Publications

Research From The IASO Team and Our Collaborators

2023

SARS-CoV-2 neutralising antibodies after a second BA.5 bivalent booster

Wang Q, Bowen A, Ho J, Zhang RM, Valdez R, Stoneman E, Gordon A, Liu L, Ho DD. (2023). The Lancet, Oct 31:S0140-6736(23)

10.1016/S0140-6736(23)02278-X


Deep immunological imprinting due to the ancestral spike in the current bivalent COVID-19 vaccine.

Wang Q, Guo Y, Tam AR, Valdez R, Gordon A, Liu L, Ho DD. (2023). Cell Rep Med, Oct 24:101258

10.1016/j.xcrm.2023.101258


Antigenicity and receptor affinity of SARS-CoV-2 BA.2.86 spike 

Wang Q, Guo Y, Liu L, Schwanz LT, Li Z, Nair MS, Ho J, Zhang RM, Iketani S, Yu J, Huang Y, Qu Y, Valdez R, Lauring AS, Huang Y, Gordon A, Wang HH, Liu L, Ho DD (2023). Nature, 23

https://doi.org/10.1038/s41586-023-06750-w


Antibody neutralization of emerging SARS-CoV-2 subvariants: EG.5.1 and XBC.1.6 Wang Q, Guo Y, Zhang RM, Ho J, Mohri H, Valdez R, Manthei DM, Gordon A, Liu L, Ho DD (2023). Lancet Infect Diseases, 23(10), e397-e398. https://www.sciencedirect.com/science/article/pii/S1473309923005558?via%3Dihub


SARS-CoV-2 neutralizing antibodies after bivalent versus monovalent booster
Wang Q, Bowen A, Tam AR, Valdez R, Stoneman E, Mellis IA, Gordon A, Liu L, Ho DD. (2023). Lancet Infect Diseases, 23(5), 527-528. https://www.sciencedirect.com/science/article/pii/S1473309923001810?via%3Dihub


Antibody Response to Omicron BA.4-BA.5 Bivalent Booster
Wang, Q., Bowen, A., Valdez, R., Gherasim, C., Gordon, A., Liu, L., & Ho, D. D. (2023). The New England Journal of Medicine, 388(6), 567–569. https://doi.org/10.1056/NEJMc2213907


Alarming antibody evasion properties of rising SARS-CoV-2 BQ and XBB subvariants
Wang, Q., Iketani, S., Li, Z., Liu, L., Guo, Y., Huang, Y., Bowen, A. D., Liu, M., Wang, M., Yu, J., Valdez, R., Lauring, A. S., Sheng, Z., Wang, H. H., Gordon, A., Liu, L., & Ho, D. D. (2023). Cell, 186(2), 279–286.e8. https://doi.org/10.1016/j.cell.2022.12.018

2022

PARIS and SPARTA: Finding the Achilles’ heel of SARS-CoV-2

Simon, V, Kota, V, Bloomquist, RF, Hanley, HB,  Forgacs, D, Pahwa, S, Pallikkuth, S, Miller, LG, Schaenman, J, Yeaman, MR, Manthei, D, Wolf, J, Gaur, AH,  Estepp, JH, Srivastava, K, Carreño, JM, Cuevas, F, PARIS/SPARTA study group, Ellebedy, AH, Gordon, A, Valdez, R, Cobey, S, Reed, EF, Kolhe, R, Thomas, PG, Schultz-Cherry, S, Ross, TM, Krammer, F. (2022). mSphere. https://digitalcommons.wustl.edu/open_access_pubs/12061/ 


Characterization of the emerging SARS-CoV-2 B.1.621 (Mu) variant

Halfmann, PJ,  Kuroda, M,  Armbrust, T, Theiler, J, Balaram, A, Moreno, GK, Accola, MA, Valdez, R, Kowalski-Dobson, T, Braun, K, Yamayoshi, S, Somsen, E, Baczenas, JJ, McLaughlin, M, Rehrauer, W, Imai, M, Friedrich, TC, O’Connor, SL, O’Conner, D, Gordon, A, Korber, B, and Kawaoka, Y.  (2022). ScienceTranslational Medicine. https://www.science.org/doi/10.1126/scitranslmed.abm4908 


Defining the risk of SARS-CoV-2 variants on immune protection
DeGrace, M.M., Ghedin, E., Frieman, M.B. et al. (2022). Nature. https://doi.org/10.1038/s41586-022-04690-5 


Characterization of a new SARS-CoV-2 variant that emerged in Brazil
Imai M, Halfmann PJ, Yamayoshi S, Iwatsuki-Horimoto K, Chiba S, Watanabe T, Nakajima N, Ito M, Kuroda M, Kiso M, Maemura T, Takahashi K, Loeber S, Hatta M, Koga M, Nagai H, Yamamoto S, Saito M, Adachi E, Akasaka O, Nakamura M, Nakachi I, Ogura T, Baba R, Fujita K, Ochi J, Mitamura K, Kato H, Nakajima H, Yagi K, Hattori SI, Maeda K, Suzuki T, Miyazato Y, Valdez R, Gherasim C, Furusawa Y, Okuda M, Ujie M, Lopes TJS, Yasuhara A, Ueki H, Sakai-Tagawa Y, Eisfeld AJ, Baczenas JJ, Baker DA, O'Connor SL, O'Connor DH, Fukushi S, Fujimoto T, Kuroda Y, Gordon A, Maeda K, Ohmagari N, Sugaya N, Yotsuyanagi H, Mitsuya H, Suzuki T, Kawaoka Y. (2022) Proceedings of the National Academy of Sciences (PNAS) USA. https://www.pnas.org/doi/10.1073/pnas.2106535118 


Long-Term, Infection-Acquired Immunity Against the SARS-CoV-2 Delta Variant in a Hamster Model
Halfmann, P, Kuroda, M, Armbrust, T, Accola, M, Valdez, R, Kowalski-Dobson, T, Rehrauer, W, Gordon, A, Kawaoka, Y. (2022). Cell Reports. https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8801307/