Embedded Files
Oh JM, Kim Y, Lee HS, Son H, Heo HJ, Baek SE, Kim EK, Lee JY, Lee KE, Kim YH, Kim HJ. (2024) Paired Transcriptional Analysis of Periodontitis and Peri-Implantitis within same host: a Pilot study. J Dent 151: 105366.
Lee KE*, Pasca di Magliano M*. (2024) Unveiling the culprit: IL17 signaling in the pancreatic epithelium drives tumorigenesis. Cancer Immunol Res OF1-OF2. *Co-corresponding authors
Brown BA, Myers PJ, Adair SJ , Pitarresi JR , Sah-Teli SK, Hart WS, Barbeau M, Leong K, Seyler N, Kane W, Lee KE, Stelow E, Simon MC, Koivunen P, Bauer TW, Stanger BZ, Lazzara MJ. (2024) A histone methylation-mapk signaling axis drives durable epithelial-mesenchymal transition in hypoxic pancreas cancer. Cancer Res 84:1764-1780.
Jain C, Parimi SK, Huang W, Hannifin S, Singhal R, Das NK, Lee KE, Shah YM. (2023) Myeloid Hif2α is not essential to maintain systemic iron homeostasis. Exp Hematol 125-126:25-36.
Lee KE. (2023) Hypoxia as a regulator of tumor stroma and metastasis. Am J Physiol Cell Physiol 324:C10-C13.
Mello A*, Ngodup T*, Lee Y, Donahue KL, Li J, Rao A, Carpenter ES, Crawford HC, Pasca di Magliano M, Lee KE. (2022) Hypoxia promotes an inflammatory phenotype of fibroblasts in pancreatic cancer. Oncogenesis 11:56.*Equal contribution
Li F, Huangyang P, Burrows M, Guo K, Riscal R, Godfrey J, Lee KE, Lin N, Lee P, Blair IA, Keith B, Li B, Simon MC. (2020) FBP1 loss disrupts liver metabolism and promotes tumorigenesis through a hepatic stellate cell senescence secretome. Nat Cell Biol 22:728-739.
Lee KE, Spata M, Maduka R, Vonderheide RH, Simon MC. (2018) Hif1α deletion limits tissue regeneration via aberrant B cell accumulation in experimental pancreatitis. Cell Reports 23:3457-3464.
Li F*, Lee KE*, Simon MC. (2018) Detection of Hypoxia and HIF in Paraffin-Embedded Tumor Tissues. Methods Mol Biol1742:277-282. *Equal contribution
Lee KE, Spata M, Bayne LJ, Buza EL, Durham AC, Allman D, Vonderheide RH, Simon MC. (2016) Hif1α deletion reveals pro-neoplastic function of B cells in pancreatic neoplasia. Cancer Discovery 6:256-269.
In the Spotlight. Cancer Discovery 6:230-232, 2016.
Research Highlight. Nature Reviews Cancer 16:67, 2016.
Editors’ Choice. Science Signaling 9:ec77, 2016.
Lee KE, Simon MC. (2015) SnapShot: Hypoxia-Inducible Factors. Cell 163:1288-1288.e1.
Court H, Amoyel M, Hackman M, Lee KE, Xu R, Miller G, Bar-Sagi D, Bach EA, Bergö MO, Philips MR. (2013) Isoprenylcysteine carboxylmethyltransferase deficiency exacerbates KRAS-driven pancreatic neoplasia via Notch suppression. J Clin Invest 123:4681-4694.
Pylayeva-Gupta Y, Lee KE, Bar-Sagi D. (2013) Microdissection and culture of murine pancreatic ductal epithelial cells. Methods Mol Biol 980:267-279.
Lee KE, Simon MC. (2012) From Stem Cells to Cancer Stem Cells: HIF Takes the Stage. Curr Opin Cell Biol 24:232-235.
Pylayeva-Gupta Y, Lee KE, Hajdu CH, Miller G, Bar-Sagi D. (2012) Oncogenic Kras-induced GM-CSF production supports the development of pancreatic neoplasia. Cancer Cell 21:836-847.
Mallen-St.Clair J, Soydaner-Azeloglu R, Lee KE, Taylor LJ, Livanos A, Pylayeva-Gupta Y, Miller G, Margueron R, Reinberg D, Bar-Sagi D. (2012) EZH2 couples pancreatic regeneration to neoplastic progression. Genes Dev 26:439-444.
Lee KE, Bar-Sagi D. (2010) Oncogenic KRas suppresses inflammation-associated senescence of pancreatic ductal cells. Cancer Cell 18:448-458.
Research Highlight In Brief. Nature Reviews Cancer 11:5, 2011.
Agbunag C, Lee KE, Buontempo S, Bar-Sagi D. (2006) Pancreatic duct epithelial cell isolation and cultivation in two-dimensional and three-dimensional culture systems. Methods Enzymol 407:703-710.
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