Publications

Google scholar profile

Full publication list (Pubmed)

(trainee names are underlined)

1. Goodkey K., Wischmeijer A., Perrin L., Watson AES., Qureshi L., Cordelli M.D., Toni F., Gnazzo M., Benedicenti F., Elmaleh-Bergès M., Low K.J. and Voronova A. (2024) Olfactory bulb anomalies in KBG syndrome mouse model and patients. BMC Medicine 22:158 https://doi.org/10.1186/s12916-024-03363-6 

2. de Almeida M.M.A.*, Watson A.E.S.*, Bibi S., Dittmann N.L., Goodkey K., Sharafodinzadeh P., Galleguillos D., Nakhaei-Nejad M., Kosaraju J., Steinberg N., Wang B.S., Footz T., Giuliani F., Wang J., Sipione S., Edgar J.M., Voronova A#. (2023) Fractalkine enhances oligodendrocyte regeneration and remyelination in a demyelination mouse model. Stem Cell Rep., 18:1-15 https://doi.org/10.1016/j.stemcr.2022.12.001

*co-first authors

This paper was featured in National Post (Healthing Section), CBC Edmonton, Estonian Life, Neuroscience News, Multiple Sclerosis News Today, RegMedNet and University of Alberta Folio magazine as well as by MS Canada 

3. Dittmann N.L., Torabi, P., Watson A., Scott Y. and Voronova A. (2023) Culture protocol and transcriptomic analysis of murine SVZ NPCs and OPCs. Stem Cell Reviews and Reports 19: 983-1000 https://doi.org/10.1007/s12015-022-10492-z

4. de Almeida M.M.A., Goodkey K. and Voronova A. (2023) Regulation of microglia function by neural stem cells. Front. Cell. Neurosci. 17:1130205  https://doi.org/10.3389/fncel.2023.1130205

5. Kierzkowska O., Sarino K., Carter D., Marchi E., Voronova A., Lyon G. (2023) Documentation and prevalence of prenatal and neonatal outcomes in a cohort of individuals with KBG syndrome Am. J. Med. Genet. A, In press https://doi.org/10.1002/ajmg.a.63311 

6. Li Y*., Dittmann N.L*., Watson A.E.S., de Almeida M.M.A., Footz T., Voronova A. (2022). Hepatoma derived growth factor enhances oligodendrocyte genesis from subventricular zone precursor cells ASN Neuro 14:1-20, https://doi.org/10.1177/17590914221086340

*co-first authors

This paper was featured in University of Alberta Folio magazine and by Women and Children’s Health Research Institute (WCHRI) 

7. Guo L., Park J., Yi E., Marchi E., Kibalnyk Y., Voronova A., Hsieh T-C., Krawitz PM, Lyon GJ. (2022) KBG Syndrome: Prospective Videoconferencing and Use of AI-driven Facial Phenotyping in 25 New Patients. (2022) Eur J Hum Genet., 30(11):1244-1254 https://doi.org/10.1038/s41431-022-01171-1

8. Shaha S., Patel K., Saadat S., Panahi S., de Almeida M.M.A., Voronova A., Riddell M. (2022). Human placenta and trophoblasts simultaneously express three isoforms of atypical protein kinase-c Placenta 119:39-43 https://doi.org/10.1016/j.placenta.2022.01.015

9. Watson A.E.S., Almeida M.M.A., Dittmann N., Li Y., Torabi P., Footz T., Vetere G., Galleguillos D., Sipione S., Cardona A.E. and Voronova A. (2021). Fractalkine signalling regulates oligodendroglial cell genesis from SVZ precursor cells. Stem Cell Rep., 16(8):1968–1984 https://doi.org/10.1016/j.stemcr.2021.06.010

This paper was featured in Multiple Sclerosis News Today magazine, University of Alberta Folio magazine, International News Outlet (in Spanish) as well as by MS Canada and Women and Children’s Health Research Institute (WCHRI) 

10. de Almeida, M.M.A.; Pieropan, F; Footz, T. David, J.M.; David, J.P.; Silva, V.D.A.; Souza. C.S.; Voronova, A.; Costa, S.L.; Butt, A.M. (2021). Agathisflavone modifies microglia activation state and increases the extent of developmental myelination in ex vivo cerebellar slices culture. J. Neuroimmune Pharmacol. https://doi.org/10.1007/s11481-021-09991-6

11. Roth D.M., Baddam P., Lin H., Garcia M.V., Aponte J.D., De Souza ST., Godziuk D., Watson A.E.S., Footz T., Schachter N.F., Egan S.E., Hallgrimsson B., Graf D.* , Voronova A.*  (2021). The chromatin regulator Ankrd11 controls palate and cranial bone development Front. Cell Dev. Biol. 9: 645386. https://doi.org/10.3389/fcell.2021.645386

* co-corresponding authors

Role in publication: Funding acquisition, provision of resources, project conceptualization and development, experimental design, manuscript writing, formal supervision of trainees (co-authors) and mentorship of first author.

12. Bhattacherjee A., Daskhan G.C., Bains A., Watson A.E.S., Eskandari-Sedighi G., St Laurent C.D., Voronova A., Macauley M.S. (2021). Increasing phagocytosis of microglia through targeting CD33 with liposomes displaying glycan ligands J Control Release, 10(338):680-693. https://doi.org/10.1016/j.jconrel.2021.09.010

13. Watson A., Goodkey K., Footz T. and Voronova A.# (2020). Regulation of CNS precursor function by neuronal chemokines Neurosci Lett. 715:134533, issue on “The Oligodendrocyte Niche in Development and Repair” https://doi.org/10.1016/j.neulet.2019.134533

14.  Zahr S.K., Yang G., Kazan H., Borrett M.J., Yuzwa S.A., Voronova A., Kaplan D.R. and Miller F.D. (2018). A translational repression complex in developing mammalian neural stem cells that regulates neuronal specification Neuron 97(3):520–537.e6. https://doi.org/10.1016/j.neuron.2017.12.045

15. Voronova A., Yuzwa S.A., Wang B., Siraj Z., Syal. C., Wang J., Kaplan D. R. and Miller F. D. (2017). Migrating interneurons secrete fractalkine to promote oligodendrocyte formation in the developing mammalian brain Neuron 94(3):500-516.e9. Featured article. https://doi.org/10.1016/j.neuron.2017.04.018

This paper was featured in Bandopadhayay P. and Stiles C.D. “Population Control: Cortical Interneurons Modulate Oligodendrogenesis” Neuron (2017) 94(3):415-417 and by the Canadian Association for Neuroscience (CAN).

16. Yuzwa S.A, Borrett M.J., Innes B., Voronova A., Ketela T., Kaplan D.R., Bader, G.D. and Miller F.D. (2017). Developmental emergence of adult neural stem cells as revealed by single cell transcriptional profiling Cell Rep. 21(13):3970-3986. https://doi.org/10.1016/j.celrep.2017.12.017

17. Yang G., Cancino G. I., Zahr S., Guskjolen A., Voronova A., Gallagher D., Frankland P.W., Kaplan D. R. and Miller F. D. (2016). A Glo1-methylglyoxal pathway that is perturbed in maternal diabetes regulates embryonic and adult neural stem cell pools in offspring Cell Rep. 17(4):1022-1036. https://doi.org/10.1016/j.celrep.2016.09.067

18. Fair J. V.*, Voronova A.*, Bosiljcic N., Rajgara R., Blais, A. and Skerjanc I. S. (2016). BRG1 interacts with GLI2 and binds Mef2c gene in a Hedgehog signalling dependent manner during in vitro cardiomyogenesis. BMC Dev Biol 16(1):27. https://doi.org/10.1186/s12861-016-0127-8

*co-first authors

Role in publication: Manuscript writing, experimental design, data analysis and experimental work (purification of Gli2 and identification of Brg1 as interacting partner by mass-spectrometry, initial characterization of mouse ES cells expressing Gli2, 80% of revisions). I directly supervised J. Fair’s experiments together with Dr. Blais while Dr. Skerjanc was on extensive medical leave.

19. Gallagher D.*, Voronova A.*, Zander, M. A., Cancino G. I., Bramall A., Krause M. P., Abad C., Tekin M., Neilsen P. M., Callen D. F., Scherer S. W., Keller G. M., Kaplan D.R., Walz K. and Miller F. D. (2015). Ankrd11 is a chromatin regulator involved in autism that is essential for neural development. Dev. Cell, 32(1): 31-42. https://doi.org/10.1016/j.devcel.2014.11.031

*co-first authors.

Role in publication: Manuscript writing, experimental design, data analysis and experimental work describing Ankrd11 molecular mechanism (neurosphere culture, microarrays, western blots, chromatin immunoprecipitation, quantitative PCR).

20. Tsui D., Voronova A., Gallagher D., Kaplan D. R., Miller F. D. and Wang J. (2014). CBP regulates the differentiation of interneurons from ventral forebrain neural precursors during murine development. Dev. Biol. 385:230-241. https://doi.org/10.1016/j.ydbio.2013.11.005

21. Al Madhoun A., Voronova A., Ryan T., Zakariyah A., McIntire C., Gibson L., Shelton M., Ruel M. and Skerjanc I.S. (2013). Testosterone enhances cardiomyogenesis in stem cells and recruits AR to MEF2C and HCN4 genes. J. Mol. Cell. Card. 60:164-171. https://doi.org/10.1016/j.yjmcc.2013.04.003

22. Wong J., Mehta V., Voronova A., Coutu J., Ryan T., Shelton M., and Ilona S. Skerjanc (2013). ß-catenin is essential for efficient in vitro skeletal muscle progenitor form ation but can be partially compensated by retinoic acid signalling. PLoS ONE 8(2): e57501. https://doi.org/10.1371/journal.pone.0057501

23. Voronova A., Coyne E., Al Madhoun A., Fair J., Bosiljcic N., St-Louis C., Li G., Thurig S., Wiper-Bergeron N., Wallace V.A. and Skerjanc I.S. (2013). Hedgehog signalling regulates MyoD expression and activity. JBC 288(6):4389-4404 https://doi.org/10.1074/jbc.M112.400184

24. Wan S., Goto K., Staebler J. M., Mottiar Y., Johnson A. M., Voronova A., Blais D. R., Zaidi M. A., and Altosaar I. (2012). Bacterial nitrous oxide reductase expressed in transgenic plants: evidence for sufficient anaerobicity to permit activity. Can. J. Plant Sci., 92(7): 1283-1294 https://doi.org/10.4141/cjps2011-284

25. Voronova A., Al Madhoun A., Fischer A., Shelton M., Karamboulas C., and Skerjanc I.S. (2012). Gli2 and MEF2C activate each other’s expression and function synergistically during cardiomyogenesis in vitro Nucleic Acids Res. 40: 3329-3347. Featured article (Featured Articles represent the top 5% of NAR papers in terms of originality, significance and scientific excellence) https://doi.org/10.1093/nar/gkr1232

26. Voronova A., Fischer A., Ryan T., Al Madhoun A., and Skerjanc I.S. (2011). Ascl1/Mash1 is a novel target of Gli2 during Gli2-induced neurogenesis in P19 EC cells. PLoS ONE 6, e19174 https://doi.org/10.1371/journal.pone.0019174

27. Avdic V., Zhang P., Lanouette S., Voronova A., Skerjanc I., and Couture J. F. (2011). Fine-tuning the stimulation of MLL1 methyltransferase activity by a histone H3 based peptide mimetic. FASEB J 25, 960-967. https://doi.org/10.1096/fj.10-171959

28. Gianakopoulos P. J., Mehta V., Voronova A., Cao Y., Yao Z., Coutu J., Wang X., Waddington M. L., Tapscott S. J. and Skerjanc I.S. (2011). MyoD directly upregulates premyogenic mesoderm factors during induction of skeletal myogenesis in stem cells. JBC 286, 2517-2525. https://doi.org/10.1074/jbc.M110.163709

29. Savage J., Voronova A., Mehta V., Sendi-Mukasa F. and Skerjanc S. I. (2010). Canonical Wnt signalling regulates Foxc1/2 expression in P19 cells. Differentiation 79, 31-40. https://doi.org/10.1016/j.diff.2009.08.008

30. Voronova A., Meyer-Klaucke W., Meyer T., Rompel A., Sillard R., and Palumaa P. (2007). Oxidative switches on functioning of mammalian copper chaperone Cox17. Biochem. J. 408, 39-48. https://doi.org/10.1042/BJ20070804

31. Voronova A., Kazantseva J., Tuuling M., Sokolova N., Sillard R., Palumaa P. (2007). Cox17, a copper chaperone for cytochrome c oxidase: Expression, purification, and formation of mixed disulphide adducts with thiol reagents. Protein Expr Purif. 53, 138-144. https://doi.org/10.1016/j.pep.2006.11.014

32. Palumaa P., Kangur L., Voronova A., Sillard R. (2004). Metal-binding mechanism of Cox17, a copper chaperone for cytochrome c oxidase. Biochem J. 382, 307-314. https://doi.org/10.1042/BJ20040360