The goal of this study is to determine the efficacy of study drug, Azeliragon as a treatment for severe COVID-19 infections.
Azeliragon is an orally administered inhibitor of the receptor of advanced glycation end products (RAGE) which has been strongly implicated in life threatening COVID-19 infections. Azeliragon is thought to work by blocking this interaction; hence rational is it can work as an effective treatment for COVID-19 infections.