Topics in Depth

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Aptamers are selected through a process called SELEX. After the aptamers are selected, the next step is for the selection pools to be sent for sequencing to identify potential aptamer candidates.

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Sanger and Illumina: two methods of sequencing, differing in use and function. Sanger Sequencing is a traditional method of sequencing, whereas Illumina is a high-throughput, next-generation method of sequencing.

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There are many different methods to analyze aptamer sequencing data. From clustering to motif finding to secondary structures; the information determined from analysis can then provide us with the best possible aptamer candidates.

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This page introduces several tools, which are can be used for aptamer sequencing data analysis.