"On the cover: Gram-negative bacteria are enclosed by an asymmetric lipid bilayer that protects from environmental stresses, including antibiotics. In this issue, Palmer et al. report that the maintenance of lipid asymmetry contributes to outer membrane barrier function, antibiotic resistance, and virulence in the bacterium Acinetobacter baumannii. The image represents the finding that a suppressor mutant isolated from lungs of mice contained a native insertion hop that restored outer membrane barrier function, antibiotic resistance, and virulence. Digital image by Alexa Marcus."

Modulating Isoprenoid Biosynthesis Increases Lipooligosaccharides and Restores Acinetobacter baumannii Resistance to Host and Antibiotic Stress

Palmer LD, Minor KE, Mettlach JA, Rivera ES, Boyd KL, Caprioli RM, Spraggins JM, Dalebroux ZD, Skaar EP. Cell Rep. 2020 Sep 8;32(10):108129. doi: 10.1016/j.celrep.2020.108129. PMID: 32905776; PMCID: PMC7519801.

https://www.cell.com/cell-reports/fulltext/S2211-1247(20)31118-9

Palmer LD, Jordan AT, Maloney KN, Farrow MA, Gutierrez DB, Gant-Branum R, Burns WJ, Romer CE, Tsui T, Allen JL, Beavers WN, Nei YW, Sherrod SD, Lacy DB, Norris JL, McLean JA, Caprioli RM, Skaar EP. Metallomics. 2019 May 22;11(5):982-993. doi: 10.1039/c8mt00360b. PMID: 30968088; PMCID: PMC6531343.

https://pubs.rsc.org/en/content/articlelanding/2019/MT/C8MT00360B#!divAbstract