Renee C. Geck, Naomi G. Moresi, Leah M. Anderson, yEvo Students, Rebecca Brewer, Timothy R. Renz, M. Bryce Taylor, Maitreya J. Dunham

Summary: 

Yeast can adapt to grow in high concentrations of caffeine. In collaboration with high school students, we grew yeast in increasing concentrations of caffeine to select for ones better adapted to caffeine. We sequenced these yeast to identify mutations that promote growth in caffeine, and showed they are related to pumping caffeine out of the cell, or changing pathways within the cell that are otherwise blocked by caffeine.

Complete Paper is available on the on the G3 - Genes, Genomes, Genetics website and is titled “Experimental evolution of S. cerevisiae for caffeine tolerance alters multidrug resistance and TOR signaling pathways” 

Renee C. Geck, Naomi G. Moresi, Leah M. Anderson, yEvo Students, Rebecca Brewer, Timothy R. Renz, M. Bryce Taylor, Maitreya J. Dunham

Summary: 

Yeast can adapt to grow in high concentrations of caffeine. In collaboration with high school students, we grew yeast in increasing concentrations of caffeine to select for ones better adapted to caffeine. We sequenced these yeast to identify mutations that promote growth in caffeine, and showed they are related to pumping caffeine out of the cell, or changing pathways within the cell that are otherwise blocked by caffeine.

Complete Paper is available on the on the bioRxiv preprint server for Biology and is titled “Experimental evolution of S. cerevisiae for caffeine tolerance alters multidrug resistance and TOR signaling pathways” 

Experimental evolution of caffeine-tolerant yeast alters multidrug resistance and PP2A-like signaling pathways

Renee C. Geck, Naomi G. Moresi, Rebecca Brewer, Tim Renz, yEvo Students, M. Bryce Taylor, and Maitreya J. Dunham

Research done in Intro to Biotech class through a coordination with the yEvo program and UW Genome Sciences.

Transcription Motifs in Quiescent Yeast Cells

Mahelat Alamerew, Cucinotta Christine Ph.D, Gennifer Goode Ph. D, Basic Sciences Division, Fred Hutchinson Cancer Center, Seattle, Washington

The Explorers Virtual Internship at Fred Hutch is made possible by Pathways to Cancer Research (R25CA221770), a Youth Enjoy Science Award (YES/CURE), from the National Cancer Institute (NCI) at the National Institutes of Health.

How do different mutations in the ABCC1 transporter alter cGAMP export?

David Anthony, Dan Stetson, Immunology Department, University of Washington.

Research done as part of the BRIGHT-UP (Biomedical Research Internship for the Growth of High-school Trainees from Underrepresented Populations). 

The FHS Gut Biome Project: Microbiome and Mental Health

M. JIMENEZ GARCIA, P. GOSSMAN, A. LUU, A. D. LE, T. SUWANCHOTE , D. ANTHONY, A.N.LE, M. SOKRY, J. ANN BIRD, M. CAMPOS, TIM RENZ

M. Jinenez Garcia, P. Gossman, A. Luu, A.D. Le, T. Suwanchote, D. Anthony, A.N. Le, M. Sokry, J.A. Bird, M. Campos, Tim Renz, Advanced Biomedical Sciences, Foster High School

Rubber Hand Illusion Inducing Neurotechnology Operator

Kelly Chen, Jeffrey Herron, Ph.D, Center for Neurotechnology and Biorobotic Lab, University of Washington

Research done as part of the Center for Neurotechnology Young Scholar Program.

Keratin

Jennifer Tran, Tim Renz, AP Biology Foster High School

AP INVESTIGATION BLAST OPEN INQUIRY: KERATIN

Cindy Thai, Tim Renz, AP Biology Foster High School

AP Investigation 3: BLAST Open Inquiry

Nathan Nguyen, Tim Renz, AP Biology Foster High School

The Many Purposes of Keratin

Joey Gonzalez Montoya, Tim Renz, AP Biology Foster High School

The PAX1 Gene

Abe Rios, Tim Renz, AP Biology Foster High School

ATP Synthase

Brian Nguyen, Tim Renz, AP Biology Foster High School

BLAST Investigation-Keratin

Shafaq Buttar, Tim Renz, AP Biology Foster High School

Ubiquitin

Ryan Mathew, Tim Renz, AP Biology Foster High School

PAX1

Russel Ramos, Tim Renz, AP Biology Foster High School

The Effect of Water Temperature and Salinity on Surface Tension

Leary Nike Labanlic, Mehtaab Buttar, Roberto Ramirez, TJ Singh, Jesus De La Cruz, Tim Renz, Pre-AP Biology Foster High School

Forager Efficiency and Habitat Complexity

Fardeen Azizi, Frohar Azizi, Czarin Isabelle Dela Cruz, Faisal Sulayman, Tim Renz, Pre-AP Biology Foster High School

The Effect of Forager Learning on Survival

Courtney P., Catherine H., Alice R., Beck G., Tim Renz, Pre-AP Biology Foster High School