News & Publications

Medical Alert: COVID-19 cases on the rise

An interview with Professor Don Milton (Sept. 10, 2023)

Why Is There Confusion About Whether Masks Prevent COVID-19? Public Perceptions, Misperceptions and the Messaging of Science

May 9, 2023

Statement of Scientists in Response to CDC’s May 7th Announcement Recognizing Inhalation Exposure


We are pleased that in its updated Scientific Brief: SARS-CoV-2 Transmission  CDC acknowledged today that transmission of the SARS-CoV-2 virus through inhalation of tiny aerosol particles is a primary route of exposure and that risk of inhaling the virus is greatest close to an infected person. This is an important and major step forward.


[Note (May 11): the CDC has recently made improvements to the How COVID-19 Spreads website.]

However, we are concerned that CDC’s accompanying document How COVID-19 Spreads is misleading, and potentially harmful. ... [expand to read more]

In that document CDC says that breathing in small droplets and particles (i.e., aerosols) that contain the virus when people are far apart or have been in the same enclosed space for more than a few minutes is UNCOMMON (our emphasis). This will lead people to continue to think that maintaining distance is sufficient to prevent transmission.

 

We know that transmission at distances beyond 6 feet occurs because of superspreader events, careful studies of smaller outbreaks, and the physics of aerosols. It can easily happen indoors in a poorly ventilated environment, when people are not wearing masks.

 

There is clear consensus among aerosol scientists and epidemiologists that inhalation of small aerosol particles, including at distances of greater than six feet, is a major driver of the COVID-19 pandemic. To slow transmission and save lives, it is crucial that CDC update its guidance and recommendations to address and highlight the importance of improved ventilation and using NIOSH approved respirators, especially in indoor locations where the virus may accumulate in the air. 

 

Moreover, OSHA must issue an Emergency Temporary Standard to control workplace exposures, including inhalation exposure, as soon as possible in order to protect workers and reopen the economy safely.

 

As CDC has made clear, vaccination alone will not stop this pandemic. Mitigation measures are also needed to limit exposures. We must control inhalation exposure of small aerosol particles to end this pandemic. 

 

CDC must immediately update and strengthen its guidelines and recommendations to protect the public and workers for inhalation exposures to SARS-CoV-2. 

 

More on the importance of addressing aerosol transmission and the steps needed to control exposures can be found in the letter several of us sent to federal COVID-19 leaders in February 2021.


David Michaels, PhD, MPH

Professor, Department of Environmental and Occupational Health

Milken Institute School of Public Health

The George Washington University

Former Assistant Secretary if Labor for OSHA (2009-2017)

drdavidmchaels@gmail.com 


Donald K. Milton, MD, DrPH

Professor, Institute for Applied Environmental Health

Department of Epidemiology and Biostatistics

University of Maryland School of Public Health

dmilton@umd.edu

301-405-0389


Linsey C. Marr, PhD

Professor, Civil and Environmental Engineering

Center for Emerging, Zoonotic, and Arthropod-Borne Pathogens

Virginia Tech

lmarr@vt.edu and mediarelations-g@vt.edu


Lisa M Brosseau, ScD, CIH

Professor (retired)

Research Consultant, University of Minnesota, Center for Infectious Disease Research and Policy

brosseau@umn.edu


Peg Seminario

Safety and Health Director, AFL-CIO (retired)

pseminario228@gmail.com


Kimberly A. Prather, Ph.D.

Director, NSF Center for Aerosol Impacts on Chemistry of the

Environment

Distinguished Professor

Distinguished Chair in Atmospheric Chemistry

Scripps Institution of Oceanography

University of California, San Diego

kprather@ucsd.edu 


Michael T. Osterholm, PhD, MPH

Regents Professor, McKnight Presidential Endowed Chair in Public Health

Director, Center for Infectious Disease Research and Policy

University of Minnesota

mto@umn.edu



What to do about K-12 Schools? 

Background: The CDC was slow to accept that inhalation of viral aerosols is how many people get infected... [expand to read more]

for both reasons of backwardness of the medical-hospital infection control profession and political influences of the AHA and corporate medicine. Their guidance’s list of the five key prevention strategies for K-12 schools, even with the 19 March 2021 update is still not consistent with the scientific evidence. It does not list ventilation, an effective engineering control, as the first key strategy. The general public knows airborne transmission is a reality and the importance of inhalation exposure to infectious aerosols has been extensively covered by CBS, MSNBC, NPR, the Washington Post, the New York Times, the Atlantic and many other mainstream media to the point that a Post journalist told me on March 19th that the topic wasn’t even considered newsworthy anymore. This lack of science-based guidance from CDC, focusing on surface cleaning and not air cleaning, severely complicates the situation for decision makers.

As of March 20, 2021, we are still at high, and most recently, increasing levels of transmission in Maryland and the US generally, even though we are down from the tragic peak levels of early January. This is not a time to relax our vigilance. But we do know enough today, that if we employ the science, we can make schools and workplaces safer and mitigate the serious impacts of school and workplace closures by opening up with stringent controls – and by that I mean not just mask mandates.

The science of worker and building occupant protection from hazardous aerosols and the hierarchy of effective controls is well established. Following the hierarchy of control, it is key to put engineering strategies in place before much less-effective controls that rely on human behavior. The CDC’s recommendations, viewed in light of this hierarch is completely upside down, putting individual behaviors first (masks, distancing, and handwashing) and cleaning and administrative controls (contract tracing) last. Furthermore, the CDC completely fails to specifically recommend the single most effective intervention, ventilation. Instead, they bury mention of ventilation behind sanitizing doorknobs, even though their own scientific briefs acknowledge that touching contaminated objects doesn’t seem to be an important mode of transmission.

Here are Dr. Milton's recommendation for five key prevention strategies for K-12 schools:

Extensive surface decontamination is not a key control. Upgrading normal cleaning practices and use of EPA listed cleaning agents effective against coronaviruses should be encouraged especially where this has been reduced by fiscal constraints on school budgets. These recommendations are in line with the well-established hierarchy of controls and the scientific evidence about how COVID-19 spreads. Ionization technologies are not proven solutions -- ventilation, filtration, and ultraviolet air sanitation are. 

Better fitting masks

To be better protected against inhaling virus floating in the air ... [expand to read more about  how and  why]

To be better protected against inhaling virus floating in the air (and to release less too if you are infected), better fitting masks are important. William Lindsley, a research bioengineer at NIOSH, presented his research at a UMD SPH MIAEH seminar on March 23 showing that there are several ways to make a mask better. Many surgical / medical procedure masks have good filters (not all unfortunately, some good brands are Ambrust and Zubrex, there are others), but they leak a lot around the edges (foggy glasses anyone?). So, get them to fit tighter and leak less you can use a mask brace, a tight fitting cloth mask over the medical mask, or tuck the mask. The brace is best, a cloth mask is good (depends on the mask), and tucking works pretty well too. Tucking seems tricky, but if you watch this video from UNC, it helps get the hang of it. 

Recent news coverage of StopCOVID@UMD team members

D.C.-area health officials urge precautions as coronavirus cases rise The Washington Post, July 30, 2022

2 COVID experts say they are wearing masks outside when it's crowded as the highly infectious Omicron BA.5 variant spreads Insider, July 13, 2022

Monkeypox Can Be Airborne, Too The Ney York Times, June 7, 2022

The Covid Roulette: The Hard Truth About The WHCA Dinner The Pavlovic Today, May 11, 2022

We Have the Technology to Stop Superspreading Without Masks The New York Times, April 21, 2022 

Coronavirus FAQ: I'm a one-way masker. With mask mandates going away, is that helpful? NPR. April 19, 2022.

What do we know about “stealth omicron” so far? Associated Press. ABC News. PBS. April 12, 2022.

Saliva Testing for COVID-19 Quicker, Safer Than Nasal Swabs ASM, March 21, 2022

Saliva testing for COVID-19 accurate, provides earlier diagnosis, study finds UPI, March 21, 2022

Is omicron leading us closer to herd immunity against COVID-19? Associated Press, February 23, 2022

Which masks are safest? Schools around the country struggle to answer. The Washington Post. Jan 28, 2022.

Want to keep omicron away? Wear a better mask, like the N95. Tampa Bay Times, January 25, 2022

How do I know if I have a cold, the flu or COVID-19? Associated Press, ABC News, The Seattle Times January 7, 2022

Omicron is spreading at lightning speed. Scientists are trying to figure out why, December 31, 2021

Is the Coronavirus Getting Better at Airborne Transmission? The New York Times, October 1, 2021

New studies hint that the coronavirus may be evolving to become more airborne, ScienceNews, August 17, 2021 

To Mask or Not to Mask? University of Maryland School of Public Health, July 12, 2021

The virus is an airborne threat, the C.D.C. acknowledges. New York Times, May 7, 2021.

Ask KHN-PolitiFact: I’ve Recovered From Covid. Why Do I Still Have to Mask Up? Kaiser Health News, April 16, 2021

How one restaurant’s experiment may help diners breathe safely, Washington Post, April 14, 2021

Has the Era of Overzealous Cleaning Finally Come to an End? New York Times, April 8, 2021

As vaccinations increase, you may want to dine indoors again. Here’s what to consider. Washington Post, March 19, 2021

Three Feet or Six? Distancing Guideline for Schools Stirs Debate, New York Times, March 16, 2021

Will schools fully reopen? It may depend on whether students have to sit six feet apart. Washington Post, March 11, 2021

Pandemic Advances Scientific Understanding Of Viruses' Air Transmission, All Things Considered, NPR, December 28, 2020

For Scientists Who Study Virus Transmission, 2020 Was A Watershed Year. NPR article by Nel Greenfieldboyce, December 26, 2020

Indoor Dining and the Spread of Coronavirus. Dr. Milton was on the Brian Lehrer Show WNYC, December 15, 2020

UMD Scientists Say Vice Presidential Debate Needs Air Filtration System Due To Coronavirus. CBS Baltimore, October 7, 2020.

Beyond Plexiglass: Scientists Say This Simple Solution Could Keep VP Debate Safer. NPR, October 7, 2020.

The plexiglass barriers at tonight’s debate will be pretty useless, virus experts say. New York Times, October 7, 2020.

Answering COVID's Big Questions on Campus. Maryland Today, October 6, 2020.

The Flu May Linger in the Air, Just Like the Coronavirus, The New York Times, July 14, 2020. 

We Need to Talk About Ventilation. Tufekci Z. The Atlantic. July 30, 2020.

Recent publications from StopCOVID@UMD Team

Lai, J., German, J., Hong, F., Tai, S.-H. S., McPhaul, K. M., & Milton, D. K. (2022). Comparison of saliva and midturbinate swabs for detection of SARS-COV-2. Microbiology Spectrum, 10(2). https://doi.org/10.1128/spectrum.00128-22 

Oluwasanmi O Adenaiye, Jianyu Lai, P Jacob Bueno de Mesquita, Filbert Hong, Somayeh Youssefi, Jennifer German, S-H Sheldon Tai, Barbara Albert, Maria Schanz, Stuart Weston, Jun Hang, Christian Fung, Hye Kyung Chung, Kristen K Coleman, Nicolae Sapoval, Todd Treangen, Irina Maljkovic Berry, Kristin Mullins, Matthew Frieman, Tianzhou Ma, Donald K Milton, University of Maryland StopCOVID Research Group, Infectious Severe Acute Respiratory Syndrome Coronavirus 2 (SARS-CoV-2) in Exhaled Aerosols and Efficacy of Masks During Early Mild Infection, Clinical Infectious Diseases, 2021;, ciab797, DOI: 10.1093/cid/ciab797

Morawska, L., Allen, J., Bahnfleth, W., Bluyssen, P.M., Boerstra, A., Buonanno, G., ... Yao, M. (2021, May 14). A paradigm shift to combat indoor respiratory infection. Science. 10.1126/science.abg2025

Adenaiye, O., Bueno de Mesquita, P. J., Wu, Q., Hong, F., Lai, J., Chen, S., & Milton, D. K. (2021). The effect of Covid‐19 Stay‐at‐home order and campus closure on the prevalence of acute respiratory infection symptoms in college campus cohorts. Influenza and Other Respiratory Viruses, 15(3), 331–335. https://doi.org/10.1111/irv.12837 

Prather K, Marr L, Schooley R, McDiarmid M, Wilson M, Milton DK. Airborne Transmission of SARS-CoV-2, Science 05 Oct 2020. DOI: 10.1126/science.abf0521

Milton DK. A Rosetta Stone for Understanding Infectious Drops and Aerosols. J Pediatric Infect Dis Soc 2020;Available from: https://academic.oup.com/jpids/article/doi/10.1093/jpids/piaa079/5875939 (accepted manuscript here if you cannot access journal webpage)

Morawska L, Milton DK. It is Time to Address Airborne Transmission of COVID-19. Clin Infect Dis 2020;Available from: https://academic.oup.com/cid/article/doi/10.1093/cid/ciaa939/5867798

Bueno de Mesquita PJ, Noakes CJ, Milton DK. Quantitative aerobiologic analysis of an influenza human challenge-transmission trial. Indoor Air 2020;Available from: https://onlinelibrary.wiley.com/doi/abs/10.1111/ina.12701

Bueno de Mesquita PJ, Nguyen-Van-Tam J, Killingley B, et al. Influenza A (H3) illness and viral aerosol shedding from symptomatic naturally infected and experimentally infected cases. Influenza Other Respir Viruses 2020;irv.12790. https://onlinelibrary.wiley.com/doi/abs/10.1111/irv.12790

Chia PY, Coleman KK, Tan YK, et al. Detection of air and surface contamination by SARS-CoV-2 in hospital rooms of infected patients. Nature Communications 2020;11(1):2800. https://www.nature.com/articles/s41467-020-16670-2

Morawska L, Tang JW, Bahnfleth W, et al. How can airborne transmission of COVID-19 indoors be minimised? Environ Int 2020;142:105832. https://www.sciencedirect.com/science/article/pii/S0160412020317876?via%3Dihub

Nguyen-Van-Tam JS, Killingley B, Enstone J, et al. Minimal transmission in an influenza A (H3N2) human challenge-transmission model within a controlled exposure environment. PLoS Pathog 2020;16(7):e1008704. https://journals.plos.org/plospathogens/article?id=10.1371/journal.ppat.1008704

Leung NHL, Chu DKW, Shiu EYC, et al. Respiratory virus shedding in exhaled breath and efficacy of face masks. Nature Medicine 2020;1–5. https://www.nature.com/articles/s41591-020-0843-2

Zhu S, Jenkins S, Addo K, et al. Ventilation and laboratory confirmed acute respiratory infection (ARI) rates in college residence halls in College Park, Maryland. Environment International 2020;137:105537. http://www.sciencedirect.com/science/article/pii/S0160412019341108

Fennelly KP, Acuna-Villaorduna C, Jones-Lopez E, Lindsley WG, Milton D. Microbial Aerosols: New Diagnostic Specimens for Pulmonary Infections. CHEST [Internet] 2019 [cited 2019 Nov 20];0(0). Available from: https://journal.chestnet.org/article/S0012-3692(19)34113-3/abstract 

Yan J, Grantham M, Pantelic J, et al. Infectious virus in exhaled breath of symptomatic seasonal influenza cases from a college community. Proc Natl Acad Sci USA 2018;115(5):1081–6. https://www.pnas.org/content/115/5/1081