Principal Investigator
Principal Investigator
Andrew Khalil
Assistant Professor, PhD
Postdoc 2024- Whitehead Institute and Wyss Institute
Ph.D. 2017- University of Wisconsin-Madison, Bioengineering and Biomedical engineering
B.S. 2011- College of Charleston, Biochemistry and Molecular Biology
Bio:
Graduate Students
Blessing Ampong
Education: B.Sc. Biomedical Engineering, Kwame Nkrumah University of Science and Technology (KNUST), 2021
Hometown: Kumasi, Ghana
Research interests: Kidney immunity, gene and drug delivery, microphysiological systems development, iPSC-resident immune cell differentiation, regenerative medicine
Project topic: Developing immune-competent kidney organoids for disease modeling and drug toxicity test
Other interests: Table tennis, work out at the gym, and watching movies(occasionally)
Contact: ampon020@umn.edu
Keagan Schmid
Education: B.S. Biomolecular Engineering, Milwaukee School of Engineering
Hometown: Fond du Lac, Wisconsin
Research Interests: Biomaterials, drug delivery, and molecular engineering (with focus on solutions at the intersection of synthetic biology and molecular engineering)
Project description: I am exploring optogenetic transmembrane pumps and their integration into liposomal membranes for controlled molecular transport. My work focuses on developing strategies to ensure these pumps orient uniformly, enabling light-activated transport with high efficiency. By leveraging optogenetics, I aim to create a platform for precise, external control of molecular movement, with potential applications in biotechnology, synthetic biology, and drug delivery. My research combines protein engineering, membrane biophysics, and recombinant expression techniques to optimize pump integration and function. Through experimental validation using calcium transport assays, I am working toward a proof-of-concept system that could be expanded for broader biomedical applications. Ultimately, my goal is to establish foundational technologies that enable new tools for controlled molecular transport, paving the way for future innovations in bioengineering.
Other interests: History, Philosophy, Near Eastern Studies, and esotericism, Typography, and Artificial Intelligence
Contact: schm5433@umn.edu
Luke Knutson
Education: BSc. Biochemistry and Chemistry, South Dakota State University
Hometown: Twin-Cities, Minnesota
Research: Lymphatic system and primary cilia in a biochemistry lab (past), microglia and their interactions with glioblastoma (current). Goal is to elucidate novel processes for therapeutic targeting
Project topic: Developing cerebral organoids to study the glioblastoma microenvironment
Other interests: Hiking, camping, mountain biking, playing board and video games with friends
Contact: knut0776@umn.edu
Yijie Wang
Education: B.S. Biomedical Engineering, Southern University of Science and Technology (SUSTech),
Hometown:
Research interests: Synthetic biology, particulary with interactions within synthetic gene circuits
Project topic: Enhancing sensitivity and selectivity of macrophage-based anti-cancer immunotherapy
Other interests: Anime, video games
Contact: wan02176@umn.edu