We have developed a new method for selectively cleaving intact proteins in the gas phase. The first paper on this subject was recently published in JACS.
We know that Tau and Amyloid Beta are both involved in Alzheimer's Disease, yet there has never been a simple explanation connecting them. Here, we show that Amyloid beta interferes with tau binding to microtubules, providing the missing nexus of interaction.
Want hard-core mass spec? We've got that too. Here we examine the likelihood that we're all going to die from abundant hydroxyl radicals in water microdroplets (spoiler- we're going to be okay).