研究業績
2024
特許第7453662号 岡本賢治 登録2024年3月12日
特許第7453665号 岡本賢治 登録2024年3月12日
2023
Coordinated phosphate uptake by extracellular alkaline phosphatase and solute carrier transporters in marine diatoms. Hiroaki Matsui, Hisashi Harada, Kanako Maeda, Toshiki Sugiyama, Yohei Fukuchi, Nanae Kimura, Hermanus Nawaly, Yoshinori Tsuji, Yusuke Matsuda. New Phytologist 241(3) 1210-1221 (2023).
Pyrenoid-core CO2-evolving machinery is essential for diatom photosynthesis in elevated CO2. Ginga Shimakawa, Akane Okuyama, Hisashi Harada, Shuko Nakagaito, Yui Toyoshima, Kazuya Nagata, Yusuke Matsuda. Plant Physiology 193(4) 2298-2305 (2023).
微生物を活用した有用物質の製造技術 第7章 食品素材の生産 4. 大腸菌によるカロテノイド生産 原田尚志・竹村美保・三沢典彦 CMC出版 ISBN978-4-7813-1740-3 2023年5月31日
2022
Milk fermented with mushrooms prevents stroke in the stroke-prone spontaneously hypertensive rats independently of blood pressure. Zinat Mahal, Hiroyuki Matsuo, Hasan M Zahid, Yoshitomo Notsu, Hiroki Ohara, Kenji Okamoto, Toru Nabika. Journal of Stroke and Cerebrovascular Diseases 31(5) 106421 (2022).
食用きのこによる発酵豆乳に見いだしたDPP-4阻害ペプチドによる2型糖尿病の予防 岡本賢治 化学工業 73(10) 601~605 (2022).
2021
Production of the antihypertensive peptide Tyr-Pro from milk using the white-rot fungus Peniophora sp. in submerged fermentation and a jar fermentor. Kenji Okamoto, Ryosuke Ito, June Hayashi, Mizuki Tagawa. Dairy 2(3) 452-461 (2021).
Direct ethanol production from xylan and acorn using the starch-fermenting basidiomycete fungus Phlebia acerina. Kenji Okamoto, Takato Goda, Takeru Yamada, Masafumi Nagoshi. Fermentation 7(3) 116 (2021). https://www.mdpi.com/files/uploaded/covers/fermentation/big_cover-fermentation-v7-i3.png
Anti-hypertensive effect of the dipeptide, Tyrosyl-Proline, in RVLM; a microinjection study. Hasan Md. Zahid, Koichi Fujikawa, Hiroki Ohara, Kenji Okamoto, Toru Nabika. Journal of Hypertension 39 e252 (2021).
特許第6923882号 岡本賢治・並河 徹 登録2021年8月3日
Carboxylesterases for the hydrolysis of acetoacetate esters and their applications in terpenoid production using Escherichia coli. Hisashi Harada, Daiki Senda, Takanori Shima, Chika Nakane. Applied Microbiology and Biotechnology 105(14-15) 5821-5832 (2021).
Construction of transgenic Ipomoea obscura that exhibits new reddish leaf and flower colors due to introduction of β-carotene ketolase and hydroxylase genes. Motoyasu Otani, Kosuke Kitayama, Hiroki Ishikuro, Jun-Ichiro Hattan, Takashi Maoka, Hisashi Harada, Yuko Shiotani, Akane Eguchi, Eiji Nitasaka, Norihiko Misawa. Plant Biotechnology (Tokyo, Japan) 38(2) 219-226 (2021).
Pathway Engineering for High-Yield Production of Lutein in Escherichia coli. Miho Takemura, Akiko Kubo, Asuka Watanabe, Hanayo Sakuno, Yuka Minobe, Takehiko Sahara, Masahiro Murata, Michuhiro Araki, Hisashi Harada, Yoshinobu Terada, Katsuro Yaoi, Kohji Ohdan, Norihiko Misawa. Synthetic Biology 6(1) 1-9 (2021).
Pathway engineering using Escherichia coli to produce commercialized carotenoids. Hisashi Harada. Advances in Experimental Medicine and Biology 1261 191-199 (2021).
2020
Production of an antihypertensive peptide from milk by the brown rot fungus Neolentinus lepideus. Kenji Okamoto, Sayo Kawamura, Mizuki Tagawa, Toshifumi Mizuta, Hasan M. Zahi, Toru Nabika. European Food Research and Technology 246(9) 1773-1782 (2020).
食用きのこ発酵乳由来のDPP-4阻害ペプチド 岡本賢治 アグリバイオ 4(7) 54~55 (2020).
2019
Ethanol production from cheese whey and expired milk by the brown rot fungus Neolentinus lepideus. Kenji Okamoto, Saki Nakagawa, Ryuichi Kanawaku, Sayo Kawamura. Fermentation 5(2) 49 (2019).