Microbes form diverse communities throughout the human body
Metabolites produced by microbes mediate host metabolic and immune health
It would be useful to know what the default gut microbiome looks like so that we can differentiate between a healthy and unhealthy gut microbiome
Studies have shown that a specific few bacteria populations fluctuate throughout the year, but we want to see if the overall fluctuations of the thousands of bacteria in the gut microbe are enough of a signal to predict the time of year just from the different population levels
The dynamic nature of host microbial communities is complex and has not yet been characterized using a machine learning model.
If we can develop a model that can predict the time of year that a microbiome sample was collected based on compositional signatures alone, it would demonstrate the existence of seasonal microbial variation on a global population level.