We conduct both funded and non-funded studies aligned with our research focus on anxiety and related concerns, trauma, and substance use comorbidity in youth and adult populations. Our work spans diverse populations, including community participants, outpatient and inpatient populations, and individuals in residential settings. We have studied children, adolescents, college-age young adults, and adults using a range of methodologies, including psychophysiology, behavioral observations, dyadic (e.g., parent-child) interactions, stress induction, drug administration, and self-report measures. Through these efforts, we aim to generate knowledge that informs clinical practice while addressing mental health disparities in diverse communities.