergraduate degree in Biology at Gustavus Adolphus College in 2019 and is now studying the gut microbiome and its role in disease, with a focus on colorectal cancer.
Quorum Quenching Decreases Metastatic Rate in a Colorectal Cancer AKPS Organoid Mode
Authors: Dietz Matthew, Staley Christopher, Gates Travis, Subramanian Subree, Elias Mikael
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Rui Cao, PhD | cao00128@umn.edu
Poster Location: Zone C, Number 35
Mentor: Tianzhong Yang, PhD
Bio: Rui is a PhD candidate in biostatistics at the University of Minnesota. His research is mainly focused on post-GWAS studies and genomic marker prediction.
Subset scanning for multi-trait analysis using GWAS summary statistics
Authors: Cao R, Olawsky E, McFowland E, Marcotte E, Spector L, Yang T.
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Sam Greenwald, MS | greens@umn.edu
Poster Location: Zone C, Number 36
Mentor: Helen Parsons, PhD, MPH
Bio: Sam Greenwald received his MS in Health Services Research, Policy & Administration from the University of Minnesota School of Public Health. He now works as a Senior Research Associate in the Division of Health Policy and Management.
Financial Outcomes after a Cancer Diagnosis: Results from a Survey of Cancer Survivors in MN
Authors: Greenwald SJ, Zumbrunnen ARG, Yokanovich L, Kourelis R, Parsons HM
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Shuo Wang, PhD, MPH | wang8310@umn.edu
Poster Location: Zone C, Number 37
Mentor: Anna Prizment, PhD MPH Anne Blaes, MD
Senescence-associated secretory phenotype aging index and all-cause mortality in cancer survivors
Authors: Wang S, Rao Z, Blaes AH, Coresh J, Joshu C, Pankow JS, Thyagarajan B, Ganz P, Platz EA, Guan W, Prizment A
Aoibhin Sheedy, MS, BME | asheedy@umn.edu
Poster Location: Zone C, Number 38
Mentor: Aoibhín Sheedy, MSc, BME
Bio: An early career biomedical engineer who is currently completing a PhD in the development of a cell immunotherapy and delivery device to treat ovarian cancer in the University of Galway. She was awarded a Fulbright Scholarship to carry out a year at the University of Minnesota.
Towards a replenishable intraperitoneal delivery device of immunotherapies to treat ovarian cancer
Authors: Sheedy, A.M., Shetty. M, Bendzick. L, Selleck. C, Ward. N, Trask. L, Duffy. G.P., Geller. M.A., Miller. J.S., Dolan, E.B., Felices, M
Abhishek Kulkarni, MS, BS | kulka224@umn.edu
Poster Location: Zone A, Number 7
Mentor: Carston R. Wagner, PhD
Bio: I am a 5th year Ph.D. candidate in Dr. Carston R. Wagner's laboratory in the Department of Medicinal Chemistry. My research involves the design and development of bispecific protein nanorings for the selective redirection of human T and NK-cells to combat solid tumors.
Protease-Activatable Nanorings for Selective Redirection of Immune Cells to Combat Solid Tumors
Authors: Kulkarni AS, Paul D, Ligori K, Rodriguez F, Rozumalski L, Friess R, Walcheck B, Wagner CR
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Alexis Elfstrum, BS | elfst022@umn.edu
Poster Location: Zone A, Number 8
Mentor: Kaylee Schwertfeger, PhD
Bio: Alexis is a 5th year MICaB graduate student in the lab of Dr. Kaylee Schwertfeger.
LYVE-1+ macrophages modulate the extracellular matrix and contribute to mammary tumor growth
Authors: Elfstrum AK, Rumahorbo AH, Nelson EV, McCluskey BM, Schwertfeger KL
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Angela Spartz, PhD | spar0019@umn.edu
Poster Location: Zone A, Number 9
Mentor: Carol A. Lange, PhD and Dorraya El-Ashry, PhD
CAFs support ER+ breast cancer cells via CAF-secreted FGF2 signaling to PR activation
Authors: Spartz AK, Diep CH, El-Ashry D*, Lange CA*
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Debasmita Paul, MS, BS | paul1229@umn.edu
Poster Location: Zone A, Number 10
Mentor: Dr. Carston R. Wagner, PhD
Bio: I was interested in using chemistry as a tool to investigate into biological systems. After earning MS in chemistry, I pursued my interest and am currently working on a project involving immunotherapy. Proteins fascinate me and I am learning the art of protein expression, characterization and application as tools to stimulate cells.
Investigating nanobody appended CSANs on targeting immune cells to tumor cells
Authors: Debasmita Paul, Abhishek Kulkarni, Dr. Carston R. Wagner
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Gabrianne Larson, BS | lars5893@umn.edu
Poster Location: Zone A, Number 11
Mentor: Justin Drake, PhD
Bio: Gabrianne Larson is a recent graduate of the University of Minnesota-Twin Cities with a B.S. in Chemistry. She has been working with Dr. Justin Drake since 2019 and her most recent project involves quantifying androgen receptor splice variants in prostate cancer.
Androgen Receptor Splice Variant Protein Quantification using Targeted MS in Prostate Cancer Models
Authors: Larson G, Sychev ZE, Plymate SR, Corey E, Balk SP, Dehm SM, Drake JM
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Hongrong Zhang, MS | Zhan6978@umn.edu
Poster Location: Zone A, Number 12
Mentor: Paolo Provenzano, PhD
Stroma and cell engineering strategies to enhance cytotoxic T cell migration in pancreatic cancer
Authors: Zhang H, Qian G, Chen Z, Odde DJ, Moriarity BS, Stromnes IM, Provenzano PP
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Jennifer Tuokkola, BS | tuokk002@umn.edu
Poster Location: Zone A, Number 13
Mentor: Kaylee Schwertfeger, PhD
Bio: Jennifer graduated from Ohio State in 2020 with a degree in Biochemistry and joined the Molecular Pharmacology and Therapeutics graduate program. She joined Dr. Schwertfeger's lab in 2021 where she studies signaling and metabolic pathways in breast cancer.
FGFR-Mediated Dysregulation of Cholesterol Homeostasis Contributes to Breast Cancer Metastasis
Authors: Tuokkola JE, Reese LE, Schwertfeger KL
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Kiel Tietz, PhD | tietz025@umn.edu
Poster Location: Zone A, Number 14
Mentor: Scott Dehm, PhD
Bio: Postdoctoral researcher interested in AR dependent and AR independent mechanisms that drive prostate cancer development.
Alternative Polyadenylation as a Therapeutic Vulnerability in Prostate Cancer
Authors: Tietz KT, Braedan MM, Conor MR, Yingming L, Munro SA, and Dehm SM
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Natasha Roman Ortiz, BS | roman449@umn.edu
Poster Location: Zone A, Number 15
Mentor: Julie Ostrander, PhD
Targeting breast cancer stem cells with oncolytic virus
Authors: Roman Ortiz N, Davydova J, Danthi P, Ostrander J
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Radha Manohar Kapgate, BS | kapga001@umn.edu
Poster Location: Zone A, Number 16
Mentor: Scott Dehm, PhD
Testing drug vulnerabilities in prostate cancer cells harboring AR gene rearrangements
Authors: Kapgate R, Zhang W, Huang SR, Dehm SM
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Sachi Tengse, BTech
Poster Location: Zone B, Number 17
Mentor: Justin Drake, PhD
Bio: Sachi is a Master's student in the Molecular Pharmacology and Therapeutics (MPaT) Graduate Program. She received her B.Tech in Biotechnology from Manipal Institute of Technology, India in 2021. She is currently working on RET kinase and ASCL1 in neuroendocrine prostate cancer in the Drake Lab.
Non-enzymatic function of RET kinase in neuroendocrine prostate cancer
Authors: Sachi B Tengse, Song Yi Bae, Quynh Chau Dinh, Rayhan Biswas, Laura Hirsch, Farzana Kabir, Daniel A. Harki, Justin M Drake
Eleanore Hansen, MS | hans6999@umn.edu
Poster Location: Zone A, Number 1
Mentor: Irina Stepanov, PhD
Bio: I am a 3rd year PhD student in the SPH Division of Environmental Health Science in the Toxicology track. I have a MS in Food Science with an emphasis on food safety. My research interests are in food safety, the roles of commercial tobacco products in carcinogenesis, and regulatory toxicology.
Associations Between Sugar Levels in Tobacco Filler and Harmful Constituents in Cigarette Smoke
Authors: Hansen E, Yershova K, Pauls C, Luo X, Stepanov I
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Erik Moran, MS | moran598@umn.edu
Poster Location: Zone A, Number 2
Mentor: Natalia Tretyakova, PhD
Bio: I am a 4th year graduate student studying the formation and effects of protein and DNA adducts that result from both internal and external exposures. The goal of my research is to understand the biological mechanisms connecting the formation of these adducts with disease such as lung cancer.
Profiling the Hemoglobin adductome of smokers and non-smokers by targeted LC/MS analysis
Authors: Moran EJ, Hurben AK, Gann J, Rajczewski A, O'Donnell A, Boysen B, Tretyakova NY
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Holly Den Hartog | denha038@umn.edu
Poster Location: Zone A, Number 3
Mentor: Natalia Tretyakova, PhD
Bio: Holly Den Hartog is a fourth year undergraduate student majoring in chemistry and minoring in biochemistry. Her work in the Tretyakova lab is focused on the organic synthesis of cigarette-smoke induced DNA adducts. After graduating in the spring, she plans on attending graduate school in chemical biology.
Progress toward the syntheses of a nucleoside phosphoramidite and triphosphate of DEB-FAPy-dG
Authors: Den Hartog HI, Kumar HV, Park SY, Legaspi JA, Gutiérrez S, Lorentz C, Tretyakova NY
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Mei-Kuen Tang, MS | tangx419@umn.edu
Poster Location: Zone A, Number 4
Mentor: Stepehen Hecht, PhD
Bio: Mei-Kuen is a 2nd year PhD student from the Graduate Program in Molecular Pharmacology and Therapeutics, University of Minnesota, Minneapolis. Her graduate work is under the supervision of Dr. Stephen Hecht.
13C Labelled Burley Tobacco – A Potential Tool for DNA Adductomics Studies of Cigarette Smokers
Authors: Tang MK, Li Y, Cohen JD, Hegeman AD, Peters CP, Carmella SG, and Hecht SS
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Michael Sausen, BS | sause023@umn.edu
Poster Location: Zone A, Number 5
Mentor: Silvia Balbo, PhD
DNA Adductomics to Characterize Acetaldehyde-Induced DNA Damage
Authors: Sausen MC, Callegari M, Maertens LA, Villalta PW, Balbo S
Andrew Frederickson, BS | frede598@umn.edu
Poster Location: Zone C, Number 39
Mentor: Samira Azarin, PhD; Alptekin Aksan, PhD
Bio: I am a fourth-year PhD student at the University of Minnesota advised by Alptekin Aksan (ME) and Samira Azarin (CEMS). My research utilizes biomaterials to investigate the regulatory mechanisms of cellular dormancy and chemoresistance in ovarian cancer. I am also interested in elucidating the interactions between dormant cancer cells and the immune system in order to design more efficacious immunotherapies for metastatic disease.
Utilizing a Novel Biomaterial to Examine Dormancy and Therapy Resistance in Ovarian Cancer
Authors: Frederickson A, Lam T, Aksan A, Azarin SM
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Caitlin Lichtenfels, BS, PhD | licht189@umn.edu
Poster Location: Zone C, Number 40
Farnesylated Chemically Self Assembled Nanorings for Chemotherapeutic Drug Delivery
Authors: Lichtenfels, CB, Wang, Y, Distefano, MD, Wagner, CR
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Chris Basting, MS, BS | bast0159@umn.edu
Poster Location: Zone C, Number 41
Mentor: Nichole Klatt, PhD
Bio: Chris Basting is a researcher and lab manager in the lab of Dr. Nichole Klatt, where his research primarily focuses on uncovering host-microbe interactions that contribute to COVID-19 and HIV infection. He recently finished his Masters degree in the Bioinformatics and Computational Biology program at the UofM and is now working on his PhD.
Immune activation is associated with specific gut microbes in people living with HIV
Authors: Basting C, Escandon K, Anderson J, Cromarty R, Schroeder T, Velez A, Wieking G, Reichel J, Guerrero C,4, Briceño O, Torres-Ruiz F, Avila S, Salgado G, Schacker T, Klatt N
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Jianxun Lei, PhD | leixx007@umn.edu
Poster Location: Zone C, Number 42
Mentor: David A Potter
B7-H3 and B7-H4 are Regulated by (±)14,15-EET Mediated N-Glycosylation in ER+HER2- Mammary Cancer
Authors: Jianxun Lei, Zhijun Guo, Adam Bass, Christine Cannon, Joshua McCarra, Brenda Koniar, Craig M. Flory, Beverly Norris, Robert J. Schumacher, Swaathi Jayaraman, John Hawse, Emmanuel S. Antonarakis, Emanuel F. Petricoin, Julia Wulfkuhle, Robert D. Cardiff, Victor Garcia, John R. Falck, Dafydd G. Thomas, Elizabeth A. Ambrose, Gunda I. Georg, Kaylee L. Schwertfeger, Michael A. Farrar, Matthew P. Goetz, and David A. Potter.
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Karina Deniz, BS | kdeniz@umn.edu
Poster Location: Zone C, Number 43
Mentor: Emil Lou, MD PhD
Bio: I am Karina Deniz with a bachelor's degree in biomedical engineering. I am currently researching tunneling nanotubes in Dr. Emil Lou's lab for the last two years.
Tumor-Treating Fields Suppress Tunneling Nanotube Conduits Between Ovarian Cancer Cells
Authors: Karina Deniz*, Sanyukta Padmanabhan*, Katherine Ladner, Phillip Wong, Akshat Sarkari, Clifford J Steer, Emil Lou
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Kristin Boman, MPH | kboman@umn.edu
Poster Location: Zone C, Number 44
Fostering a Climate of Curiosity in Primary Care by Growing a PBRN: A Process Description
Authors: Boman K, Botsford C, Alch S, Bengtson J, Adam P, Chambers R, Zineldin L, Bork Nichols L, Beebe T, Melton GM, Berge JM
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Michael Luo | luo00302@umn.edu
Poster Location: Zone C, Number 45
Mentor: Aimee Merino, MD, PhD
Novel Targeting of MICA/B Enhances NK Cell Therapy Against Multiple Myeloma
Authors: Luo M, Hamsher H, Davis Z, Bjordahl R, Goulding B, Valamehr B, Miller JS, Merino A
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Qianyun Luo, BS | luo00336@umn.edu
Poster Location: Zone C, Number 46
Mentor: David Brauer, MD, MPHS
Impact of Income and Education in Survival Models for Patients with Resected Pancreas Cancer in NCDB
Authors: Luo Q, LaRocca CJ, Ankeny JS, Jensen EH, Marmor S, Brauer DG
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Sacha Robert, PhD | srobert@umn.edu
Poster Location: Zone C, Number 47
Mentor: Julia Davydova, MD, PhD
Targeting Chemoresistant Breast Cancer Stem Cells with Oncolytic Adenovirus: A Promising Approach.
Authors: Robert S, Roman NI, Jacobsen K, Romanenko M, Inoko K, Wilber S, LaRocca CJ, Ostrander JH, Davydova J.
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Virginia Hsiao, BA | hsiao037@umn.edu
Poster Location: Zone C, Number 48
Mentor: Jeffrey Miller, MD
Bio: Virginia Hsiao is a second year medical student at the University of Minnesota Medical School. She completed her undergraduate degree in Molecular Cell Biology at UC Berkeley. She looks forward to becoming a future physician, aiming to alleviate patients’ physical, emotional, and social suffering and aspiring to be part of the effort to advance medicine through research to provide patients and bring clinical innovations to patients with the greatest needs.
Tri-specific Killer Engagers Overcome Dexamethasone-Mediated Immunosuppression of NK Cells
Authors: Hsiao V, Wang H, Cromarty R, Davis Z, Miller JS
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Yun You, PhD | yyou@umn.edu
Poster Location: Zone C, Number 49
Mentor: Timothy Hallstrom, Ph. D.
Mouse Genetics Laboratory (MGL)
Authors: Yun Y,
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Zhenya Ni, PhD | nixxx012@umn.edu
Poster Location: Zone C, Number 50
Mentor: Melissa Geller, MD
A Tri-specific Killer Engager of PD-L1 Enhances NK cell immune function against Ovarian Cancer
Authors: Zhenya Ni, Erin Wesley, Laura Benzick, Carly Celleck, Martin Felices, Jeffrey S. Miller, Melissa A. Geller
Adam Cook | cook0663@umn.edu
Poster Location: Zone A, Number 15
Mentor: Kelly Makielski
Bio: My names Adam Cook and I'm currently a undergraduate student working towards a degree in genetics and cell development whilst working within the Modiano lab. My work centers around defining canine osteosarcoma immune response. This is the first project I've undertaken with hopefully more to come soon!
Defining the effects of oncolytic virotherapy on T-cell clonal diversity in canine osteosarcoma
Authors: Cook AM, Parys M, Naik S, Russell SJ, Modiano JF, Makielski KM
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Ajibola Opakunle, PhD | opaku003@umn.edu
Poster Location: Zone A, Number 16
Mentor: Stephanie Huang, PhD
Bio: My name is Aji Opakunle and I am a third-year Ph.D. student in Molecular Pharmacology and Therapeutics, conducting research under the guidance of Dr. R. Stephanie Huang at the University of Minnesota-TC. My research focuses on exploring the genetic causes of sexual dimorphism in cancer using statistical approaches and computational tools.
Deciphering the Genetic Mechanism of Sex Differences within Multiple Myeloma
Authors: Opakunle AA, Huang RS
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Caitlyn Callaghan, BS | calla542@umn.edu
Poster Location: Zone B, Number 17
Mentor: Jaime Modiano, VMD, PhD
Bio: Caitlyn Callaghan is a third-year student at the University of Minnesota College of Veterinary Medicine. She is interested in specializing in medical oncology after receiving her Doctorate of Veterinary Medicine.
The Immune and Molecular Landscape of Canine Osteosarcoma
Authors: Callaghan CM, Burt LE, Wojtysiak MM, Labé CH, Moore M, Murugan P, Macchietto M, Cheng E, Largaespada DA, Borgatti A, Henson MS, Feiock C, Chehadeh A, Reid K, Winter AL, Pracht S, Bergsrud K, Bauer C, Mantovani L, Wietgrefe E, Bruess A, Weigel BJ, Greengard E, Makielski KM, Modiano JF, Sarver AL, Medland JE.
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Huixin Yang, PhD, DVM | yang5928@umn.edu
Poster Location: Zone B, Number 18
Mentor: Louis Mansky, PhD
Bio: I am a molecular virologist with 6 years experience in structure and function studies of human retrovirus particle assembly and morphology.
Identification of determinants in HTLV-1 CA-CTD that are critical for virus particle assembly
Authors: Yang H, Arndt WG, Zhang W, Mansky LM
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Meagan Wojtysiak, BS | wojty007@umn.edu
Poster Location: Zone B, Number 19
Mentor: Kelly Makielski, DVM, MS, DACVIM (SAIM) and Jaime Modiano, VMD, PhD
Bio: Meagan grew up in northern Minnesota, then traded the Twin Ports for the Twin Cities after obtaining her Bachelor of Science in biology. She is a second-year DVM student and her professional interests primarily lie in small animal medicine. This summer, Meagan had the opportunity to explore research in the Veterinary Summer Scholars program developing an interest in comparative oncology.
Optimizing plasma exosome enrichment for the early detection of canine osteosarcoma
Authors: Wojtysiak MM, Labé CH, Lewellen M, Myers EL, Winter A, Reid K, Modiano JF, Makielski KM
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Mizuho Sato-Dahlman, PhD | satom@umn.edu
Poster Location: Zone B, Number 20
Mentor: Masato Yamamoto, M.D., Ph.D.
Engineering the cancer-targeted oncolytic adenovirus with fiber modification
Authors: Sato-Dahlman, M., Hajeri P., Roach R., Jacobsen K., Nakamura N.,, and Yamamoto M.
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Nuttavut Sumransub, MD | sumra009@umn.edu
Poster Location: Zone B, Number 21
Mentor: Zohar Sachs, MD, PhD
Bio: Current Hematology and Medical Oncology fellow at University of Minnesota. Main research focus in malignant hematology and immune reconstitution after bone marrow transplantation and cellular therapy.
TP53-Mutated Acute Myeloid Leukemia Patients Treated with Intensive Therapies have Superior Outcomes
Authors: Sumransub N, Steinwand GK, Lee Y, Cao Q, Allred JR, Ramesh V, Myers C, Sachs Z
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Travis Gates, BA | gates173@umn.edu
Poster Location: Zone B, Number 23
Mentor: Subree Subramanian, MS, PhD
Targeting LAT1 for Metabolic Intervention in Colorectal Cancer
Authors: Gates TJ, Wangmo D, Yuan C, Zhao X, Subramanian S
Abbey Knight | knigh530@umn.edu
Poster Location: Zone B, Number 24
Mentor: Lindsey Sloan, MD PhD
Bio: My name is Abbey Knight. I am an undergraduate student majoring in public health and psychology at the University of Minnesota. I have been working to develop this risk factor assessment tool for patients with glioblastoma with Dr. Sloan to build my research skills.
Developing a Clinical Tool to Identify Potential Risk Factors of Glioblastoma in Minnesotans
Authors: Knight A, Wieworka J, Golden L, Sando N, Terezakis SA, Williams L, Sloan L
Can Zhang, BS | zhan8639@umn.edu
Poster Location: Zone B, Number 25
Mentor: Xianghua Luo, PhD
Bio: Can Zhang is a second-year MS student in Biostatistics, School of Public Health, currently mentored by Dr. Xianghua Luo, a professor in the MCC Biostatistics Shared Resources, in researching Bayesian measurement error models with applications in tobacco research. A preliminary work of this research won him the Audience Favorite Award during the Division of Biostatistics 2023 Student Poster Competition. Can harbors a deep passion for statistical method development and applications in cancer-related research and aspires to further his study with a PhD in Biostatistics.
Bayesian Measurement Error Model: Assessing Cigarette Filter Ventilation's Impact on Biomarkers
Authors: Zhang C, Chu H, Paudel N, Stepanov I, Carroll D, Yershova K, Koopmeiners J, Donny EC, Hatsukami DK, Luo X.
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Courtney Sarkin, MBE | sarki052@umn.edu
Poster Location: Zone B, Number 26
Mentor: David Haynes, PhD
Bio: Courtney is a PhD candidate in Health Services Research, Policy, and Administration in the Division of Health Policy & Management at the University of Minnesota School of Public Health. Her dissertation examines how lesbian, bisexual and queer women's breast cancer screening usage is influenced by manifestations of structural oppression within the healthcare system.
ConnectedNest: Addressing Social Determinants of Health Among Cancer Survivors
Authors: Sarkin CA, Osegueda E, Trempe E
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Heather Nelson, PhD, MPH | hhnelson@umn.edu
Poster Location: Zone B, Number 27
New findings from the 10,000 Families Study
Authors: Nelson, H, Peterson, L, Huset, C, Stapelton, H, Hickle, A, Wilcox, C, Leonhardi, R, Lavallee, J Zhang, L, Poynter, J.
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Ibrahim Abdelgawad, BS | Abdel217@umn.edu
Poster Location: Zone B, Number 28
Mentor: Beshay Zordoky, MS, PHD
Cardiac Proteomics Analysis Reveals Sex Differences in Delayed Doxorubicin-induced Cardiotoxicity
Authors: Abdelgawad IA, George B, Grant MKO, Huang Y, Shan Y, Huang RS, Zordoky BN
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Lynn Tanner, MS | tanne240@umn.edu
Poster Location: Zone B, Number 29
Mentor: Diane Treat-Jacobson PhD, RN
Bio: Lynn Tanner, PT is a doctoral candidate in the School of Nursing. She is also the Scientific Director of Physical Medicine and Rehabilitation at Children's Minnesota. She conducts research on physical function impairments and interventions in children with cancer.
Physical Activity Influences in Survivors of Pediatric Cancer
Authors: Tanner LR, Turcotte LM, Marquard JL, Hooke MC, Tucker CA, Schorr EN, Treat-Jacobson D
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Maggie Chiu, BS | chiu0083@umn.edu
Poster Location: Zone B, Number 30
Mentor: Paolo P. Provenzano, PhD & David K. Wood, PhD
Bio: Maggie is a graduate research assistant in the Biomedical Engineering Department of the College of Engineering and Sciences pursuing her PhD. She completed her BS in 2020 at the University of California, Riverside, having conducted undergraduate research studying epithelial-stromal crosstalk in the gut microenvironment in the context of regenerative tissue engineering. Her current project interweaves biomedical engineering, microfluidic device generation, and cancer research to study cancer dormancy.
Development of a High-Throughput Cost-Effective In Vitro Model of Metastatic Breast Cancer Dormancy
Authors: Chiu M, Schwertfeger K, Wood DK, Provenzano PP
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Majid Farhadloo, PhD | farha043@umn.edu
Poster Location: Zone B, Number 31
Mentor: Shashi Shekhar, PhD
Towards A Spatially-Explainable Classifier for Analyzing Oncology Cellular Maps
Authors: Majid Farhadloo∗, Svetomir N. Markovic**, and Shashi Shekhar*
*Dept. of Oncology, Mayo Clinic, USA
**Dept. of Computer Science and Engineering, University of Minnesota
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Mary Raphel Daniel, PhD | dani0947@umn.edu
Poster Location: Zone B, Number 32
Mentor: Beshay Zordoky, MSc, PhD
Psychosocial stress exacerbates doxorubicin- induced cardiotoxicity in adult mice.
Authors: Daniel MR, Grant MKO, Razzoli M, Bartolomucci A, Zordoky BN
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Mohamed Dabour, MS, BS
Poster Location: Zone C, Number 33
Mentor: Beshay Zordoky, PhD
Canagliflozin mitigates carfilzomib-induced endothelial apoptosis via an AMPK-dependent pathway
Authors: Dabour MS, Abdelgawad IY, Grant MK, El-Sawaf ES, Zordoky BN
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Sarah Bennis, MPH | benni030@umn.edu
Poster Location: Zone C, Number 34
Utilization of anal cytology screening among sexual and gender minority populations in Pennsylvania
Authors: Bennis SL, Arsoniadis E, Wheldon CW
Colette Rogers, PhD | roger688@umn.edu
Poster Location: Zone C, Number 35
Mentor: Branden Moriarity, PhD
Bio: Dr. Colette Rogers is a postdoc in Drs. Moriarity and Webber's laboratories investigating gene therapy for Fanconi anemia, an inherited cancer predisposition disorder.
In vivo correction of genetically humanized Fanconi anemia mutations using digital base editing
Authors: Rogers CB, Peterson JP, Webber BM, and Moriarity BS
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Jacob Bridge, BS | bridg245@umn.edu
Poster Location: Zone C, Number 36
Mentor: Beau Webber, PhD
Bio: Jacob is a first year graduate student in the MCDB&G program, with a background in engineering immune cells for genetic disease treatment and cancer immunotherapy. He primarily focuses on gamma delta T cells, developing strategies to enhance their innate anti-tumor activity. Jacob has presented his research at several national conferences, including ASGCT 2023, and is currently writing a first author paper on the topic.
Non-virally engineered polyclonal gamma delta T cells exhibit potent anti-tumor activity in vivo
Authors: Bridge JE, Claudio-Vazquez P, Wenthe SJ, Krueger JB, Moriarity BS, Webber BR
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Ross Cromarty, PhD | rcromart@umn.edu
Poster Location: Zone C, Number 37
Mentor: Zachary Davis, PhD
Bio: Obtained my PhD from the University of KwaZulu Natal in South Africa, while working as a junior researcher at CAPRISA, exploring how TLR mediated inflammation and anti-inflammatory drugs influenced HIV infections rates. Received Fogarty training funding to spend 3 months research time at Northwestern University. Moved to the USA in 2020 as a Postdoc, now working on NK cell-mediated strategies to combat HIV.
A gp120 targeting TriKE harnesses NK cell mediated ADCC to kill reactivated HIV
Authors: Cromarty R, Soignier Y, Wang H, Walker J, Tuininga K, Zhang B, Hinderlie P, Schacker T, Miller J, Davis Z
Atef Ali, BS | alixx830@umn.edu
Poster Location: Zone A, Number 4
Mentor: Justin Hwang, PhD
Bio: Atef Ali is a bioinformatician in the Hwang Lab at the UMN Medical School in the Hematology, Oncology, and Transplantation Division. He graduated with a Bachelor's of Science in Mathematics with a focus on Computer Science and Statistics from the UMN College of Science and Engineering. Atef's research interests involve applying machine learning and large scale statistical and data analysis techniques to analyze -omics based data.
Computational Characterization of Oncogenic Transcriptomic Factors in Sarcomatoid RCC
Authors: Ali A, Semaan K, Bergom HE, Boytim E, Day A, Baca S, Hwang JH
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Conor Miller | mill9139@umn.edu
Poster Location: Zone A, Number 5
Mentor: Scott Dehm, PhD
AR mRNA Alternative Polyadenylation in Prostate Cancer
Authors: Miller CR, Tietz KT, and Dehm SM
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Courtney Baar, BS | baarx012@umn.edu
Poster Location: Zone A, Number 6
Mentor: Deepali Sachdev, PhD
Bio: I graduated from the University of MN in May 2020 and currently am a researcher in the Sachdev lab. I have been working on developing models to test effect of immunotherapeutic drugs and cyclin dependent kinases on growth of breast cancers. I am interested in attending graduate school in the future.
IGF1R and IR-A specific targeting of hormone receptor positive breast cancer with immune destruction
Authors: Baar CS, Chiu E, Johnson IR, Soignier Y, Kodal B, Miller JS, Felices M, Sachdev D
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Guhan Qian, MS
Poster Location: Zone A, Number 7
Mentor: Paolo Provenzano, PhD
Uncover the hidden immunosuppressive landscape in pancreatic ductal adenocarcinoma
Authors: Qian G, Zhang H, Provenzano PP
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Jocelyn Baquier, BS | jbaquier@umn.edu
Poster Location: Zone A, Number 8
Mentor: Carol A Lange, PhD
Modulation of progesterone signaling by BRCA1 depletion in advanced ovarian cancer cell models
Authors: Baquier J, Gillis NE, Mauro LJ, and Lange CA
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José Valentín López, BS | valen489@umn.edu
Poster Location: Zone A, Number 9
Mentor: Scott Dehm, PhD
Bio: I am a 5th year student in the University of Minnesota Medical Scientist Training Program. My research interests focus on metabolism in the context of cancer. My career goal is to become a physician scientist focused on genitourinary malignancies.
Elucidating the Role of Extracellular Lipids in Ferroptosis in Castration Resistant Prostate Cancer
Authors: Valentín López, JC; Ho, Y; Dehm, S
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Joshua Fry, MS | fryxx094@umn.edu
Poster Location: Zone A, Number 10
Mentor: Rendong Yang, PhD
Bio: I am currently a 2nd year PhD student in Bioinformatics and Computational Biology at the University of Minnesota. My research focuses on understanding alternative splicing and its role in cancer.
Detection of high-confidence exitron splicing events reveals up-regulated 3'UTR splicing in cancer
Authors: Fry J, Yang R
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Kayum Alam, PhD | skalam@umn.edu
Poster Location: Zone A, Number 11
Mentor: Luke Hoeppner, PhD
Activation of dopamine D2 receptor signaling in endothelium reduces lung cancer growth
Authors: Alam SK, Wang L, Zhu Z, and Hoeppner LH
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Li Wang, PhD, MD | wang8752@umn.edu
Poster Location: Zone A, Number 12
Mentor: Luke Hoeppner, PhD
Bio: I am a postdoctoral fellow and molecular biology expert with a strong background using animal models or cells to study lung cancer and vascular biology at the University of Minnesota, The Hormel Institute.
Dual inhibition of EGFR and HER3 prevents EGFR TKI-refractory lung cancer progression
Authors: Wang L, Alam SK, Hoeppner LH
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Shambojit Roy, PhD | roys@umn.edu
Poster Location: Zone A, Number 13
Mentor: Paolo Provenzano, PhD
Bio: During my PhD at the University of Colorado, Boulder, I was working on developing novel proteins (affibodies) that could not only specifically target receptors over-expressed on cancer cells but also convert a prodrug to an chemotherapeutic drug 5-FU at the tumor tissue. Due to my experience in cancer targeting and cellular imaging, I was interested in this Postdoc position with Paolo as a mentor, as currently we are studying the migration of engineered T cells into in vitro 3D pancreatic tumor models, using advanced imaging techniques such as multiphoton microscopy and second harmonic generation (SHG).
T cell migration through obstacles presented by the microenvironment of pancreatic tumor spheroids
Authors: Roy S, Chen Z, Qian G, Provenzano P.
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Summer Gerhardt | gerha081@umn.edu
Poster Location: Zone A, Number 14
Mentor: Deepali Sachdev, PhD
Bio: I am senior undergraduate student working towards a B.S. in Genetics, Cell Biology & Development with aspirations to attend medical school.
Acquired resistance to CDK4/6 inhibitors is associated with upregulated IGF1R and IR signaling
Authors: Gerhardt SL, Baar CS, Johnson IR, Sachdev D
Sneha Venkatachalapathy, PhD | venka251@umn.edu
Poster Location: Zone A, Number 1
Mentor: Mark Distefano, PhD
Chemoenzymatic assembly of protein bioconjugates for in vitro and in vivo imaging and drug delivery.
Authors: Sneha Venkatachalapathy, Shelby Auger, Yiao Wang, Ali Salehi Farid, Seyed Heydar Moravej, Jonas V. Schaefer, Andreas Pückthun, Mohammad Rashidian, Mark D. Distefano
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Vijay Kumar Honnaiah, PhD | kumarv@umn.edu
Poster Location: Zone A, Number 2
Mentor: Natalia Tretyakova, PhD
Bio: I have received my PhD degree in Organic and Medicinal Chemistry from the University of Mysore, India in 2010. For the past 9 years, I have been serving as a scientist/staff at the UMN . My research passions include synthesis of small molecules for cancer therapy, developing new synthetic methodologies, and synthesis of modified DNAs. I am currently focusing on synthesis of chemically -modified DNAs for lung cancer study.
Synthesis of DNA strands containing DEB-FAPy-dG adducts of 1,3-Butadiene
Authors: Vijay Kumar H, Holly DH, Shin YP, Simón G, Christine L, Natalia T
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William Kamm, BS | kamm0042@umn.edu
Poster Location: Zone A, Number 3
Mentor: Frank G. Ondrey, MD, PhD
Bio: William Kamm is a second-year medical student at the University of Minnesota. He received his Bachelor of Science from the University of Wisconsin-Madison in 2022, and his previous research experiences have investigated neurodegenerative disease and cellular senescence.
Genomic Variation of HPV Positive and Negative Head and Neck Squamous Cell Carcinoma
Authors: Kamm WE, Mortenson LJ, Ondrey FG
Sai Harshita Posani, PhD | posan005@umn.edu
Poster Location: Zone C, Number 38
Mentor: Carol Lange, PhD
Mineralocorticoid receptor signaling in Triple-Negative Breast Cancer
Authors: Sai Harshita Posani, Julia Austin and Carol Lange
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WIlliam Kanagy, PhD, BA | Kanag018@umn.edu
Poster Location: Zone C, Number 39
Mentor: Tanya Freedman, PhD
Bio: I completed my PhD at the University of New Mexico studying how the interplay of Fc receptor aggregation, ITAM phosphorylation state, and protein-protein interactions shape signaling outcomes. Now as a postdoc working out of the Center for Immunology my research focuses on how Lyn tunes immune receptor signaling towards a pro- or anti-tumor state.
Defining LynA and LynB signaling in the context of distinct immune receptor signaling motifs
Authors: Kanagy WK, Freedman T
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Ethan Wong, BS
Poster Location: Zone C, Number 40
Mentor: Erin B. Dickerson, PhD
Bio: My name is Ethan Wong and I am a current Researcher 2 in the Dickerson lab. I received by bachelor's degree in biochemistry and genetics from the University of Minnesota in May 2023 and plan to start medical school in the Fall of 2024.
MCT1 as a Potential Target in the Progression of Oral Dysplasia to Invasive Squamous Cell Carcinoma
Authors: Wong EJ, Khammanivong, A, Mutreja I, Dickerson EB, Gopalakrishnan R
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Ivan Wu, PhD | wuivan@umn.edu
Poster Location: Zone C, Number 41
Bio: Dr. Ivan Wu is an Assistant Professor in the School of Public Health, Division of Epidemiology and Community Health. His research identifies social determinants of health disparities across the cancer spectrum from prevention to survivorship quality of life. He uses knowledge gained from epidemiological studies to inform the development of community-engaged health promotion interventions with underrepresented racial/ethnic minority communities in partnership with community-based organizations.
Developing Cancer Prevention Capacity through Community Health Workers in the East African Community
Authors: Wu IHC, Ali A, Ahmed R, Bista S
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Madison Shackelford, BS | shack061@umn.edu
Poster Location: Zone C, Number 42
Mentor: Nicholas Zorko, MD PhD
Bio: Madison is a research technician in the Miller Lab working under Nicholas Zorko, focusing on NK cell immunotherapies for prostate cancer. They are interested in viro-oncology, the connections between hormone sensitivities and immune function, and are hoping to apply to graduate programs to explore this. In their free time they love to hike and explore, cook, and draw.
Optimizing Metastatic, Castration-Resistant Prostate Cancer Therapy Using TriKEs and Patient Samples
Authors: Zorko NA, Hwang JH, Antonarakis ES, Miller JS, Felices M, Shackelford M, Bozicevich A, Phung G, Khaw M, Soignier Y, Walker J, Russell A, Ruglowski J
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Margaret Sleeth, BS, BA | sleet010@umn.edu
Poster Location: Zone C, Number 43
Mentor: Keli Hippen, PhD
Inhibition of ACC in expanded thymic T regulatory cells enhances in vivo suppressive function.
Authors: Sleeth M, Smith KD, Walden S, Hani S, Blazar BR, Hippen KL
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Matia Solomon, BA | solom264@umn.edu
Poster Location: Zone C, Number 44
Mentor: Anna Prizment PhD, MS, MPH
Bio: My name is Matia Solomon, and I am an undergraduate student at the University of Minnesota. Here, I am a member of the BA/MD Direct Matriculation Program, which has allowed me to focus on building the skills required for medical school. Throughout my undergraduate experience, I have focused on psychosocial-outcomes research, with an emphasis on quality of life in cancer survivors; I hope to further explore this field as a future physician.
The Role of Race and Gender in the Relationship Between Cancer and Quality of Life and Depression
Authors: Matia SH, Prizment AE, Jewett PI.
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Sean Tracy, PhD, MD | stracy@umn.edu
Poster Location: Zone C, Number 45
Bio: I am a junior faculty member of the division of hematology, oncology, and transplantation (HOT). I work closely with Drs. Michael Farrar and Veronika Bachanova on models of the T-cell response towards acute lymphoblastic leukemia
A CD4+ T-cell subset protects leukemic cells from immune surveillance, enabling relapse
Authors: Sean I. Tracy, Hrishi Venkatesh, Todd Knutson, Yinjie Qiu, and Michael A. Farrar
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Shruthi Chandra, MD | chand713@umn.edu
Poster Location: Zone C, Number 46
Mentor: Britt K Erickson, MD
Bio: Shruthi Chandra is a 4th year resident physician in Obstetrics & Gynecology at the University of Minnesota. Her particular research interests include HPV related diseases. She is planning to join the Women's Health Specialist group as faculty at the University of Minnesota next year.
HPV Vaccination in Solid Organ Transplant Patients
Authors: Chandra S, Cooke KM, Kamath M, McCarty M, Matas A, Mathson K, Farnsworth M, Tessier K, Erickson BK
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Wenxuan Zhu, BA | zhu00886@umn.edu
Poster Location: Zone C, Number 47
Mentor: Darko Bosnakovski, DVM, PhD
Exploring CIC-DUX4 Sarcoma Surfaceome
Authors: Wenxuan Zhu, Lauren Mills PhD, Darko Bosnakovski DVM, PhD
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Zhijun Guo, PhD | guox0035@umn.edu
Poster Location: Zone C, Number 48
Mentor: David Potter, MD PhD
Bio:
Hexyl-(cuban-1-yl-methyl)-biguanide modulates immune microenvironment in the ER+HER2- SSM2UCD model
Authors: Guo Z1, Lei J1, Venkatesh H1, Owen D1, Bass A2, Cannon C3, McCarra J1, Koniar B1, Flory GM1, Norris B1, Schumacher RJ1, JayaramanS4, Hawse J4, Cardiff RD5, Falck JR6, Ambrose EA1, Georg GI1, Schwertfeger KL1, Farrar MA1, Goetz MP4, and Potter DA1.
1University of Minnesota, Minneapolis, MN; 2Macalester College, St Paul, MN; 3Pomona College, Claremont, CA; 4Mayo Clinic, Rochester, MN; 5University of California, Davis, CA; 6University of Texas Southwestern Medical Center, Dallas, TX